Zyfoss 4 Mg Injection

Dr. Emily Brown

Dr. Ryan Mitchell

SKU

CMS3418

USA Brand Name

Zometa

Strength

4mg

Generic Name

Zoledronic Acid

Manufacturer

Fresenius Kabi

## Zyfoss 4 Mg Injection (Zoledronic Acid)

## What Is The Generic Name For Zyfoss 4 Mg Injection:

Zoledronic Acid is the generic version for Zyfoss 4 mg Injection

## Which USA Brand is Equivalent To Zyfoss 4 Mg Injection (Zoledronic Acid):

Zometa

## About Zyfoss 4 Mg Injection (Zoledronic Acid)

Zyfoss 4 mg Injection contains an active ingredient, Zoledronic Acid, which is used to treat or prevent osteoporosis in postmenopausal women. This medicine is also used for the prevention & treatment of osteoporosis in men & women who are on corticosteroid therapy. Zyfoss 4 mg Injection can also be used to bring down high levels of calcium in the blood which may be caused by some cancers. This is also used to treat Paget’s disease. In cancer therapy, Zoledronic Acid can be used to prevent or treat bone damage caused by cancer cells. Osteoporosis is a disease state in which bones get thin & weak due to low bone mass (bone density). This makes bones fragile & increased risk of fractures from slightest trauma. This medicine is available at all the leading pharmacy, drugstores, & medical supply stores & must be taken strictly by doctor’s prescription only.

## Manufacturer :

Dabur India Ltd. is one of the leading pharmaceutical companies which manufacture Zyfoss 4 mg Injection.

## Strength :

Zyfoss 4 mg Injection contains an active constituent, Zoledronic Acid. It is obtainable in other substitutes also at all the leading online pharmacy, drugstores, and medical supply stores.

## What Are The Uses Of The Zyfoss 4 Mg Injection (Zoledronic Acid):

Zyfoss 4 mg Injection is used in the treatment in following conditions:

Osteolytic bone lesions of multiple myeloma

Osteolytic bone metastases of solid tumours

Hypercalcemia of malignancy

Paget’s disease

Osteoporosis

## How Zyfoss 4 Mg Injection (Zoledronic Acid) Works:

Zyfoss 4 mg Injection has an active ingredient; Zoledronic Acid is a bisphosphonate which works by suppressing the activity of osteoclasts, cells which cause destruction of bone. This strengthens the bones & minimizes the risk of fractures. Zoledronic acid is an efficient inhibitor of bone resorption. It inhibits osteoclast proliferation & induces osteoclast apoptotic cell death. Its effectiveness results from its high affinity for mineralized bone & especially for sites of high bone turnover.

## Before You Use Zyfoss 4 Mg Injection (Zoledronic Acid):

Make sure that:

You are not allergic to Zoledronic Acid

You are not having any serious Disease

Your doctor must be learned about your medicinal history like your pre- existing disease, surgeries & Medications, Supplements, Food Habits, lifestyle, etc.

## What Should You Avoid While Taking Zyfoss 4 Mg Injection (Zoledronic Acid):

You should avoid taking alcohol

You should avoid driving

You should avoid taking Medicines without prescriptions

## When Not To Use Zyfoss 4 Mg Injection (Zoledronic Acid):

You should not take Zyfoss 4 mg Injection if you:

Have ever noticed any Allergy/Hypersensitivity

Have liver problems

Have kidney problems

Are pregnant

Have severe bone, joint and/or muscle pain

Have Flu-like symptoms

Have Thigh bone fracture

Have infections

Are breastfeeding

## Tell Your Doctor If You:

Have Allergy to the Injection

Are taking Alcohol or Other Drugs

Have Liver disease

Have kidney disorder

Have infections

## Dosage :

Zyfoss 4 mg Injection contains an active ingredient, Zoledronic Acid, which is used to treat or prevent osteoporosis. This medicine is available in different substitutes & strengths & has got to be purchased or given on doctor’s prescription only. You must consult your physician for adjustment of dosage & time of the medicine because age and severity of the disease differ from person to person and it can only be best judged by your doctor.

Adults are advised to take Zyfoss 4 mg Injection at a fixed time with or without food as instructed by your Doctor. You must take Zyfoss 4 mg Injection regularly on time for better results.

