Endoxan 1000 mg/ 20ml Injection

Dr. Emily Brown

Dr. Ryan Mitchell

SKU

CMS2979

USA Brand Name

Endoxan

Strength

1000mg

Generic Name

Cyclophosphamide

Manufacturer

Zydus Cadila

## Endoxan 1000 Mg/20 Ml Injection (Cyclophosphamide)

## What Is The Generic Name For Endoxan 1000 Mg/20 Ml Injection:

Cyclophosphamide is the generic version for Endoxan 1000 mg/20 ml Injection

## Which USA Brand is Equivalent To Endoxan 1000 Mg/20 Ml Injection (Cyclophosphamide):

Endoxan

## About Endoxan 1000 Mg/20 Ml Injection (Cyclophosphamide)

Endoxan 1000 mg/20 ml Injection contains an active ingredient, Cyclophosphamide, which is used in the treatment of cancer and nephrotic syndrome. Cancer starts in the cells, which are the building blocks of the body. Generally, body forms new cells as it need them, replacing the old cells that die. Sometimes this process goes wrong and new cells grow even when the body does not need them, & old cells do not die when they should. These extra cells form a mass called a tumor which can be benign or malignant. Nephrotic syndrome is a kidney disorder which is characterized by too much protein in the urine, low albumin levels in the blood & swelling in legs, feet and ankles. It can be caused due to disease of the kidney like minimal-change nephropathy, focal segmental glomerulosclerosis, etc. or due to diseases affecting the body like lupus, diabetes, etc. This medicine is available at all the leading pharmacy, drugstores, and medical supply stores & must be taken by doctor’s prescription only.

## Manufacturer :

Zydus Cadila Ltd. is one of the leading pharmaceutical companies which manufacture Endoxan 1000 mg/20 ml Injection. It can be purchased from our online pharmacy.

## Strength :

Endoxan 1000 mg/20 ml Injection contains an active ingredient, Cyclophosphamide, which is available in other substitutes also at all the leading online pharmacy, drugstores, and medical supply stores.

## What Are The Uses Of The Endoxan 1000 Mg/20 Ml Injection (Cyclophosphamide):

Endoxan 1000 mg/20 ml Injection is used in the treatment in following conditions:

Malignant Disease

Ovarian Cancer

Breast cancer

Nephrotic Syndrome

## How Endoxan 1000 Mg/20 Ml Injection (Cyclophosphamide) Works:

Endoxan 1000 mg/20 ml Injection has an active ingredient; Cyclophosphamide is an antineoplastic in the class of alkylating agents. They prevent tumor growth by cross-linking guanine bases in DNA double-helix strands – directly attacking DNA. This makes the strands unable to uncoil & separate. As this is essential in DNA replication, the cells can no longer divide. Additionally, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing & causes a miscoding of DNA.

## Before You Use Endoxan 1000 Mg/20 Ml Injection (Cyclophosphamide):

Make sure that:

You are not allergic to Cyclophosphamide

You are not having any serious Disease

Your doctor must be learned about your medicinal history like your pre- existing disease, surgeries & Medications, Supplements, Food Habits, lifestyle, etc.

## What Should You Avoid While Taking Endoxan 1000 Mg/20 Ml Injection (Cyclophosphamide):

You should avoid taking alcohol

You should avoid driving

You should avoid taking Medicines without prescriptions

## When Not To Use Endoxan 1000 Mg/20 Ml Injection (Cyclophosphamide):

You should not take Endoxan 1000 mg/20 ml Injection if you:

Have ever noticed any Allergy/Hypersensitivity

Have liver problems

Have active infections

Have bleeding problems

Have Kidney disease

Are Pregnant/Conceiving/Breastfeeding

## Tell Your Doctor If You:

Have Allergy to the Injection

Are taking Alcohol or Other Drugs

Have Liver/ Kidney disease

Have blood disorder

Have infections

Have urinary outflow obstruction

Have bone marrow suppression

Have heart disorder

Are Pregnant or Trying to Conceive

Are Breastfeeding

## Dosage :

Endoxan 1000 mg/20 ml Injection contains an active ingredient, Cyclophosphamide, which is used in the treatment of cancer and nephrotic syndrome. This medicine is accessible in different substitutes & strengths & must be purchased or given on doctor’s prescription only. You must consult your physician for dosage and time because age and severity of the disease differ from person to person and it can only be judged by your doctor.

