Evadiol 2 Mg (Estradiol)
Price range: $68.74 through $117.89Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 56 Tablet/s | $68.74 | $1.23 / tablet | ||
| 112 Tablet/s | $104.62 | $0.93 / tablet | ||
| 140 Tablet/s | $117.89 | $0.84 / tablet |
About Evadiol 2 Mg (Estradiol)
Medicine information
- Active ingredient
- Estradiol valerate
- Delivery time
- United States, United Kingdom, Canada, Australia: typically 10–14 business days after dispatch; Europe: 12–18 business days; Middle East and other served destinations: 14–21 business days. These are estimates and customs or local carrier delays may extend delivery. Cheap_Generic_Med_Shipping_Coun…
- Indication
- Hormone replacement therapy (HRT) for estrogen-deficiency symptoms associated with peri- and postmenopause; estrogen therapy may also be used for prevention of postmenopausal osteoporosis in appropriately selected patients at increased fracture risk when other approved osteoporosis medicines are unsuitable.
- Manufacturer
- Intas Pharmaceuticals Ltd.
- Packaging
- 28 tablets
- Strength
- 2 mg
- Dosage form
- Tablet
- Route
- Oral
Medicine overview
Evadiol 2 mg is an oral estrogen medicine manufactured by Intas Pharmaceuticals Ltd. Each tablet contains 2 mg of estradiol valerate, an estrogen ester that is converted in the body to estradiol. It is used as hormone replacement therapy (HRT), particularly for symptoms caused by reduced estrogen levels around and after menopause. Estrogen therapy can help relieve symptoms such as hot flushes and other estrogen-deficiency symptoms and may have a role in preventing postmenopausal bone loss in appropriately selected patients.
What it is used for
Evadiol is used for estrogen replacement when the body is producing insufficient estrogen, including treatment of estrogen-deficiency symptoms associated with peri- and postmenopause. These can include hot flushes, sweating and other menopausal symptoms. Estradiol valerate therapy may also be used to help prevent osteoporosis after menopause in patients at increased fracture risk when other medicines approved for osteoporosis prevention are unsuitable or contraindicated.
How it works
Estradiol valerate is an ester of estradiol, a naturally occurring human estrogen. After oral administration, estradiol valerate is absorbed and rapidly converted to estradiol. The resulting estrogen replaces some of the hormone that declines during menopause or other estrogen-deficient states. By activating estrogen receptors in estrogen-responsive tissues, it can reduce menopausal symptoms and help limit the accelerated loss of bone associated with estrogen deficiency.
How it is taken
Evadiol is taken by mouth according to the prescribed regimen. Estradiol valerate tablets can be taken with or without food and should be swallowed with liquid. Take the medicine consistently as directed by the prescriber. Do not alter the prescribed dose or treatment schedule without medical advice. For patients who still have a uterus, a clinician may prescribe a progestogen alongside systemic estrogen to reduce the risk of endometrial hyperplasia and cancer.
Important warnings
Do not use systemic estradiol valerate in patients with known, previous or suspected breast cancer; known or suspected estrogen-dependent cancer; unexplained genital bleeding; untreated endometrial hyperplasia; current or previous unexplained venous thromboembolism such as deep-vein thrombosis or pulmonary embolism; known thrombophilic disorders; active or recent arterial thromboembolic disease such as myocardial infarction or angina; acute or significant unresolved liver disease; porphyria; or hypersensitivity to the medicine. Systemic estrogen can increase the risk of endometrial hyperplasia and cancer when used without adequate progestogen in a patient with an intact uterus. HRT is also associated with clinically important risks including venous thromboembolism, stroke, breast cancer and gallbladder disease, with individual risk depending on factors such as treatment type, duration and medical history. Tell the prescriber about migraine, hypertension, diabetes, endometriosis, fibroids, epilepsy, asthma, gallstones, lupus and risk factors for blood clots or estrogen-dependent cancers. Important interactions include enzyme-inducing medicines such as carbamazepine, phenytoin, rifampicin and St John's wort; some antifungals and macrolide antibiotics can increase estrogen exposure. Estrogen may also reduce lamotrigine concentrations. Seek urgent medical assessment for symptoms suggesting a blood clot or stroke, significant unexplained vaginal bleeding, jaundice, a major rise in blood pressure or a new migraine-type headache.
Side effects and monitoring
Commonly reported effects with oral estrogen/HRT can include headache, nausea, abdominal discomfort or bloating, breast tenderness or breast symptoms, changes in vaginal or uterine bleeding, mood changes, dizziness and changes in weight. Less common or serious problems include venous thromboembolism, stroke, myocardial infarction, gallbladder disease, liver problems, severe hypersensitivity reactions and estrogen-dependent cancers. Seek prompt medical attention for unexplained postmenopausal bleeding, symptoms of a blood clot, sudden neurological symptoms, jaundice or a severe allergic reaction. Patients using HRT should have periodic clinical review, with breast and other appropriate screening performed according to current clinical recommendations.
Pregnancy
Estradiol valerate HRT is not indicated during pregnancy. If pregnancy occurs during treatment, the medicine should be discontinued and the prescriber contacted.
Breastfeeding
Estradiol valerate HRT is not indicated during breastfeeding.
Food and drink
The tablets may be taken with or without food. Grapefruit juice can inhibit CYP3A4 and may increase estrogen concentrations, so patients should discuss regular grapefruit consumption with their healthcare professional.
Frequently asked questions
Will estradiol tablets help with hot flushes and other menopause symptoms?
Yes. Systemic estrogen replacement can reduce hot flushes and other symptoms caused by declining estrogen levels around and after menopause.
Can I take Evadiol with food?
Yes. Oral estradiol valerate tablets can be taken with or without food. Follow the same prescribed treatment schedule consistently.
What happens if I still have my uterus and take estrogen?
Estrogen used on its own can increase the risk of excessive growth of the uterine lining and endometrial cancer. A clinician will usually consider adding a progestogen for patients with an intact uterus.
Is unexpected vaginal bleeding while taking estrogen something I should report?
Yes. Unexpected, persistent or postmenopausal vaginal bleeding should be reported to a healthcare professional so the cause can be assessed.
Can estradiol increase the risk of blood clots?
Yes. Systemic HRT is associated with an increased risk of venous blood clots in some patients. Seek urgent medical attention for symptoms such as painful swelling of a leg, sudden chest pain or unexplained shortness of breath.
Can I use Evadiol during pregnancy or breastfeeding?
No. Estradiol valerate HRT is not indicated during pregnancy or breastfeeding. Contact the prescriber if pregnancy occurs during treatment.
Is Evadiol a contraceptive?
No. Estradiol valerate HRT should not be relied upon to prevent pregnancy. A healthcare professional can advise about appropriate contraception when needed.
Can Cheap Generic Med ship Evadiol internationally?
Cheap Generic Med serves multiple international destinations, including the United States, United Kingdom, Canada, Australia, Singapore, New Zealand, Japan and South Africa. Shipping availability does not establish that personal import is lawful; prescription, customs and import requirements can vary by destination and circumstances.
Will my Cheap Generic Med order have tracking?
Under the standard fulfilment model, tracked international shipping is used and a tracking number should be provided after dispatch. New tracking numbers may take 24–72 hours to begin showing movement in the carrier system.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Indication | Provides relief from vaginal dryness, improving comfort during intercourse. |
|---|---|
| Packaging | Qty |
| Delivery Time | 6 To 15 days |
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