PAH 20 Mg Tablet (Sildenafil Citrate)
Price range: $86.18 through $131.95Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 60 Tablet/s | $86.18 | $1.44 / tablet | ||
| 90 Tablet/s | $111.14 | $1.23 / tablet | ||
| 120 Tablet/s | $131.95 | $1.10 / tablet |
About PAH 20 Mg Tablet (Sildenafil Citrate)
Medicine information
- Active ingredient
- Sildenafil citrate
- Delivery time
- Typically 10–14 business days after dispatch to the United States, United Kingdom, Canada, and Australia; 12–18 business days to listed European destinations; and 14–21 business days to other listed destinations. These are estimates and customs or local carrier delays may extend delivery.
- Indication
- Pulmonary arterial hypertension (PAH), WHO Group I, in adults, to improve exercise ability and delay clinical worsening.
- Manufacturer
- MSN Laboratories Pvt Ltd
- Strength
- 20 mg
- Dosage form
- Tablet
- Route
- Oral
Medicine overview
PAH 20 Mg Tablet contains sildenafil citrate equivalent to 20 mg of sildenafil. MSN Laboratories identifies PAH-20 as a sildenafil 20 mg product for symptomatic pulmonary arterial hypertension. Sildenafil belongs to the phosphodiesterase type 5 (PDE5) inhibitor class. In PAH, it relaxes blood vessels in the lungs, helping reduce resistance to blood flow through the pulmonary circulation. Sildenafil 20 mg tablets are used in adults with WHO Group I PAH to improve exercise ability and delay clinical worsening.
What it is used for
PAH 20 Mg Tablet is used for pulmonary arterial hypertension, a condition in which pressure is abnormally high in the arteries supplying the lungs. Sildenafil 20 mg therapy is indicated in adults with WHO Group I PAH to improve exercise capacity and help delay clinical worsening. PAH-specific sildenafil treatment should be distinguished from sildenafil products and strengths used for erectile dysfunction.
How it works
Sildenafil inhibits phosphodiesterase type 5 (PDE5), an enzyme that breaks down cyclic guanosine monophosphate (cGMP). Increasing cGMP in pulmonary vascular smooth muscle allows these muscles to relax. This widens blood vessels in the lungs and reduces pulmonary vascular resistance, making it easier for blood to move through the pulmonary circulation. Sildenafil can also cause some widening of blood vessels elsewhere in the body, which explains its potential to lower systemic blood pressure.
How it is taken
PAH 20 Mg Tablet is taken by mouth. For sildenafil 20 mg tablets used for PAH in adults, authoritative prescribing information specifies 20 mg three times daily; some labels specify doses approximately 4–6 hours apart. Take the medicine according to the prescribing clinician's instructions. Do not combine it with Viagra or another sildenafil/PDE5-inhibitor product unless specifically directed by the treating clinician. Do not independently increase, reduce, or discontinue PAH treatment.
Important warnings
Do not use sildenafil with organic nitrates such as nitroglycerin or isosorbide medicines, or with riociguat, because blood pressure can fall to an unsafe level. It must also not be used in people with known hypersensitivity to sildenafil or tablet ingredients. Caution is needed with low blood pressure, fluid depletion, antihypertensive medicines, severe left ventricular outflow obstruction, bleeding disorders or active peptic ulcer, and certain eye conditions. Strong CYP3A inhibitors are not recommended with PAH sildenafil, while CYP3A inducers can alter sildenafil exposure. Sildenafil is not recommended in pulmonary veno-occlusive disease because pulmonary edema may occur. Seek prompt medical attention for sudden vision or hearing loss and immediate care for an erection lasting more than 4 hours. Sildenafil for pulmonary hypertension secondary to sickle cell disease has been associated with serious vaso-occlusive crises.
