Ledronzol 4 Mg Injection (Zoledronic Acid)
Price range: $114.38 through $273.00Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 3 Injection | $114.38 | $38.13 / injection | ||
| 6 Injection | $194.70 | $32.45 / injection | ||
| 9 Injection | $273.00 | $30.33 / injection |
About Ledronzol 4 Mg Injection (Zoledronic Acid)
Medicine information
- Active ingredient
- Zoledronic acid
- Delivery time
- 14-21 business days after dispatch; estimated only, and customs or local carrier delays may extend transit. Cheap_Generic_Med_Shipping_Coun…
- Indication
- Treatment of hypercalcemia of malignancy and treatment of patients with multiple myeloma or documented bone metastases from solid tumors, together with standard antineoplastic therapy. For prostate cancer, the disease should have progressed after at least one hormonal therapy. These indications correspond to the verified 4 mg zoledronic acid intravenous formulation.
- Manufacturer
- Alkem Laboratories Ltd
- Packaging
- 1 × 5 mL vial
- Strength
- 4 mg
- Dosage form
- Injection; concentrate for solution for intravenous infusion
- Route
- Intravenous infusion
Medicine overview
Ledronzol 4 Mg Injection contains zoledronic acid, a bisphosphonate medicine that reduces abnormal breakdown of bone. The verified product is marketed by Alkem Laboratories Ltd and is supplied as a 4 mg injection in a 5 mL vial. Zoledronic acid 4 mg intravenous formulations are used mainly for cancer-related high blood calcium and bone complications associated with multiple myeloma or solid tumors that have spread to bone. The medicine is administered by intravenous infusion under healthcare supervision.
What it is used for
Zoledronic acid 4 mg intravenous treatment is used for hypercalcemia of malignancy, meaning abnormally high blood calcium caused by cancer. It is also used with standard cancer treatment in patients with multiple myeloma or documented bone metastases from solid tumors to reduce skeletal complications. The 4 mg oncology formulation should not be confused with zoledronic acid 5 mg formulations used for indications such as osteoporosis and Paget's disease.
How it works
Zoledronic acid is a bisphosphonate that binds strongly to mineralized bone. It inhibits osteoclasts, the cells responsible for breaking down old bone tissue. Reducing osteoclast activity slows excessive bone resorption and decreases the release of calcium from bone into the bloodstream. This action helps lower cancer-related high calcium levels and helps reduce skeletal complications when cancer or multiple myeloma affects bone.
How it is taken
Ledronzol is administered intravenously by a healthcare professional and should not be self-administered. For the verified 4 mg/5 mL zoledronic acid concentrate formulation, the required amount is diluted in 100 mL of 0.9% sodium chloride or 5% dextrose and infused over at least 15 minutes. It must not be mixed with calcium-containing or other divalent-cation-containing infusion solutions. Kidney function should be assessed before treatment, and the prescribed dose may require adjustment according to renal function.
Important warnings
Do not use zoledronic acid in patients with hypersensitivity to zoledronic acid or formulation components. Kidney injury, including renal failure, can occur; renal function and serum creatinine should be assessed before treatment, and dehydration should be corrected. Hypocalcemia must be corrected before treatment, with calcium and other relevant electrolytes monitored as appropriate. Osteonecrosis of the jaw has been reported, so a dental examination and necessary preventive dental care should be completed before treatment where possible; invasive dental procedures during therapy require careful medical and dental assessment. Other important risks include severe bone, joint or muscle pain and atypical femoral fractures; new thigh or groin pain should be evaluated. Aminoglycosides, calcitonin and loop diuretics can increase the risk of hypocalcemia, while potentially nephrotoxic medicines may increase renal risk. Patients receiving this formulation should not simultaneously receive another zoledronic-acid product or another bisphosphonate unless specifically directed by the treating clinician.
