Epofer 10000 IU/ml Injection

Dr. Emily Brown

Dr. Ryan Mitchell

SKU

CMS3215

USA Brand Name

Epogen

Strength

10000IU

Generic Name

Erythropoietin

Manufacturer

Emcure Pharmaceuticals

## Epofer 10000 IU/Ml Injection (Erythropoietin)

## What Is The Generic Name For Epofer 10000 IU/Ml Injection:

Erythropoietin is the generic version for Epofer 10000 iu/ml Injection

## Which USA Brand is Equivalent To Epofer 10000 IU/Ml Injection (Erythropoietin):

Epogen

## About Epofer 10000 IU/Ml Injection (Erythropoietin)

Epofer 10000 iu/ml Injection contains an active ingredient, Erythropoietin, which is used in the treatment of anemia due to chronic kidney disease and anemia due to chemotherapy. Anemia refers to condition where there is a decreased level of red blood cells (RBCs). Patients of chronic kidney disease (CKD) slowly develop anemia, which get worsens as the disease progresses. As the kidneys partially but permanently lose their functions in CKD, there is not enough formation of erythropoietin. This hormone promotes RBCs formation by the bone marrow. As a result, formation of RBCs is affected, leading to fewer RBCs than normal. Certain types of cancer which affect blood & bone marrow, such as, multiple myeloma, leukemia, & lymphoma, can crowd out red blood cells. Also, cancer treatment, including chemotherapy & radiotherapy, leads to anemia in cancer patients. This happens when some drugs or radiation kill the red blood cells along with the targeted cancerous cells. This medicine is available at all the leading pharmacy, drugstores, & medical supply stores & must be taken strictly by doctor’s prescription only.

## Manufacturer :

Emcure Pharmaceuticals Ltd. is one of the leading pharmaceutical companies which manufacture Epofer 10000 iu/ml Injection.

## Strength :

Epofer 10000 iu/ml Injection contains an active constituent, Erythropoietin. It is obtainable in other substitutes also at all the leading online pharmacy, drugstores, and medical supply stores.

## What Are The Uses Of The Epofer 10000 IU/Ml Injection (Erythropoietin):

Epofer 10000 iu/ml Injection is used in the treatment in following conditions:

Chronic kidney disease associated anemia

Chemotherapy associated anemia

Anemia due to use of medicines

Anemia associated with surgery

## How Epofer 10000 IU/Ml Injection (Erythropoietin) Works:

Epofer 10000 iu/ml Injection has an active ingredient; Erythropoietin is an erythropoiesis-stimulating agent (ESA) which works by stimulating the bone marrow (soft tissue inside the bones that produces red blood cells) to produce more red blood cells. Erythropoietin shows its effects by binding to the erythropoietin receptor (EpoR). Erythropoietin binds to the erythropoietin receptor on the red cell progenitor surface & activates a JAK2 signalling cascade. This initiates the STAT5, PIK3 & Ras MAPK pathways which results in differentiation, survival & proliferation of the erythroid cell.

## Before You Use Epofer 10000 IU/Ml Injection (Erythropoietin):

Make sure that:

You are not allergic to Erythropoietin

You are not having any serious Disease

Your doctor must be learned about your medicinal history like your pre- existing disease, surgeries & Medications, Supplements, Food Habits, lifestyle, etc.

## What Should You Avoid While Taking Epofer 10000 IU/Ml Injection (Erythropoietin):

You should avoid taking alcohol

You should avoid driving

You should avoid taking Medicines without prescriptions

## When Not To Use Epofer 10000 IU/Ml Injection (Erythropoietin):

You should not take Epofer 10000 iu/ml Injection if you:

Have ever noticed any Allergy/Hypersensitivity

Have liver problems

Have kidney problems

Are pregnant

Have infections

Are cancer patient with Non-chemotherapy associated anemia

Have high blood pressure

Have history of pure red cell aplasia

Have electrolyte disturbance

Are breastfeeding

## Tell Your Doctor If You:

Have Allergy to the Injection

Are taking Alcohol or Other Drugs

Have ongoing cancer treatment

Have surgery of heart or blood vessels

Have heart or blood vessels disorder

Have seizures

Have Liver disease

Have kidney disorder

Have infections

## Dosage :

Epofer 10000 iu/ml Injection contains an active ingredient, Erythropoietin, which is used in the treatment of anemia due to chronic kidney disease and anemia due to chemotherapy. This medicine is available in different substitutes & strengths & has got to be purchased or given on doctor’s prescription only. You must consult your physician for adjustment of dosage & time of the medicine because age and severity of the disease differ from person to person and it can only be best judged by your doctor.

