Megalis 20 Mg (Tadalafil)

Price range: $158.77 through $497.39Required

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Pack SizePriceUnit PriceQuantity 
20 Tablet/s$158.77$7.94 / tablet
40 Tablet/s$278.00$6.95 / tablet
80 Tablet/s$497.39$6.22 / tablet
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Estimated delivery: November 4, 2026 – November 9, 2026
Written by Dr Ambrose Chan, MD, MD Medically reviewed by Dr. Sabrina Castillon, MD, MD
Last updated on September 15, 2026
Description

About Megalis 20 Mg (Tadalafil)

Medicine information

Active ingredient
Tadalafil
Delivery time
10–14 business days after dispatch for the United States, United Kingdom, Canada, and Australia; other destinations vary under the store shipping framework. These are estimates and customs or carrier delays may extend delivery.
Indication
Erectile dysfunction (ED)
Manufacturer
Macleods Pharmaceuticals Limited
Packaging
1 strip of 4 film-coated tablets
Strength
20 mg
Dosage form
Film-coated tablet
Route
Oral

Medicine overview

Megalis 20 mg is an oral medicine containing tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor. This specific 20 mg product is manufactured by Macleods Pharmaceuticals Limited and is used for erectile dysfunction in adult men. Tadalafil supports an erection by increasing blood flow to the penis during sexual stimulation. It does not cause an erection automatically, and sexual stimulation is still required for the medicine to work.

What it is used for

Megalis 20 mg is used for the treatment of erectile dysfunction, where a man has difficulty getting or maintaining an erection suitable for sexual activity. Tadalafil as an active ingredient also has established uses in benign prostatic hyperplasia at different dosing regimens, but those indications should not be assumed to apply to this specific 20 mg Megalis presentation without appropriate prescribing guidance.

How it works

Tadalafil blocks phosphodiesterase type 5 (PDE5), an enzyme involved in breaking down cyclic guanosine monophosphate (cGMP). During sexual stimulation, nitric oxide increases cGMP in erectile tissue. By slowing its breakdown, tadalafil helps the smooth muscle and blood vessels in the penis relax, allowing increased blood flow and supporting an erection. The effect depends on sexual stimulation; tadalafil does not independently trigger sexual arousal.

How it is taken

Megalis 20 mg is swallowed by mouth. For tadalafil used as needed for erectile dysfunction, it is taken before anticipated sexual activity according to the prescriber's directions. It can be taken with or without food, and the effect may remain clinically useful for up to 36 hours after a dose. It should not be taken more than once per day. The 20 mg strength should not be treated as the standard once-daily tadalafil regimen.

Important warnings

Do not use tadalafil with nitrates such as nitroglycerin or isosorbide medicines, or with recreational nitrate products (“poppers”), because the combination can cause a dangerous fall in blood pressure. It is also contraindicated with guanylate cyclase stimulators such as riociguat. Tell the prescriber about heart disease, recent heart attack or stroke, low or uncontrolled high blood pressure, kidney or liver problems, bleeding disorders, stomach ulcers, penile deformity, or conditions that increase the risk of prolonged erections. Caution is needed with alpha-blockers, blood-pressure medicines and strong CYP3A4 inhibitors such as ketoconazole or ritonavir. Do not combine tadalafil with other PDE5 inhibitors or erectile-dysfunction treatments unless specifically directed by a clinician. Seek urgent medical attention for an erection lasting more than 4 hours, sudden loss of vision or hearing, chest pain, fainting, or a serious allergic reaction. If emergency nitrate treatment is medically necessary, healthcare professionals should know when tadalafil was last taken; prescribing information advises at least 48 hours after the last tadalafil dose before nitrate administration is considered.

Side effects and monitoring

Common effects include headache, indigestion or dyspepsia, back pain, muscle aches, flushing, and nasal congestion. Less common but potentially serious reactions include severe hypotension, prolonged erection or priapism, sudden hearing loss, sudden vision loss associated with non-arteritic anterior ischemic optic neuropathy (NAION), and hypersensitivity reactions. Obtain urgent medical help for chest pain, fainting, sudden loss of hearing or vision, or an erection lasting more than 4 hours. Routine laboratory monitoring is not generally required solely because tadalafil is being used for ED, but cardiovascular and other relevant medical risks should be assessed when clinically appropriate.

Pregnancy

Megalis 20 mg for erectile dysfunction is intended for use in adult men and is not indicated for use in women. Pregnancy guidance for tadalafil used for other indications should follow the relevant product-specific prescribing information.

Breastfeeding

Megalis 20 mg for erectile dysfunction is not indicated for use in women. Breastfeeding guidance for tadalafil used for another indication should be obtained from the relevant product-specific prescribing information.

Food, drink and interactions

Drinking substantial amounts of alcohol with tadalafil can increase the likelihood of dizziness, headache, increased heart rate, and low blood pressure. Excessive alcohol can also make erectile dysfunction worse. Limiting alcohol is advisable when tadalafil is used.

Food and drink

Tadalafil can be taken with or without food. Grapefruit or grapefruit juice may affect tadalafil metabolism and can increase exposure to the medicine, so avoiding grapefruit products is a cautious approach while taking tadalafil.

Storage

Store below 25°C. Keep the tablets protected from unsuitable heat or moisture and out of the reach of children.

Frequently asked questions

How long does tadalafil 20 mg last?

Tadalafil can support erectile function for up to 36 hours after a dose. This does not mean an erection lasts for 36 hours; an erection still depends on sexual stimulation.

Do I need to take Megalis 20 mg on an empty stomach?

No. Tadalafil can be taken with or without food, so a meal is not normally required to be timed around the tablet.

Can I take Megalis 20 mg every day?

The 20 mg strength is generally associated with as-needed tadalafil treatment rather than the usual once-daily ED regimen. Take it only according to the prescribed instructions and do not take more than one dose per day.

Does tadalafil cause an erection without sexual stimulation?

No. Tadalafil improves the erectile response to sexual stimulation; it does not automatically produce an erection or increase sexual desire.

What should I do if an erection lasts more than 4 hours?

Seek urgent medical attention. A prolonged erection (priapism) can damage penile tissue if it is not treated promptly.

Can I use Megalis 20 mg with nitroglycerin for chest pain?

No. Tadalafil and nitrates must not be used together because blood pressure can fall to a dangerously low level. Tell emergency medical staff when you last took tadalafil if you develop chest pain.

Can Cheap Generic Med ship Megalis 20 mg to the United States?

Cheap Generic Med serves the United States under its international shipping model. Delivery is typically estimated at 10–14 business days after dispatch, although customs or carrier delays can extend transit; prescription and personal-import requirements may also apply.

Will my Megalis order have tracking?

Under the standard Cheap Generic Med fulfilment model, tracked international shipping is used and a tracking number should be provided after dispatch. New tracking details may take 24–72 hours to show movement in the carrier system.

Sources

  1. greenbook.nafdac.gov.ng
  2. www.macleodspharma.com
  3. www.macleodspharma.com
  4. dailymed.nlm.nih.gov
  5. www.nhs.uk
  6. www.nda.or.ug

Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.

Additional information
Active IngredientsTadalafil
ManufacturerMacleods Pharmaceuticals, India
PackagingQty
strength20mg
Delivery Time6 To 15 days
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