Nataprove Eye Drop 5ml

Dr. Emily Brown

Dr. Ryan Mitchell

## What is Nataprove Eye Drop

Nataprove Eye Drop is an ophthalmic antifungal suspension used to treat fungal eye infections, primarily Fungal Keratitis (a fungal infection of the cornea), Fungal Blepharitis (infection of the eyelid margins), and Fungal Conjunctivitis (infection of the conjunctiva, the clear tissue covering the white of the eye). It is manufactured by Johnlee Pharmaceuticals Pvt Ltd in GMP-compliant facilities.

It contains FDA-approved Natamycin (5%) as its active ingredient, a polyene macrolide antifungal. Natamycin works by binding to Ergosterol, the main structural component of fungal cell membranes. This binding creates a barrier that inhibits nutrient transport, prevents fungal growth, and leads to cell death.

Nataprove Eye Drop is instilled as 1 drop into the affected eye every 1-2 hours during the first few days, then reduced to every 3-4 hours as the infection responds, or as directed by an ophthalmologist. Treatment is typically continued for 6 weeks or until clinical resolution is confirmed.

Side effects of Natamycin are generally mild and localized to the eye, including temporary stinging, burning, or blurring of vision after administration. Before using the eye drops, inform a doctor about any known hypersensitivity to Natamycin or any component of the formulation.

This eye drop is for ophthalmic use only and must not be ingested or applied to other areas of the body. Store it below 25°C, protected from light. Keep the bottle tightly closed and out of reach of children.

## What are the benefits of using Nataprove Eye Drop

Natamycin works by binding to Ergosterol in the fungal cell membrane, disrupting membrane function and inhibiting fungal growth, leading to fungal cell death. It is selective in its antifungal action without harming surrounding ocular tissue.

Nataprove Eye Drop is effective in treating fungal eye infections such as:

Fungal Keratitis

Fungal Blepharitis

Fungal Conjunctivitis

## How to use Nataprove Eye Drop

Nataprove Eye Drop is a prescription medication that should be used as directed by an ophthalmologist or healthcare professional. Here are the general guidelines :

Instill 1 drop into the affected eye every 1-2 hours during waking hours for the initial days of treatment, then reduce to every 3-4 hours as directed by a doctor as the infection responds.

Wash your hands thoroughly before each application. Tilt the head back, pull down the lower eyelid, and instill the drop into the conjunctival sac (the pocket between the eyelid and the eye). Close the eye gently for 1-2 minutes after instillation.

Shake the bottle well before each use, as Natamycin is a suspension and settles on standing.

Do not touch the dropper tip to any surface to prevent contamination. Do not wear contact lenses during Natamycin treatment unless specifically advised by a doctor.

## Strengths and Substitutes

Nataprove Eye Drops are available in a single strength formulation. However, you can consider the following alternatives available at Cheap Medicine Shop:

View all substitutes

## What are the side effects of Nataprove Eye Drop

While generally well-tolerated, Nataprove Eye Drop can cause some mild side effects in the eye. These generally resolve without treatment. However, consult a healthcare professional if they persist or significantly affect vision:

Temporary stinging or burning immediately after instillation

Blurred vision shortly after application

Eye redness or irritation

Sensitivity to light

Mild swelling of the eyelid

Foreign body sensation in the eye

## Safety Advice

Liver Disease

Nataprove Eye Drop is applied directly to the eye with negligible systemic absorption at standard ophthalmic doses. Liver disease does not affect the safety or effectiveness for ocular use. Inform a doctor of any significant health conditions before starting treatment, particularly if concurrent systemic antifungal therapy is also being considered.

Kidney Impairment

As an ophthalmic suspension with very limited systemic absorption, Nataprove Eye Drop does not affect kidney function under normal conditions of use. Kidney disease does not generally affect its suitability for treating fungal eye infections. Inform a doctor of any kidney conditions before use if additional systemic antifungal treatment is planned.

Pregnant and Breastfeeding women

Natamycin eye drops can be used during pregnancy and breastfeeding when clearly necessary and under medical supervision. Given the negligible systemic absorption of topically applied Natamycin in the eye, the risk to the developing baby or nursing infant is considered very low. An ophthalmologist should confirm that treatment is necessary and appropriate before initiating therapy.

Avoid

Do not use Nataprove Eye Drop in patients with known hypersensitivity to Natamycin. Do not touch the dropper tip to any surface, as contamination of the bottle can cause secondary infection. Do not wear contact lenses during treatment. Do not use it for bacterial or viral eye infections, as Natamycin has no antibacterial or antiviral activity.

## FAQs

## Can Nataprove Eye Drop treat fungal eye infections?

Yes, Nataprove Eye Drop is specifically used to treat fungal eye infections, such as Fungal Keratitis. It contains Natamycin, an antifungal medicine effective against filamentous fungi such as Fusarium and Aspergillus, which are common causes of fungal corneal infections.

## Is Nataprove Eye Drop safe for long-term use?

No, Nataprove is typically used for short-term treatment. It is generally not for long-term use. Prolonged use should be under continuous medical supervision. Do not use it beyond the recommended time to ensure safety.

## Can contact lenses be worn while using Nataprove Eye Drop?

No, contact lenses should not be worn during treatment with Nataprove. Contact lenses can interfere with the medicine’s penetration into the corneal tissue, reduce its effectiveness, and harbor fungal organisms, contributing to ongoing infection. An ophthalmologist will advise when it is safe to resume lens wear.

## What precautions should be followed while using antifungal eye drops?

Wash your hands before using Natamycin eye drops. Shake the bottle well before use and avoid touching the dropper tip to the eye or any surface. Do not wear contact lenses during treatment. Use for the full prescribed duration even if symptoms improve.

## How long does Nataprove Eye Drop take to show improvement?

Improvement in Fungal Keratitis with Natamycin therapy is gradual. Initial reduction in symptoms such as pain and discharge may be noticeable within 1-2 weeks of treatment. However, corneal infection requires a minimum treatment course of 6 weeks or as prescribed for complete fungal eradication.

## Can Nataprove Eye Drop be used for bacterial eye infections?

No, Natamycin is an antifungal agent and has no activity against bacteria or viruses. Nataprove Eye Drop is indicated specifically for fungal eye infections. Using it for Bacterial Conjunctivitis or other non-fungal infections will not be effective and may delay appropriate antibiotic treatment.

## Should Nataprove Eye Drop be shaken before use?

Yes, Nataprove Eye Drop has the active ingredient suspended in particles rather than fully dissolved. On standing, these particles settle to the bottom of the bottle. Shaking the bottle before each use redistributes the particles evenly, ensuring that each drop contains the correct concentration of Natamycin.