Adults are advised to take Epofer 10000 iu/ml Injection at a fixed time with or without food as instructed by your Doctor. You must take Epofer 10000 iu/ml Injection regularly on time for better results.

## How Much Of The Epofer 10000 IU/Ml Injection (Erythropoietin) to Be Used:

As Epofer 10000 iu/ml Injection is available in various strengths and substitutes, Patients are always advised to follow their doctor’s prescriptions and instructions to take Epofer 10000 iu/ml Injection. You must not take the Injection on your own & for longer period than recommended by doctor.

## How To Take The Epofer 10000 IU/Ml Injection (Erythropoietin):

Epofer 10000 iu/ml Injection should be taken at a fixed time as directed by your doctor. Your doctor or nurse will give you Epofer 10000 iu/ml Injection. Kindly do not self administer this medicine.

## For How Long Should You Continue Using Epofer 10000 IU/Ml Injection (Erythropoietin):

You are always advised to take Epofer 10000 iu/ml Injection as prescribed. Do not start/stop using this medicine yourself. You must strictly follow all the directions given by your doctor. You must not take the Injection in larger or smaller quantity or for longer period than suggested by your doctor.

## Overdose :

You must seek out medical emergency treatment and/ or contact your surgeon without delay in case of any overdose symptoms. Since Epofer 10000 iu/ml Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency measure will be initiated without delay by your physician if they observe overdose symptoms.

## Missed Dose:

The missed dosage of the injection should be administered by the medical doctor as soon as possible. It is strictly recommended to skip the missed dosage if it is already time for your next planned dosage. You must not double the dosage of the treatment to make up for the missed dosage. Since Epofer 10000 iu/ml Injection is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dosage is very low.

## What Are The Side Effects Of The Epofer 10000 IU/Ml Injection (Erythropoietin):

Fever

Nausea

Vomiting

Mouth sores

Headache

Muscle or joint pain

Cough

Diarrhea

Swelling and redness at the injection site

Stomach discomfort and pain

Severe skin allergy

Edema

Difficulty in breathing

Wheezing

Dizziness and fainting

Upper respiratory tract infection

Difficulty in swallowing

Increased blood pressure

Pure red cell aplasia

## What Are The Common Drug Interactions:

Few medicines have been reported to interact with Epofer 10000 iu/ml Injection. These interactions may generate some needless or adverse effects and/or cause your drug not to work properly. You must always have a conversation with your doctor if you are taking other prescription/ Supplements so that well planned medication can be given. It interacts with the following medicines:

Telmisartan

Ramipril

Losartan

Olmesartan Medoxomil

Cyclosporine

Thalidomide

It can also interact with following disease condition:

Infections

Hypertension

Seizure disorders

Blood clotting disorders

Hemodialysis

## Warning And Precaution:

Epofer 10000 iu/ml Injection can worsen the conditions like:

Allergy

Kidney/ Liver disease

Epofer 10000 iu/ml Injection is not recommended for use in children under 18 years of age

You must use a reliable contraceptive method to prevent pregnancy while you are on this medication

You must regularly get your blood tests done to monitor your blood cells, liver and kidney function, and electrolyte levels during treatment with this medicine

You must regularly check your blood pressure while taking this medicine

You must not take this medicine if you are pregnant, planning to conceive or breastfeeding

You must not drive or operate heavy machinery at the same time as taking this medicine as it may cause dizziness

Always consult with your medical doctor straight away to get best possible treatment if you are observing any of the above mentioned conditions.

## Things To Remember:

Keep the Epofer 10000 iu/ml Injection out of reach and sight of the children

This medicine is strictly used with caution for treatment of children and elderly

Epofer 10000 iu/ml Injection is not recommended for use in pregnant women due to the increased risk of harmful effects on the unborn baby

You must always check up the information in particular written on the leaflet/ insert of the medicine

Always consult with your medical doctor if you have any uncertainty in case of the dosage, time & strength of the medicine.

## Indications :

Epofer 10000 iu/ml Injection should be taken for cancer treatment. Do not take this prescription for longer period than suggested by the medical doctor.

## Storage :

Store the Epofer 10000 iu/ml Injection at room temperature in dark and dry place. Make sure the Injection is intact & not damaged while purchasing or storing.