Adults are advised to take Endoxan 1000 mg/20 ml Injection at a fixed time with or without food as instructed by your Doctor. You must take Endoxan 1000 mg/20 ml Injection regularly on time for better results.

## How Much Of The Endoxan 1000 Mg/20 Ml Injection (Cyclophosphamide) to Be Used:

As Endoxan 1000 mg/20 ml Injection is available in various strengths and substitutes, Patients are always advised to follow their doctor’s prescriptions and instructions to take Endoxan 1000 mg/20 ml Injection. Do not take the Injection on your own & for longer period than recommended by doctor.

## How To Take The Endoxan 1000 Mg/20 Ml Injection (Cyclophosphamide):

Endoxan 1000 mg/20 ml Injection should be taken at a fixed time as directed by your doctor. Your doctor or nurse will give you Endoxan 1000 mg/20 ml Injection. Kindly do not self administer this medicine.

## For How Long Should You Continue Using Endoxan 1000 Mg/20 Ml Injection (Cyclophosphamide):

You are always advised to take Endoxan 1000 mg/20 ml Injection as prescribed. Do not start/stop using this medicine yourself. Follow all the instructions given by your doctor. Do not take the Injection in larger or smaller quantity or for longer period than suggested by your doctor.

## Overdose :

Seek medical emergency treatment and/ or contact your surgeon immediately in case of any overdose symptoms. Since Endoxan 1000 mg/20 ml Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the probability of an overdose is much lower. However, emergency measure will be initiated immediately by your physician if they observe overdose symptoms.

## Missed Dose:

The missed dosage of the injection should be administered by the doctor as soon as possible. It is strictly suggested to skip the missed dosage if it is already time for your next scheduled dosage. You must not double the dosage of the prescription to make up for the missed dosage. Since Endoxan 1000 mg/20 ml Injection is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dosage is very low.

## What Are The Side Effects Of The Endoxan 1000 Mg/20 Ml Injection (Cyclophosphamide):

Infections

Decrease in blood cell count

Hair loss

Fever

Weakness

Loss of appetite

Nausea and Vomiting

Diarrhea

Headache

Increased sweating

Skin rash

Blood in urine

## What Are The Common Drug Interactions:

Few medicines have been reported to interact with Endoxan 1000 mg/20 ml Injection. This interaction may produce some needless or adverse effects and/or cause your drug not to work properly. You must always talk about with your doctor if you are taking other prescription/ Supplements so that well planned medication can be given. It interacts with the following medicines:

Clozapine

Diltiazem

Warfarin

Live attenuated vaccines and related products

Itraconazole

Fluconazole

Inactivated influenza vaccine

It can also interact with following disease condition:

Infections

Liver disease

Renal impairment

## Warning And Precaution:

Endoxan 1000 mg/20 ml Injection can worsen the conditions like:

Allergy

Liver/kidney disease

Regular monitoring of complete blood cell counts and kidney function is necessary during treatment with this medicine

You must not drive or operate heavy machinery while taking this medicine as it may cause nausea and vomiting

You must drink plenty of fluids to prevent urinary problems while taking this medication

Always consult with your doctor straight away to get best possible treatment if you are observing any of the above mentioned conditions.

## Things To Remember:

Keep the Endoxan 1000 mg/20 ml Injection out of reach and sight of the children

This medicine is strictly used to treat with caution in children, adolescents, and elderly

Endoxan 1000 mg/20 ml Injection is not recommended for use in pregnant women due to the increased risk of harmful effects on the unborn baby

You must always check up the information precisely written on the leaflet/ insert of the medicine

Always consult your medical doctor if you have any uncertainty in case of the dosage, time & strength of the medicine.

## Indications :

Endoxan 1000 mg/20 ml Injection should be taken for cancer treatment. Do not take this prescription for longer period than suggested by the Doctor.

## Storage :

Store the Endoxan 1000 mg/20 ml Injection at room temperature in dark and dry place. Make sure the Injection is intact and not damaged while purchasing or storing.