Side effects and monitoring
Common effects reported with sildenafil in adults treated for PAH include headache, flushing, indigestion, back pain, limb pain, muscle pain, and diarrhea. Edema has also occurred when sildenafil was used with intravenous epoprostenol. Serious or less common concerns include symptomatic low blood pressure, sudden vision loss, sudden decrease or loss of hearing, prolonged erection, allergic reactions, and pulmonary edema in patients with possible pulmonary veno-occlusive disease. Blood pressure should be monitored when sildenafil is used with other blood-pressure-lowering medicines. Sudden vision or hearing changes, fainting or severe hypotensive symptoms, breathing that rapidly worsens, or an erection lasting more than 4 hours requires prompt medical assessment.
Pregnancy
Available human data have not shown a clear association between sildenafil use during pregnancy and major birth defects, miscarriage, or adverse maternal or fetal outcomes, but the available evidence is limited. Untreated pulmonary arterial hypertension itself carries substantial maternal and fetal risks, including heart failure, stroke, premature delivery, and death. Treatment during pregnancy therefore requires specialist medical assessment rather than starting or stopping sildenafil without clinical supervision.
Breastfeeding
Sildenafil and its active metabolite have been detected in human breast milk. Available information is insufficient to determine the effects on a breastfed infant or on milk production. A clinician should assess breastfeeding and treatment in the context of the mother's need for PAH therapy.
Food, drink and interactions
Alcohol can contribute to dizziness and blood-pressure lowering. Because sildenafil also has vasodilating effects, avoid excessive alcohol and discuss alcohol use with the treating clinician, particularly if dizziness or low blood pressure occurs.
Food and drink
Sildenafil tablets may be taken with or without food. Grapefruit or grapefruit juice can affect sildenafil metabolism and may increase the likelihood of adverse effects, so avoiding grapefruit is prudent while taking sildenafil.
Storage
Store below 25°C.
Frequently asked questions
Is sildenafil 20 mg for PAH the same treatment as sildenafil for erectile dysfunction?
The active drug is sildenafil, but the indication and dosing regimen are different. PAH 20 Mg Tablet is a 20 mg product intended for pulmonary arterial hypertension, so it should be used according to the PAH prescription rather than an erectile-dysfunction dosing regimen.
Can sildenafil for PAH lower my blood pressure?
Yes. Sildenafil widens blood vessels and can cause a mild or sometimes clinically important fall in blood pressure. The risk is particularly important with other blood-pressure-lowering medicines and is why nitrates and riociguat must not be combined with sildenafil.
Can I take PAH 20 Mg Tablet with Viagra or another PDE5 inhibitor?
No, not unless a specialist has specifically directed otherwise. Sildenafil PAH labeling advises patients not to combine it with Viagra or other PDE5 inhibitors because the safety and effectiveness of these combinations have not been established.
Can I take sildenafil 20 mg with nitrates?
No. Organic nitrates, including nitroglycerin and isosorbide medicines, are contraindicated with sildenafil because the combination can cause a dangerous fall in blood pressure.
What should I do if I suddenly notice changes in my vision or hearing?
Seek prompt medical attention. Sudden loss of vision or a sudden decrease or loss of hearing has been reported with PDE5 inhibitors, including sildenafil.
Can PAH 20 Mg Tablet be taken with food?
Yes. Sildenafil tablets can generally be taken with or without food. Follow the prescribed timing consistently and avoid grapefruit or grapefruit juice because it can affect sildenafil metabolism.
Why do I need to keep taking sildenafil when I do not feel an immediate effect?
PAH sildenafil is used as ongoing treatment to improve exercise ability and help delay clinical worsening; it is not intended only for immediate symptom relief. Do not stop or change prescribed PAH therapy without speaking with the clinician managing the condition.
Will Cheap Generic Med provide tracking for an international PAH 20 Mg Tablet order?
Under the standard fulfilment model, tracked international shipping is used and a tracking number should be provided after dispatch. New tracking information may take 24–72 hours to appear in the carrier system.
Is international delivery guaranteed within the estimated time?
No. Delivery ranges are estimates rather than guaranteed arrival dates. Customs inspections, import requirements, and destination postal delays can extend transit, and shipping availability does not by itself establish that personal import is lawful in a particular country.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Active Ingredients | Sildenafil Citrate |
|---|---|
| Manufacturer | Msn Laboratories |
| Packaging | Qty |
| strength | 20mg |
| Delivery Time | 6 To 15 days |
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