Ikgdar 500 Mg/50 ml Injection

Dr. Emily Brown

Dr. Ryan Mitchell

SKU

CMS3153

USA Brand Name

Ikgdar

Strength

500mg/50ml

Generic Name

Rituximab

Manufacturer

Emcure Pharmaceuticals Ltd.

## Ikgdar 500 Mg/50 Ml Injection (Rituximab)

## What Is The Generic Name For Ikgdar 500 Mg/50 Ml Injection:

Rituximab is the generic version for Ikgdar 500 mg/50 ml Injection

## Which USA Brand is Equivalent To Ikgdar 500 Mg/50 Ml Injection (Rituximab):

Ikgdar

## About Ikgdar 500 Mg/50 Ml Injection (Rituximab)

Ikgdar 500 mg/50 ml Injection contains an active ingredient, Rituximab, which is used in the treatmentofnon-Hodgkin lymphoma (NHL),blood cancer (Chronic lymphocytic leukemia)&rheumatoid arthritis. Lymphoma is a type of cancer of a part of the immune system called the lymph system. There are many types of lymphoma, one is Hodgkin disease. The other are called non-Hodgkin lymphomas. Non-Hodgkin lymphomas start when a type of white blood cell, called a T cell or B cell, becomes abnormal. The cell divides, again & again, making more & more abnormal cells. These abnormal cells can spread to any other part of the body. Leukemia is cancer of the white blood cells that help your body fight infection. Blood cells form in bone marrow. In leukemia, the bone marrow produces nonstandard white blood cells. These cells crowd out the healthy blood cells, making it difficult for blood to do its work. In chronic lymphocytic leukemia (CLL), the lymphocytes outnumber the normal cells. Rheumatoid arthritis (RA) is a long-term autoimmune disorder which primarily affects the joints. It is a chronic disease that slowly worsens with time, causing inflammation in the joints & resulting in painful deformity & immobility. It especially affects small joints of the wrists, fingers, feet, and ankles. This medicine is available at all the leading pharmacy, drugstores, and medical supply stores & must be taken by doctor’s prescription only.

## Manufacturer :

Emcure Pharmaceuticals Ltd. is one of the leading pharmaceutical companies which manufacture Ikgdar 500 mg/50 ml Injection.It can be purchased from our online pharmacy.

## Strength :

Ikgdar 500 mg/50 ml Injection contains an active ingredient, Rituximab, which is available in other substitutes also at all the leading online pharmacy, drugstores, and medical supply stores.

## What Are The Uses Of The Ikgdar 500 Mg/50 Ml Injection (Rituximab):

Ikgdar 500 mg/50 ml Injection is used in the treatment in following conditions:

Non-Hodgkin’s Lymphoma

Chronic Lymphocytic Leukaemia

Rheumatoid Arthritis

Granulomatosis with polyangiitis and microscopic polyangiitis

## How Ikgdar 500 Mg/50 Ml Injection (Rituximab) Works:

Ikgdar 500 mg/50 ml Injection has an active ingredient; Rituximab is a monoclonal antibody that specifically binds to receptors on cancer cells. It marks the cancer cells for demolition by the body’s immune system. Rituximab is a monoclonal antibody which targets the CD20 antigen, which is expressed on the surface of pre-B & mature B-lymphocytes. After binding to CD20, rituximab mediates B-cell breakdown. The mechanism of cell lysis includes complement dependent cytotoxicity (CDC) & antibody dependent cell-mediated cytotoxicity (ADCC).

## Before You Use Ikgdar 500 Mg/50 Ml Injection (Rituximab):

Make sure that:

You are not allergic to Rituximab

You are not having any serious Disease

Your doctor must be learned about your health history like your pre- existing disease, surgeries & Medications, Supplements, Food Habits, lifestyle, etc.

## What Should You Avoid While Taking Ikgdar 500 Mg/50 Ml Injection (Rituximab):

You should avoid taking alcohol

You should avoid driving

You should avoid taking live vaccination

You should avoid taking Medicines without prescriptions

## When Not To Use Ikgdar 500 Mg/50 Ml Injection (Rituximab):

You should not take Ikgdar 500 mg/50 ml Injection if you:

Have ever noticed any Allergy/Hypersensitivity

Have liver problems

Have active infections

Have autoimmune disorders

Have cardiac dysfunction

Have Hepatitis B

Have Tumor Lysis Syndrome

Have bone marrow suppression

Have severe immunocompromise

Have Kidney disease

Are Pregnant/Conceiving/Breastfeeding

## Tell Your Doctor If You:

Have Allergy to the Injection

Are taking Alcohol or Other Drugs

Have Liver/ Kidney disease

Have high blood pressure ,

Have infections

Have systemic lupus erythematosus

Have heart problems

Have lung disease or breathing problems

Are Pregnant or Trying to Conceive

Are Breastfeeding

## Dosage :

Ikgdar 500 mg/50 ml Injection contains an active ingredient, Rituximab, which is used in the treatment ofnon-Hodgkin lymphoma (NHL),blood cancer (Chronic lymphocytic leukemia)andrheumatoid arthritis. This medicine is accessible in different strengths & substitutes & must be purchased or given on doctor’s prescription only. You must consult your physician for dosage and time because age and severity of the disease differ from person to person and it can only be judged by your doctor.

