Resimat 400 Mg Tablet

Dr. Emily Brown

Dr. Ryan Mitchell

SKU

CMS5194

USA Brand Name

Gleevec

Strength

400mg

Generic Name

Imatinib mesylate (400Mg)

Manufacturer

Resonance Laboratories Pvt Ltd

## Resimat 400 Mg Tablet (Imatinib Mesylate)

## What Is The Generic Name For Resimat 400 Mg Tablet:

Imatinib Mesylate is the generic version for Resimat 400 mg Tablet

## Which US Brand is Equivalent To Resimat 400 Mg Tablet (Imatinib Mesylate):

Gleevec

## About Resimat 400 Mg Tablet (Imatinib Mesylate)

Resimat 400 mg Tablet contains an active ingredient, Imatinib Mesylate, which belongs to the class of medicines known as tyrosine kinase inhibitors.  This medicine is used in the treatment of blood cancer (chronic myeloid leukemia & Acute lymphocytic leukemia) and also gastrointestinal stromal tumors. Leukemia is the cancer of the WBCs or white blood cells. WBCs or White blood cells help the body fight infection. The blood cells form in the bone marrow. In leukemia, the bone marrow produces nonstandard white blood cells. These cells outnumber the healthy blood cells, making it hard for blood to do its work. In chronic myeloid leukemia (CML), there are excessive granulocytes, a type of white blood cell. The majority of people having CML have a gene mutation (change) known as the Philadelphia chromosome. A Gastrointestinal stromal tumor (GISTs) is the tumor of the gut. The special cells in the wall of the gut start to grow out of control. The tumors could be malignant (spread to other areas of the body) or benign (do not spread to other areas of the body). This medicine is readily available with all the leading primary pharmacies, drugstores, and medical supply stores; however, this medication should be taken on doctor’s recommendation only.

## Manufacturer :

Resonance Laboratories Pvt. Ltd. is the primary pharmaceutical company that manufactures Resimat 400 mg Tablet.

## Strength :

Resimat 400 mg Tablet contains an active constituent, Imatinib Mesylate (400 mg). This medicine is readily available with all the leading primary pharmacies, drugstores, and medical supply stores.

## What Are The Uses Of The Resimat 400 Mg Tablet (Imatinib Mesylate):

Resimat 400 mg Tablet is used for the treatment in the following conditions:

Chronic myelogenous leukemia (CML)

Acute lymphoblastic Leukemia (ALL)

Myeloproliferative disorder

Myelodysplastic disease

Systemic mastocytosis

Hypereosinophilic syndrome

Chronic eosinophilic leukemia

Dermatofibrosarcoma protuberans

Gastrointestinal stromal tumor

## How Resimat 400 Mg Tablet (Imatinib Mesylate) Works:

Resimat 400 mg Tablet has an active ingredient, Imatinib Mesylate, which is an anti-cancer medication . A protein enzyme, a bcr-abl tyrosine kinase that is responsible for the growth of abnormal proliferation of cancer cells. This medicine inhibits the proliferation & induces apoptosis (planned cell death) in bcr-abl positive cells (cancer cells). This is how it acts to stop or slow the spread of cancer.

## Before You Use Resimat 400 Mg Tablet (Imatinib Mesylate):

Make certain that:

You are not having some severe Disease

You are not sensitive to Imatinib Mesylate

You should update your doctor vis-à-vis your medical histories like your pre-existing disease, Medications & surgeries, supplements, Food Habits, lifestyle, and the rest.

## What Should You Avoid While Taking Resimat 400 Mg Tablet (Imatinib Mesylate):

You should avoid driving

You should avoid taking alcohol

You should avoid smoking

You should avoid taking Medicines without prescription

## When Not To Use Resimat 400 Mg Tablet (Imatinib Mesylate):

You should not take Resimat 400 mg Tablet if you:

Have ever noticed any Allergy/Hypersensitivity

Have liver problems

Have kidney problems

Have gastrointestinal disorders

Have Hypothyroidism

Are receiving a live attenuated vaccine

Have Heart and blood vessel disorder

Are suffering from Fluid retention and edema

Have internal bleeding or hemorrhage

Are pregnant

Have infections

Are breastfeeding

## Tell Your Doctor If You:

Have an Allergy to the Tablet

Are taking Alcohol or Other Drugs

Have Liver/ Kidney disease

Have infections

## Dosage :

Resimat 400 mg Tablet contains an active ingredient, Imatinib Mesylate, that is used in the treatment of blood cancer (chronic myeloid leukemia & Acute lymphocytic leukemia) and also gastrointestinal stromal tumor.  This medicine is readily available with all the leading primary pharmacies, drugstores, and medical supply stores; however, this medication should be taken on doctor’s recommendation only. The patient should discuss with the medical doctor for an alteration of dosage and time of the medicine, knowing the fact that the severity of the disease varies from person to person. This adjustment can only be judged optimal by your doctor.

