Ruftuf 60 Mg Tablet (Raloxifene)
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About Ruftuf 60 Mg Tablet (Raloxifene)
Medicine information
- Active ingredient
- Raloxifene
- Indication
- Treatment and prevention of osteoporosis in postmenopausal women. Raloxifene is also indicated for reducing the risk of invasive breast cancer in certain postmenopausal women with osteoporosis or at high risk of invasive breast cancer; however, Ruftuf-specific sources identify postmenopausal osteoporosis as the product's use.
- Manufacturer
- Ajanta Pharma Limited
- Packaging
- Strip of 10 tablets
- Strength
- 60 mg
- Dosage form
- Tablet
- Route
- Oral
Medicine overview
Ruftuf 60 Mg Tablet contains raloxifene, a selective estrogen receptor modulator (SERM). It is used to treat and prevent osteoporosis in postmenopausal women. Raloxifene acts like estrogen in some tissues, particularly bone, helping reduce the bone loss that can occur after menopause. The medicine is taken by mouth. Raloxifene also has established indications for reducing invasive breast cancer risk in certain postmenopausal women, although it does not treat existing breast cancer.
What it is used for
Ruftuf 60 Mg Tablet is used for the treatment and prevention of osteoporosis after menopause. Raloxifene helps maintain bone mineral density and lowers the risk of vertebral fractures associated with postmenopausal osteoporosis. Raloxifene also has approved uses for reducing invasive breast cancer risk in selected postmenopausal women, but it is not a treatment for invasive breast cancer and does not prevent recurrence of an existing breast cancer.
How it works
Raloxifene is a selective estrogen receptor modulator, meaning its effects on estrogen receptors differ between tissues. In bone, it acts in an estrogen-like way and reduces the increased bone breakdown associated with menopause, helping preserve bone density. In breast tissue, raloxifene blocks some estrogen effects. This explains both its role in postmenopausal osteoporosis and its established ability to reduce the risk of invasive breast cancer in certain postmenopausal women.
How it is taken
Raloxifene tablets are taken by mouth. The verified standard administration for raloxifene 60 mg is one tablet once daily, at any time of day, with or without food. Take the medicine according to the prescription and do not change or stop treatment without medical advice. For osteoporosis treatment or prevention, adequate calcium and vitamin D intake should be maintained; supplementation may be advised when dietary intake is insufficient.
Important warnings
Do not use raloxifene if there is an active or previous history of venous thromboembolism, including deep vein thrombosis, pulmonary embolism, or retinal vein thrombosis. Raloxifene increases the risk of venous blood clots and should be stopped at least 72 hours before and during prolonged immobilization, such as after surgery or during prolonged bed rest, under medical direction. Seek urgent medical attention for unexplained leg swelling or pain, sudden chest pain, shortness of breath, coughing up blood, or sudden vision changes. An increased risk of death from stroke was observed in postmenopausal women with coronary heart disease or increased coronary risk; individual stroke risk should therefore be assessed. Raloxifene is not intended to prevent cardiovascular disease and is not recommended for premenopausal women. Use requires caution with hepatic impairment and moderate or severe renal impairment. Cholestyramine and similar anion-exchange resins should not be co-administered; warfarin users may require closer prothrombin-time monitoring when raloxifene is started or stopped. Concomitant systemic estrogen therapy is not recommended.
Side effects and monitoring
Common effects include hot flashes, leg cramps, peripheral swelling, flu-like symptoms, joint pain, and increased sweating. Other reported effects include headache, nausea, diarrhea, and dizziness. Serious concerns include deep vein thrombosis, pulmonary embolism, retinal vein thrombosis, and stroke; urgent assessment is needed for symptoms suggesting a blood clot or sudden neurological or visual changes. Women with previous marked hypertriglyceridemia during estrogen treatment may require serum triglyceride monitoring. Patients taking warfarin or related anticoagulants may require closer prothrombin-time/INR monitoring when raloxifene is started or stopped.
Pregnancy
Raloxifene is contraindicated during pregnancy and is not indicated for women of reproductive potential. Its mechanism of action may interfere with estrogen functions important during pregnancy and it may cause fetal harm.
Breastfeeding
Raloxifene is not indicated for women of reproductive potential. It is not known whether raloxifene is present in human milk, affects a breastfed child, or affects milk production. Its estrogen-modulating action may interfere with normal estrogen functions in breast tissue during lactation.
Food, drink and interactions
No specific direct alcohol interaction is established in the prescribing information reviewed. For osteoporosis management, excessive alcohol consumption is discouraged because it is a modifiable risk factor affecting bone health.
Food and drink
Raloxifene may be taken with or without food. For osteoporosis treatment or prevention, adequate dietary calcium and vitamin D are important, and supplementation may be recommended when intake is inadequate.
Storage
Store at controlled room temperature, 20°C to 25°C (68°F to 77°F), with permitted excursions from 15°C to 30°C under USP controlled-room-temperature conditions. Keep the medicine in a tightly closed container and away from excess heat and moisture.
Frequently asked questions
Can raloxifene make hot flashes worse?
Yes. Raloxifene can cause or increase hot flashes, particularly after treatment begins. It is not a treatment for menopausal hot flashes.
Why do I need to be careful about blood clots while taking raloxifene?
Raloxifene increases the risk of venous blood clots, including deep vein thrombosis and pulmonary embolism. Seek urgent medical attention for new leg swelling or pain, sudden chest pain, shortness of breath, or coughing up blood.
Do I need to stop raloxifene before surgery?
Raloxifene should be discontinued at least 72 hours before and during prolonged immobilization because being immobile further increases the risk of venous blood clots. Follow the prescriber's instructions about when to stop and restart it.
Can I take raloxifene with food?
Yes. Raloxifene can be taken with or without food and at any time of day.
Should I take calcium and vitamin D with raloxifene?
Adequate calcium and vitamin D intake is recommended when raloxifene is being used for osteoporosis. Supplements may be advised when dietary intake is insufficient.
Can raloxifene be taken with warfarin?
It may be used together under medical supervision, but prothrombin time should be monitored more closely when raloxifene is started or stopped in someone taking warfarin or related coumarin anticoagulants.
Does raloxifene treat breast cancer?
No. Raloxifene can reduce the risk of invasive breast cancer in certain postmenopausal women, but it is not indicated to treat invasive breast cancer or prevent recurrence in women who have already had it.
Can Cheap Generic Med ship Ruftuf to the United States?
Cheap Generic Med serves the United States under its international shipping model. Delivery is typically estimated at 10–14 business days after dispatch, although customs or carrier delays may extend transit. Prescription and import requirements may apply.
Will my Cheap Generic Med order have tracking?
Tracked international shipping is used under the standard fulfilment model. A tracking number should be provided after dispatch, although carrier systems may take 24–72 hours to begin showing movement.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
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