Duvadilan Retards 40 Mg (Isoxsuprine Hcl)
Price range: $58.15 through $106.64Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 30 Capsule/s | $58.15 | $1.94 / capsule | ||
| 60 Capsule/s | $84.22 | $1.40 / capsule | ||
| 90 Capsule/s | $106.64 | $1.18 / capsule |
About Duvadilan Retards 40 Mg (Isoxsuprine Hcl)
Medicine information
- Active ingredient
- Isoxsuprine hydrochloride
- Delivery time
- 10-14 business days after dispatch for the United States, United Kingdom, Canada, and Australia; estimated only and customs or carrier delays may extend transit. Cheap_Generic_Med_Shipping_Coun…
- Indication
- Isoxsuprine is a smooth-muscle relaxant and peripheral vasodilator. Duvadilan Retard 40 mg has been used as a uterine relaxant in the management of threatened or active preterm labour and has also been used for symptoms associated with peripheral vascular disorders. The evidence and approved indications vary by country; U.S. labeling does not approve or recommend isoxsuprine for premature labour.
- Manufacturer
- Abbott India Limited
- Packaging
- Strip of 10 capsules
- Strength
- 40 mg
- Dosage form
- Sustained-release capsule
- Route
- Oral
Medicine overview
Duvadilan Retard 40 mg is an oral sustained-release capsule containing 40 mg of isoxsuprine hydrochloride. Abbott India lists the 40 mg capsule under its Duvadilan range, and an Indian institutional product listing specifically identifies Duvadilan Retard as a sustained-release isoxsuprine hydrochloride capsule. Isoxsuprine relaxes smooth muscle and also widens peripheral blood vessels. The retard formulation is designed to release the medicine over an extended period rather than all at once.
What it is used for
Duvadilan Retard has been used to relax uterine smooth muscle in women with threatened or active preterm labour and as maintenance treatment after contractions have been controlled. Isoxsuprine has also been used for peripheral vascular disorders associated with reduced blood flow, including Raynaud's disease and certain occlusive vascular diseases. Uses and regulatory approval differ between countries, so the indication on the local prescription and product information should be followed.
How it works
Isoxsuprine acts directly on smooth muscle and has beta-adrenergic activity. Its effects relax vascular smooth muscle, producing peripheral vasodilation, and can also reduce contractions of uterine smooth muscle. These actions explain its historical use both in disorders involving reduced peripheral circulation and as a tocolytic, meaning a medicine used to suppress premature uterine contractions. The clinical role and regulatory status of tocolytic use vary between countries.
How it is taken
Duvadilan Retard 40 mg is taken by mouth. Because it is a sustained-release capsule, it should be used according to the prescribed instructions for this formulation and should not be substituted dose-for-dose with immediate-release isoxsuprine products. Follow the prescribed schedule rather than changing the amount or frequency yourself. If isoxsuprine causes stomach upset, oral isoxsuprine may be taken with food or milk.
Important warnings
Isoxsuprine can lower blood pressure and increase heart rate, so particular caution is appropriate in people with cardiovascular disease or a tendency to hypotension. Tell the prescriber about angina, recent heart attack or stroke, bleeding problems, glaucoma, or significant arterial disease. It should not be used immediately after childbirth or when arterial bleeding is present. Seek prompt medical attention for chest pain, fainting, marked shortness of breath, a very fast heartbeat, or a severe skin rash. When isoxsuprine has been used for preterm labour, maternal and fetal tachycardia have been reported; pulmonary edema has also been reported with beta-adrenergic stimulants.
Side effects and monitoring
Common or less serious effects can include nausea, vomiting, dizziness, weakness, abdominal discomfort, and symptoms related to lowered blood pressure. More important reactions reported with oral isoxsuprine include hypotension, tachycardia, chest pain, severe rash, faintness, and shortness of breath. Medical attention is needed for chest pain, fainting, breathing difficulty, a markedly fast heartbeat, or a significant rash. When used during pregnancy for uterine relaxation, maternal heart rate, blood pressure, uterine activity, and fetal condition may require clinical monitoring.
Pregnancy
Isoxsuprine has been used during pregnancy as a tocolytic to suppress premature uterine contractions, including sustained-release 40 mg maintenance therapy in published clinical research. However, its role and approval differ internationally; U.S. labeling states that isoxsuprine is neither approved nor recommended for treating premature labour. Use during pregnancy should therefore be only under obstetric supervision after assessment of the maternal and fetal situation.
Food and drink
If oral isoxsuprine causes stomach upset, it may be taken with meals or milk.
Storage
Store in a closed container at room temperature, protected from heat, moisture, and direct light, and keep from freezing. Keep the medicine out of reach of children.
Frequently asked questions
Why would Duvadilan Retard be prescribed during pregnancy?
Isoxsuprine has been used to relax uterine smooth muscle and suppress premature contractions. Its role and approval vary between countries, so use during pregnancy should be directed and monitored by an obstetric clinician.
Can Duvadilan Retard stop premature contractions completely?
It can reduce uterine contractions in some patients, but response varies and contractions during pregnancy require medical assessment. Published studies have evaluated isoxsuprine for threatened or active preterm labour, but regulatory recommendations are not uniform internationally.
Can Duvadilan Retard make my heart beat faster?
Yes. Tachycardia, or an abnormally fast heartbeat, is a recognized adverse effect of isoxsuprine. Contact a healthcare professional promptly if a rapid heartbeat is marked, persistent, or accompanied by chest pain, fainting, or breathing difficulty.
Can Duvadilan Retard cause dizziness or low blood pressure?
Yes. Isoxsuprine can cause dizziness and hypotension. Take care when standing up, and seek medical advice if dizziness is persistent or severe or if you faint.
Should Duvadilan Retard 40 mg capsules be treated the same as Duvadilan 10 mg tablets?
No. The 40 mg product is a sustained-release capsule, while Abbott also lists a separate 10 mg tablet. Different strengths and release formulations should not be substituted or used interchangeably without the prescriber's instructions.
Can I take Duvadilan Retard with food?
Oral isoxsuprine may be taken with food or milk if it causes stomach upset. No additional product-specific food restriction for Duvadilan Retard 40 mg was verified.
What should I do if I develop chest pain or shortness of breath while taking isoxsuprine?
Seek prompt medical attention. Chest pain and shortness of breath are among the potentially important adverse effects reported with isoxsuprine.
Does Cheap Generic Med ship Duvadilan Retard internationally?
Cheap Generic Med serves multiple international destinations, including the United States, United Kingdom, Canada, Australia, Singapore, New Zealand, Japan, and South Africa. Shipping availability does not establish that personal import is lawful; prescription and import requirements can vary by destination and individual circumstances.
Will my Duvadilan Retard order have tracking?
Under Cheap Generic Med's standard international fulfilment model, tracked shipping is used and a tracking number should be provided after dispatch. Carrier systems may take 24-72 hours to begin displaying movement.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Active Ingredients | Isoxsuprine Hcl |
|---|---|
| Manufacturer | Abbott Pharmaceuticals, India |
| Packaging | Qty |
| strength | 40mg |
| Delivery Time | 6 To 15 days |
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