## How Much Of The Zyfoss 4 Mg Injection (Zoledronic Acid) to Be Used:

As Zyfoss 4 mg Injection is available in various strengths and substitutes, Patients are always advised to follow their doctor’s prescriptions and instructions to take Zyfoss 4 mg Injection. You must not take the Injection on your own & for longer period than recommended by doctor.

## How To Take The Zyfoss 4 Mg Injection (Zoledronic Acid):

Zyfoss 4 mg Injection should be taken at a fixed time as directed by your doctor. Your doctor or nurse will give you Zyfoss 4 mg Injection. Kindly do not self administer this medicine.

## For How Long Should You Continue Using Zyfoss 4 Mg Injection (Zoledronic Acid):

You are always advised to take Zyfoss 4 mg Injection as prescribed. Do not start/stop using this medicine yourself. You must strictly follow all the directions given by your doctor. You must not take the Injection in larger or smaller quantity or for longer period than suggested by your doctor.

## Overdose :

You must seek out medical emergency treatment and/ or contact your surgeon without delay in case of any overdose symptoms. Since Zyfoss 4 mg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency measure will be initiated without delay by your physician if they observe overdose symptoms.

## Missed Dose:

The missed dosage of the injection should be administered by the medical doctor as soon as possible. It is strictly recommended to skip the missed dosage if it is already time for your next planned dosage. You must not double the dosage of the treatment to make up for the missed dosage. Since Zyfoss 4 mg Injection is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dosage is very low.

## What Are The Side Effects Of The Zyfoss 4 Mg Injection (Zoledronic Acid):

Hypersensitivity

Redness or swelling of eyes

Abdominal and stomach pain

Nausea and vomiting

Heartburn

Difficulty with swallowing

Irregular heartbeat

Loss of appetite

Trouble sleeping

Headache

Back pain

Musculoskeletal (bone, muscle or joint) pain

Indigestion

Diarrhea

## What Are The Common Drug Interactions:

Few medicines have been reported to interact with Zyfoss 4 mg Injection. These interactions may generate some needless or adverse effects and/or cause your drug not to work properly. You must always have a conversation with your doctor if you are taking other prescription/ Supplements so that well planned medication can be given. It interacts with the following medicines:

Magnesium Hydroxide

Nimesulide

Amikacin

Tobramycin

Zinc

Gentamicin

Iron

Deferasirox

Immunosuppressants

Contrast media

Cidofovir

It can also interact with following disease condition:

Osteonecrosis of the jaw (ONJ)

Hypocalcemia

Renal Dysfunction

Asthma

## Warning And Precaution:

Zyfoss 4 mg Injection can worsen the conditions like:

Allergy

Kidney/ Liver disease

Zyfoss 4 mg Injection is not recommended for use in children under 18 years of age

You must drink plenty of fluids to prevent dehydration & kidney damage

You of this medicine can lower the level of calcium in the blood, so you must take calcium & vitamin D supplements as suggested by your doctor

You must have regular dental check-ups & inform your doctor if you develop sudden pain in your jaw as it may cause a rare condition called osteonecrosis of the jaw

Your doctor will monitor your response to this medicine by testing your bone mineral density (BMD)

You must not take this medicine if you are pregnant, planning to conceive or breastfeeding

You must not drive or operate heavy machinery at the same time as taking this medicine as it may cause dizziness

Always consult with your medical doctor straight away to get best possible treatment if you are observing any of the above mentioned conditions.

## Things To Remember:

Keep the Zyfoss 4 mg Injection out of reach and sight of the children

This medicine is strictly used with caution for treatment of children and adolescent

Zyfoss 4 mg Injection is not recommended for use in pregnant women due to the increased risk of harmful effects on the unborn baby

You must always check up the information in particular written on the leaflet/ insert of the medicine

Always consult with your medical doctor if you have any uncertainty in case of the dosage, time & strength of the medicine.

## Indications :

Zyfoss 4 mg Injection should be taken for cancer treatment. Do not take this prescription for longer period than suggested by the medical doctor.

## Storage :

Store the Zyfoss 4 mg Injection at room temperature in dark and dry place. Make sure the Injection is intact & not damaged while purchasing or storing.