Penegra 50 Mg (Sildenafil Citrate)

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Pack SizePriceUnit PriceQuantity 
40 Tablet/s$134.59$3.36 / tablet
80 Tablet/s$231.44$2.89 / tablet
120 Tablet/s$314.72$2.62 / tablet
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Estimated delivery: October 9, 2026 – October 14, 2026
Written by Dr Ambrose Chan, MD, MD Medically reviewed by Dr. Sabrina Castillon, MD, MD
Last updated on September 14, 2026
Description

About Penegra 50 Mg (Sildenafil Citrate)

Medicine information

Active ingredient
Sildenafil citrate
Delivery time
10-14 business days after dispatch for the United States, United Kingdom, Canada, and Australia; estimates may be extended by customs or local carrier delays.
Indication
Erectile dysfunction in adult men
Manufacturer
Zydus Healthcare Limited
Packaging
Blister strip of 4 tablets
Strength
50 mg
Dosage form
Tablet
Route
Oral

Medicine overview

Penegra 50 mg is an oral sildenafil medicine used to treat erectile dysfunction in adult men. Each tablet provides 50 mg of sildenafil and belongs to the phosphodiesterase type 5 (PDE5) inhibitor class. Sildenafil improves the normal erectile response by increasing blood flow to the penis during sexual stimulation. Sexual stimulation is still required for the medicine to work, and sildenafil does not increase sexual desire or cure the underlying cause of erectile dysfunction.

What it is used for

Penegra 50 mg is used for erectile dysfunction, a condition in which a man has difficulty getting or maintaining an erection suitable for sexual activity. Sildenafil can improve the ability to achieve and maintain an erection when sexual stimulation occurs. The medicine does not protect against sexually transmitted infections and is not a contraceptive.

How it works

Sildenafil inhibits phosphodiesterase type 5 (PDE5), an enzyme involved in breaking down cyclic guanosine monophosphate (cGMP). During sexual stimulation, nitric oxide increases cGMP in erectile tissue. By slowing its breakdown, sildenafil supports relaxation of smooth muscle and increased blood flow into the penis. This strengthens the natural erectile response to sexual stimulation; it does not produce an erection independently of sexual arousal.

How it is taken

Penegra 50 mg is taken by mouth as directed by the prescriber. For erectile dysfunction, sildenafil is generally taken as needed approximately 1 hour before sexual activity and may be taken from 30 minutes to 4 hours beforehand. It can be taken with or without food, although a high-fat or large meal may delay its effect. Sildenafil should not be taken more than once in 24 hours unless specifically directed otherwise by the prescriber.

Important warnings

Do not use sildenafil with nitrates or nitric oxide donors, including nitroglycerin, isosorbide medicines, or recreational “poppers,” because the combination can cause a dangerous fall in blood pressure. It is also contraindicated with guanylate cyclase stimulators such as riociguat and in people with hypersensitivity to sildenafil. Medical assessment is particularly important for people with significant cardiovascular disease, very low or uncontrolled high blood pressure, recent heart attack or stroke, severe liver or kidney impairment, bleeding disorders, active peptic ulcer, retinal disease, previous non-arteritic anterior ischemic optic neuropathy (NAION), penile deformity, or conditions that increase the risk of priapism. Alpha-blockers, blood-pressure medicines, strong CYP3A4 inhibitors and ritonavir can interact with sildenafil. Combining it with another PDE5 inhibitor or another sildenafil-containing treatment is not recommended. Seek urgent medical care for an erection lasting longer than 4 hours, sudden loss or marked reduction of vision or hearing, or chest pain, severe dizziness or fainting associated with sexual activity.

Side effects and monitoring

Common effects include headache, flushing, indigestion, nasal congestion, dizziness, nausea, back or muscle pain, rash and temporary visual changes such as blurred vision or altered colour perception. Serious but less common risks include prolonged erection or priapism, severe hypotension, sudden vision loss associated with NAION, sudden decrease or loss of hearing, and serious cardiovascular events in susceptible patients. An erection lasting more than 4 hours requires emergency treatment. Sudden vision or hearing loss also requires prompt medical attention. Routine laboratory monitoring is not generally required solely because sildenafil is being used for erectile dysfunction, but cardiovascular health and interacting medicines should be assessed when clinically appropriate.

Pregnancy

Penegra 50 mg for erectile dysfunction is not indicated for use in women. Sildenafil erectile-dysfunction labeling does not provide adequate human pregnancy data to establish drug-associated developmental risk.

Breastfeeding

Penegra 50 mg for erectile dysfunction is not indicated for use in women. Sildenafil and its active metabolite have been reported in human milk, but available data are insufficient to determine effects on a breastfed infant or milk production.

Food, drink and interactions

Sildenafil 50 mg did not increase the blood-pressure-lowering effect of a moderate alcohol dose in a controlled interaction study in healthy volunteers. However, drinking excessive alcohol can make it harder to achieve an erection and may contribute to dizziness or other unwanted effects, so heavy alcohol intake should be avoided when using sildenafil.

Food and drink

Sildenafil can be taken with or without food. A high-fat or large meal can delay absorption and may make the medicine take longer to work. Grapefruit or grapefruit juice can affect sildenafil metabolism and may increase the likelihood of side effects, so patients should check with their prescriber or pharmacist before combining them.

Storage

Store at controlled room temperature, approximately 20°C to 25°C (68°F to 77°F), and keep the tablets out of the reach of children. Follow any additional storage instructions printed on the Penegra package.

Frequently asked questions

Do I need to be sexually aroused for Penegra 50 mg to work?

Yes. Sildenafil supports the physical erectile response to sexual stimulation; it does not automatically cause an erection or increase sexual desire.

How long before sex should sildenafil 50 mg be taken?

Sildenafil is generally taken about 1 hour before sexual activity, although it may be taken from 30 minutes to 4 hours beforehand. Follow the timing prescribed for you.

Why does Penegra sometimes seem slower after a meal?

A high-fat or large meal can delay sildenafil absorption, so it may take longer to produce its effect.

Can I take another Penegra tablet if the first one does not work?

Do not take extra tablets on your own. Sildenafil for erectile dysfunction should not normally be taken more than once in 24 hours, and treatment changes should be discussed with the prescriber.

What should I do if I get a headache after taking sildenafil?

Headache is a common sildenafil side effect. If it is severe, persistent, or accompanied by concerning symptoms such as chest pain, fainting, or sudden vision changes, obtain medical advice promptly.

What happens if an erection lasts more than 4 hours?

Seek emergency medical care immediately. A prolonged erection can damage penile tissue if it is not treated promptly.

Can I take Penegra with nitroglycerin or other nitrate medicines?

No. Sildenafil must not be combined with nitrates or nitric oxide donors because blood pressure can fall to a dangerous level.

Can Cheap Generic Med ship Penegra to the United States?

Cheap Generic Med serves the United States under its international shipping model. Delivery is typically estimated at 10-14 business days after dispatch, although customs or carrier delays can extend transit; prescription and personal-import requirements may also apply.

Will my Cheap Generic Med order have tracking?

Tracked international shipping is used under the standard fulfilment model. A tracking number should be provided after dispatch, although the carrier system may take 24-72 hours to begin showing movement.

Sources

  1. www.zydushealthcare.com
  2. www.dailymed.nlm.nih.gov
  3. medlineplus.gov
  4. www.nhs.uk
  5. www.nda.or.ug

Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.

Additional information
Active IngredientsSildenafil Citrate
ManufacturerZydus Cadila
PackagingQty
strength50mg
Delivery Time6 To 15 days
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