Adults are advised to take Ikgdar 500 mg/50 ml Injection at a fixed time with or without food as instructed by your Doctor. You must take Ikgdar 500 mg/50 ml Injection regularly on time for better results.

## How Much Of The Ikgdar 500 Mg/50 Ml Injection (Rituximab) to Be Used:

As Ikgdar 500 mg/50 ml Injection is available in various strengths and substitutes, Patients are always advised to follow their doctor’s prescriptions and instructions to take Ikgdar 500 mg/50 ml Injection. Do not take the Injection on your own & for longer period than recommended by doctor.

## How To Take The Ikgdar 500 Mg/50 Ml Injection (Rituximab):

Ikgdar 500 mg/50 ml Injection should be taken at a fixed time as directed by your doctor. Your doctor or nurse will give you Ikgdar 500 mg/50 ml Injection. Kindly do not self administer this medicine.

## For How Long Should You Continue Using Ikgdar 500 Mg/50 Ml Injection (Rituximab):

You are always advised to take Ikgdar 500 mg/50 ml Injection as prescribed. Do not start/stop using this medicine yourself. Follow all the instructions given by your doctor. Do not take the Injection in larger or smaller quantity or for longer period than suggested by your doctor.

## Overdose :

Seek medical emergency treatment and/ or contact your surgeon immediately in case of any overdose symptoms. Since Ikgdar 500 mg/50 ml Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency measure will be initiated immediately by your physician if they observe overdose symptoms.

## Missed Dose:

The missed dosage of the injection should be administered by the doctor as soon as possible. It is strictly suggested to skip the missed dosage if it is already time for your next scheduled dosage. You must not double the dosage of the prescription to make up for the missed dosage. Since Ikgdar 500 mg/50 ml Injection is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dosage is very low.

## What Are The Side Effects Of The Ikgdar 500 Mg/50 Ml Injection (Rituximab):

Low blood pressure

Nausea and Vomiting

Chills and fever

Abdominal pain

Decrease in white blood cells and platelets

Itching

Infections

Headache

Muscle aches and pain

Cough

Weakness

Edema (swelling)

Hair loss

Febrile neutropenia

## What Are The Common Drug Interactions:

Few medicines have been reported to interact with Ikgdar Injection . This interaction may produce some unnecessary or adverse effects and/or cause your drug not to work properly. You must always discuss with your doctor if you are taking other prescription/ Supplements so that well planned medication can be given. It interacts with the following medicines:

Live attenuated vaccines and related products

Adalimumab

Topotecan

It can also interact with following disease condition:

Autoimmune disorders

Cardiac Dysfunction

Hepatitis B

Tumor Lysis Syndrome

Bone marrow suppression

Renal impairment

## Warning And Precaution:

Ikgdar 500 mg/50 ml Injection can worsen the conditions like:

Allergy

Liver/kidney disease

You must use an effective method of contraception before starting treatment, during treatment, & until 12 months after stopping treatment

Regular monitoring of complete blood cell counts is necessary during treatment with this medicine

Regularly monitor your blood pressure level while taking this medicine

You should not drive or operate heavy machinery while taking this medicine as it may cause nausea and vomiting

Always consult with your doctor immediately to get best possible treatment if you are suffering from any of the above mentioned conditions.

## Things To Remember:

Keep the Ikgdar 500 mg/50 ml Injection out of reach and sight of the children

This medicine is strictly not used to treat children, adolescents, and elderly

Ikgdar 500 mg/50 ml Injection is not recommended for use in pregnant women due to the increased risk of harmful effects on the unborn baby

You must always examine the information precisely written on the leaflet/ insert of the medicine

Always consult your medical doctor if you have any doubt in case of the dosage, time & strength of the medicine.

## Indications :

Ikgdar 500 mg/50 ml Injection should be taken for cancer treatment. Do not take this medication for longer period than suggested by the Doctor.

## Stora ge :

Store the Ikgdar 500 mg/50 ml Injection at room temperature in dark and dry place. Make sure the Injection is intact and not damaged while purchasing or storing.