Side effects and monitoring
Common effects reported with 4 mg zoledronic acid include nausea, fatigue, anemia, bone pain, constipation, fever, vomiting and shortness of breath. Flu-like symptoms, muscle or joint aches and other acute-phase reactions may occur after an infusion. Serious risks include kidney impairment or renal failure, severe hypocalcemia, osteonecrosis of the jaw, severe musculoskeletal pain, atypical femoral fracture and serious hypersensitivity reactions. Seek prompt medical attention for facial or throat swelling, breathing difficulty, severe muscle spasms or tingling suggestive of low calcium, markedly reduced urination, persistent jaw pain or non-healing mouth sores, or unexplained thigh or groin pain. Serum creatinine should be checked before doses, with calcium and other electrolytes monitored when clinically appropriate.
Pregnancy
Zoledronic acid can cause fetal harm and should not be administered during pregnancy. Pregnancy status should be verified before treatment in females of reproductive potential, and effective contraception is advised during and after treatment because zoledronic acid can remain incorporated in bone for a prolonged period.
Breastfeeding
Breastfeeding is not advised during and after zoledronic acid treatment. It is unknown whether zoledronic acid is present in human milk, but the medicine remains bound to bone and may be released for an extended period, creating a potential risk of serious adverse effects in a breastfed child.
Food and drink
No specific food restriction is generally required; patients can continue their normal diet unless instructed otherwise. Adequate hydration is important, particularly around treatment, because dehydration can increase the risk of kidney complications. Calcium and vitamin D supplementation may be prescribed for patients receiving treatment for multiple myeloma or bone metastases.
Storage
Store at 20°C to 25°C. After dilution, if the solution is not used immediately, the verified 4 mg/5 mL formulation may be refrigerated at 2°C to 8°C; the total period between dilution, refrigerated storage and completion of administration must not exceed 24 hours. Any unused portion of a single-dose vial should be discarded.
Frequently asked questions
What should I expect after my first zoledronic acid infusion?
Some people develop fever, fatigue, bone or muscle aches, nausea, or other flu-like symptoms after an infusion. Contact your healthcare team if symptoms are severe, persistent, or accompanied by signs of an allergic reaction or low calcium.
Why do I need a dental check before Ledronzol treatment?
Zoledronic acid is associated with a rare but serious condition called osteonecrosis of the jaw. A preventive dental examination is recommended before treatment, and your doctor and dentist should know about zoledronic acid therapy before invasive dental procedures.
Why is kidney function checked before each infusion?
Zoledronic acid can impair kidney function and, rarely, cause renal failure. Serum creatinine is therefore checked before treatment, and kidney function can affect whether treatment is appropriate and what dose is used.
Do I need to be hydrated before receiving Ledronzol?
Yes, adequate hydration is important, particularly when zoledronic acid is being used for hypercalcemia of malignancy. Dehydration should be corrected before treatment because it can increase kidney-related risks.
Why might calcium and vitamin D be prescribed with zoledronic acid?
Zoledronic acid can lower blood calcium. Calcium and vitamin D supplementation is recommended in appropriate patients, particularly those receiving the 4 mg formulation for multiple myeloma or bone metastases.
Can I have a tooth extraction while receiving zoledronic acid?
Invasive dental procedures require careful assessment because they can be associated with osteonecrosis of the jaw in patients receiving bisphosphonates. Tell both your treating clinician and dentist about the medicine before arranging an extraction, implant, or other invasive dental procedure.
Can Cheap Generic Med ship Ledronzol to the United States?
Cheap Generic Med serves the United States under its international shipping model. Delivery is typically estimated at 10-14 business days after dispatch, but customs or carrier delays may extend transit, and prescription and personal-import requirements may apply.
Will my Cheap Generic Med Ledronzol order have tracking?
Tracked international shipping is used under the standard fulfilment model. A tracking number should be provided after dispatch, although it may take 24-72 hours for movement to appear in the carrier system.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Active Ingredients | Zoledronic acid (4Mg) |
|---|---|
| Manufacturer | Alkem Laboratories Ltd |
| Packaging | Qty |
| strength | 4mg |
| Delivery Time | 6 To 15 days |
Related products
Danogen 100 Mg (Danazol)
Danogen 200 Mg (Danazol)
Reviews
There are no reviews yet.