Danogen 50 Mg (Danazol)
Price range: $56.52 through $102.21Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 30 Capsule/s | $56.52 | $1.88 / capsule | ||
| 60 Capsule/s | $81.08 | $1.35 / capsule | ||
| 90 Capsule/s | $102.21 | $1.14 / capsule |
About Danogen 50 Mg (Danazol)
Medicine information
- Active ingredient
- Danazol
- Delivery time
- Typically 10–21 business days after dispatch, depending on destination. Customs or local postal delays may extend delivery time.
- Indication
- Treatment of endometriosis amenable to hormonal management and prevention of attacks of hereditary angioedema.
- Manufacturer
- Cipla Limited
- Packaging
- 10 capsules
- Strength
- 50 mg
- Dosage form
- Capsule
- Route
- Oral
Medicine overview
Danogen 50 mg is an oral capsule containing 50 mg of danazol, a synthetic steroid with androgenic and hormone-suppressing effects. The Danogen 50 mg product is manufactured by Cipla Limited. Danazol is used for hormone-responsive endometriosis and can also be used to prevent attacks of hereditary angioedema. Its hormonal effects can cause significant adverse reactions, so treatment requires medical supervision and appropriate monitoring.
What it is used for
Danazol is used to treat endometriosis that is suitable for hormonal treatment. By suppressing hormonal stimulation of endometrial tissue, it can reduce endometriosis-related symptoms. Danazol is also indicated for prevention of hereditary angioedema attacks, including swelling affecting the skin, abdomen, or airway. The appropriate indication and treatment regimen must be determined by the prescriber.
How it works
Danazol suppresses the pituitary-ovarian hormonal system and has weak androgenic activity. In endometriosis, its hormonal effects reduce stimulation of endometrial tissue, producing changes that can make endometriotic lesions inactive. In hereditary angioedema, danazol increases levels of deficient or reduced complement-related proteins, including C1 esterase inhibitor, which helps reduce susceptibility to swelling attacks.
How it is taken
Danogen is taken by mouth as a capsule. Use it exactly according to the prescribed regimen; the required amount and duration differ substantially according to the condition being treated and individual response. For endometriosis, treatment should not be started until pregnancy has been excluded. Food can substantially increase danazol absorption, particularly a meal containing more than 30 g of fat, so follow the prescriber's instructions about how to take each dose in relation to meals.
Important warnings
Danazol must not be used during pregnancy or breastfeeding. It is also contraindicated in people with unexplained abnormal genital bleeding, markedly impaired liver, kidney, or heart function, porphyria, androgen-dependent tumors, active or previous thrombosis or thromboembolic disease, or hypersensitivity to danazol. Serious reported risks include blood clots and stroke, severe liver injury, peliosis hepatis, hepatic adenoma, and benign intracranial hypertension. Some androgenic changes, particularly voice changes, may not fully reverse. Important interactions include warfarin, carbamazepine, cyclosporine, tacrolimus, antidiabetic medicines, and certain statins including simvastatin, atorvastatin, and lovastatin. Urgent assessment is needed for sudden chest pain or breathlessness, symptoms suggesting a blood clot or stroke, jaundice, or severe headache with vomiting or visual disturbance.
Side effects and monitoring
Common or characteristic effects include weight gain, acne, oily skin, mild increased body or facial hair, fluid retention, hair loss, flushing, sweating, vaginal dryness, menstrual changes, spotting, or absence of periods. Voice deepening or other voice changes can occur and may persist after treatment. Serious or less common effects include liver injury, jaundice, thrombosis, stroke, intracranial hypertension, severe skin reactions, and significant blood-count abnormalities. Periodic liver-function testing is recommended, and hematologic monitoring should be considered. Danazol can also alter cholesterol and other laboratory measurements. Seek prompt medical attention for jaundice, severe or persistent headache with visual changes, signs of thrombosis, severe allergic or skin reactions, or other significant new symptoms.
Pregnancy
Danazol is contraindicated during pregnancy because fetal exposure can produce androgenic effects, particularly masculinization of a female fetus. Pregnancy should be excluded before treatment begins, and a non-hormonal contraceptive method is recommended during therapy. If pregnancy occurs during treatment, medical advice should be obtained promptly.
Breastfeeding
Danazol is contraindicated during breastfeeding. Current evidence does not provide adequate information about danazol exposure through human milk, and an alternative medicine is preferred during lactation.
Food, drink and interactions
Avoid alcohol while taking danazol. Patient guidance reports that combining alcohol with danazol can cause nausea or shortness of breath.
Food and drink
Food can substantially affect danazol absorption. Studies found considerably higher danazol exposure after a meal containing more than 30 g of fat compared with fasting conditions. Follow the prescribed instructions consistently regarding meals rather than changing between fed and fasting administration without medical guidance.
Storage
Store at 20°C to 25°C (68°F to 77°F) and keep the medicine in a well-closed container. Keep out of reach of children.
Frequently asked questions
Will danazol stop my periods while I am taking it?
It can. Danazol can cause spotting, changes in menstrual timing, or complete absence of periods. Menstrual cycles and ovulation usually return after treatment, although persistent absence of periods has occasionally been reported.
Can Danogen cause weight gain or acne?
Yes. Weight gain, acne, and oily skin are recognized androgen-like effects of danazol. Increased body or facial hair, fluid retention, and hair loss can also occur.
Can danazol make my voice deeper?
Yes. Hoarseness, instability, or deepening of the voice can occur, and some voice changes may persist after treatment ends. Report a noticeable voice change to the prescriber.
Does danazol cause hair loss?
It can. Hair loss has been reported during danazol treatment, along with other androgenic effects such as acne and increased body or facial hair.
Can I become pregnant while taking Danogen?
Pregnancy must be avoided during danazol treatment because fetal exposure can cause serious androgenic effects. Pregnancy should be excluded before starting treatment, and non-hormonal contraception is recommended during therapy.
Does food affect Danogen?
Yes. Food, particularly a meal containing more than 30 g of fat, can substantially increase danazol absorption. Follow the prescriber's instructions consistently about taking it in relation to meals.
What monitoring may be needed while taking danazol?
Periodic liver-function tests are recommended because danazol can cause liver abnormalities, and blood-count monitoring may also be considered. The medicine can also affect lipid levels and several laboratory test results.
Can Cheap Generic Med ship Danogen internationally?
Cheap Generic Med serves multiple international destinations, including the United States, United Kingdom, Canada, Australia, Singapore, New Zealand, Japan, and South Africa. Shipping availability does not guarantee that personal import is permitted, and prescription or customs requirements may apply in the destination country.
Will a Cheap Generic Med order have tracking?
Under the standard international fulfilment model, tracked shipping is used and a tracking number should be provided after dispatch. Carrier systems can take 24–72 hours to begin displaying movement.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Active Ingredients | Danazol |
|---|---|
| Manufacturer | Cipla, India |
| Packaging | Qty |
| strength | 50mg |
| Delivery Time | 6 To 15 days |
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