Sifasi HP 5000 IU Injection (Choriogonadotropin alfa)
Price range: $93.12 through $201.81Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 3 Injection | $93.12 | $31.04 / injection | ||
| 6 Injection | $151.56 | $25.26 / injection | ||
| 9 Injection | $201.81 | $22.42 / injection |
About Sifasi HP 5000 IU Injection (Choriogonadotropin alfa)
Medicine information
- Active ingredient
- Human chorionic gonadotrophin (hCG)
- Indication
- Sifasi HP 5000 IU is indicated for anovulatory infertility in females and for hypogonadotrophic hypogonadism, sterility associated with deficient spermatogenesis, and cryptorchidism in males. The manufacturer's product information also lists threatened and habitual abortion among its indications.
- Manufacturer
- Serum Institute of India Pvt. Ltd.
- Packaging
- Box containing 1 ampoule of lyophilized Sifasi 5000 IU and 1 ampoule of sodium chloride solvent.
- Strength
- 5000 IU
- Dosage form
- Lyophilized powder for injection with sodium chloride solvent
- Route
- Subcutaneous or intramuscular injection
Medicine overview
Sifasi HP 5000 IU Injection contains highly purified human chorionic gonadotrophin (hCG), a gonadotrophin hormone used in fertility and reproductive hormone treatment. Despite the product description supplied in the request, the manufacturer identifies Sifasi as highly purified human chorionic gonadotrophin rather than recombinant choriogonadotropin alfa. The 5000 IU product is supplied as a lyophilized powder with solvent and is given by subcutaneous or intramuscular injection after reconstitution. It is a prescription medicine requiring medical supervision.
What it is used for
In women, hCG can be used to trigger ovulation as part of appropriately monitored fertility treatment for anovulatory infertility. In males, Sifasi is used in selected cases of hypogonadotrophic hypogonadism and impaired sperm production, and it may be used for cryptorchidism where there is no anatomical obstruction. The exact reason for treatment determines how and when the injection is administered.
How it works
Human chorionic gonadotrophin has biological activity similar to luteinizing hormone (LH), one of the body's reproductive hormones. In women, an hCG surge can act like the natural mid-cycle LH surge and trigger final follicular maturation and ovulation. In males, hCG stimulates Leydig cells in the testes to produce androgens such as testosterone. These hormonal effects explain its use in selected female infertility and male hypogonadotrophic conditions.
How it is taken
Sifasi HP is administered by subcutaneous or intramuscular injection. The lyophilized powder should be reconstituted with the supplied solvent just before use. The manufacturer specifies that dosage is as directed by the physician; timing and treatment schedules therefore depend on the indication and clinical monitoring. Fertility treatment with hCG should be supervised by a clinician experienced in infertility management.
Important warnings
Do not use hCG in someone with a previous serious hypersensitivity reaction to hCG. Important contraindications and precautions for hCG therapy include certain hormone-dependent cancers and, depending on the indication, uncontrolled endocrine disorders. In women receiving ovarian stimulation, hCG can precipitate ovarian hyperstimulation syndrome (OHSS), which may become severe and can involve marked ovarian enlargement, fluid accumulation, breathing problems and thromboembolic events. Multiple pregnancy and ovarian torsion are additional fertility-treatment risks. Severe pelvic or abdominal pain, rapid weight gain, persistent vomiting, reduced urination, breathing difficulty, chest pain, leg swelling, or symptoms of a serious allergic reaction require prompt medical assessment. hCG can cause fluid retention and warrants caution in people with cardiac or renal disease, hypertension, epilepsy, migraine or asthma.
Side effects and monitoring
Common or reported effects of hCG therapy include headache, fatigue and injection-site reactions such as pain, redness, bruising, swelling or itching. Women may experience abdominal discomfort, nausea, diarrhea, ovarian enlargement or ovarian cysts, particularly in association with ovarian stimulation. Serious effects include severe OHSS, thromboembolism, ovarian torsion and severe hypersensitivity reactions. In males, fluid retention and gynecomastia can occur, and hCG may cause precocious puberty in susceptible children. During ovulation induction, ovarian response is generally monitored with ultrasound, often together with serum estradiol measurements, to guide treatment and reduce the risk of excessive ovarian stimulation.
Pregnancy
hCG used for ovulation induction is intended to help establish pregnancy, but ongoing hCG treatment is not generally indicated after pregnancy has been confirmed unless a clinician has prescribed it for a specific purpose. Authoritative hCG labeling notes that there are limited data on hCG administration during established pregnancy.
Breastfeeding
It is not known whether human chorionic gonadotrophin is excreted in human milk. Breastfeeding patients should discuss treatment with their clinician so the need for hCG and potential risks to the breastfed child can be considered.
Storage
Store refrigerated at 2°C to 8°C and do not freeze. Product-specific retail records for Sifasi HP 5000 IU identify refrigerated storage; follow the pack instructions for handling after reconstitution.
Frequently asked questions
Why do I need an hCG injection during fertility treatment?
In appropriate fertility treatment, hCG acts similarly to the body's natural LH surge and can trigger final follicular maturation and ovulation. The timing is important and is determined from your treatment plan and ovarian monitoring.
How soon after Sifasi HP will ovulation happen?
The exact timing for an individual patient should come from the fertility clinic managing the treatment. Do not change the timing of intercourse, insemination, egg retrieval, or another fertility procedure without the clinic's instructions.
Can Sifasi HP cause a false-positive pregnancy test?
Yes. Pregnancy tests detect hCG, so an hCG fertility injection can temporarily interfere with urine or blood pregnancy testing. Follow the testing date given by your fertility clinic rather than testing earlier on your own.
What symptoms of ovarian hyperstimulation should I watch for?
Seek prompt medical advice for severe or worsening pelvic or abdominal pain, rapid weight gain, persistent nausea or vomiting, reduced urination, marked abdominal swelling, or breathing difficulty. These can be warning signs of OHSS after ovarian stimulation.
Can Sifasi HP be injected under the skin?
Yes. The manufacturer states that Sifasi may be administered by subcutaneous or intramuscular injection. Use only the route and injection technique instructed by your healthcare professional.
Does Sifasi HP contain recombinant choriogonadotropin alfa?
The manufacturer's current Sifasi information identifies the ingredient as highly purified human chorionic gonadotrophin for injection. It does not identify Sifasi HP as a recombinant choriogonadotropin alfa product.
Does the injection need to be mixed before use?
Yes. The manufacturer's Sifasi 5000 IU presentation contains lyophilized hCG and a separate sodium chloride solvent, and the powder is reconstituted before administration.
Can I use a home pregnancy test soon after an hCG trigger injection?
The injection itself can be detected by an hCG pregnancy test and may produce a positive result before a pregnancy can reliably be confirmed. Use the testing schedule provided by your fertility clinic.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Indication | hCG helps increase Testosterone production and sperm count in men, treating conditions like Oligospermia (low sperm count) and Cryptorchidism (undescended testes). |
|---|---|
| Packaging | Qty |
| Delivery Time | 6 To 15 days |
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