Adults are advised to take Resimat 400 mg Tablet at a fixed time with food as instructed by your medical doctor. You must take Resimat 400 mg Tablet regularly on time for better results.

## How Much Of The Resimat 400 Mg Tablet (Imatinib Mesylate) to Be Used:

Resimat 400 mg Tablet is readily available in various strengths and substitutes. Patients are regularly suggested to pursue doctor’s prescriptions & instructions to take Resimat 400 mg Tablet. You should not receive this Tablet on your own & for a more extended period as recommended by the doctor.

## How To Take The Resimat 400 Mg Tablet (Imatinib Mesylate):

Take Resimat 400 mg Tablet in the dose and duration as recommended by your doctor of medicine. You have to take the medicine as a whole & not chew, crush, or break the Tablet. Resimat 400 mg Tablet must be taken with food; however, it is always better to take this medicine at a set occasion.

## For How Long Should You Continue Using Resimat 400 Mg Tablet (Imatinib Mesylate):

You are always suggested to take Resimat 400 mg Tablet as prescribed. You should not stop or start taking this medication all of a sudden on your own. You have to follow all the procedures given by your doctor carefully. You must not obtain the Tablet in a larger or smaller measure or for an extended period than recommended by the doctor.

## Overdose :

You must search for medical emergency treatment and get in touch with your medical doctor straight away in the situation of any overdose symptoms. The emergency treatment will be started without any delay by your medical doctor if they notice any overdose symptoms in you.

## Missed Dose:

The missed dose of the Tablet has to be taken as fast as viable. You should firmly skip out the missed dose if it is the time for your next planned dosage by now. It is strictly recommended not to double the dosage of the treatment to make up for the missed dose.

## What Are The Side Effects Of The Resimat 400 Mg Tablet (Imatinib Mesylate):

Diarrhea

Nausea and Vomiting

Mouth sores

Loss of appetite

Altered sense of taste

Heartburn and indigestion

Joint pain, stiffness, and swelling

Burning or tingling sensation of skin

Difficulty in falling or staying asleep

Skin rash, hives, or itching

Hair loss or thinning of the hair

Swelling around the eyes

Swelling of the hands, feet, ankle, and lower legs

Severe breathing difficulty

Fast/irregular heartbeat

Presence of blood in cough

Yellowing of skin and eyes

Unusual bleeding or bruising

Abdominal pain or bloating

Bloody stool

## What Are The Common Drug Interactions:

Many of the medicines have been reported to interact with Resimat 400 mg Tablet. These interactions may engender some unwanted or unfavorable effects, or it may probably cause your drug not to function correctly. You should often have a conversation with your doctor if you are taking other prescription/ Supplements; consequently, well-proposed medication can be given. It interacts with the following medicines:

Atorvastatin

Carbamazepine

Fluvastatin

Lovastatin

Cisapride

Clarithromycin

Erythromycin

Ketoconazole

Pimozide

Warfarin

Colchicine

Phenobarbital

BCG vaccine

Dexamethasone

Etanercept

This medicine can as well interact with the following mentioned disease condition:

Infections

Heart and blood vessel disorder

Fluid Retention and edema

Bone marrow suppression

Kidney disease

Liver Disease

You must not take grapefruit or grapefruit juice during treatment with this medicine due to the increased risk of severe adverse effects

## Warning And Precaution:

Resimat 400 mg Tablet can worsen the conditions like:

Kidney/ Liver disease

Allergy

Infections

This drug is not recommended for use by elderly patients

You must get your blood test done repeatedly during treatment to monitor the side effects of Imatinib Mesylate on your blood cells

Regular blood tests are essential to check your blood cells along with kidney, liver & heart function during treatment with this medicine

Use of reliable, effective contraception by both males & females during treatment is essential to avoid pregnancy

You should not drive or operate heavy machines besides taking this medicine as it may cause dizziness

You are supposed not to take this drug if you are pregnant, planning to conceive or are breastfeeding

You must always discuss with your medical doctor to obtain the first-rate treatment if you are observing a number of the conditions mentioned above.

## Things To Remember:

Keep the Resimat 400 mg Tablet out of reach & vision of the children

This treatment is strictly used with care for the treatment of elderly

Resimat 400 mg Tablet is not recommended for use by pregnant women due to the augmented risk of detrimental effects on the unborn child

You have to always check up the information in predominantly printed on the leaflet/ insert of the medicine

You must continuously discuss with your medical doctor if you have any uncertainty in terms of the dosage, strength & time of the drug.

## Indications :

Resimat 400 mg Tablet should be used as recommended by your doctor. You must not take this drug for a more extended period than prescribed by the medical doctor.

## Storage :

Store the Resimat 400 mg Tablet at room temperature in dark & dry location. Make sure that the Tablet is intact & not broken while purchasing or storing.