Duoflo Combipack

Dr. Emily Brown

Dr. Ryan Mitchell

SKU

CMS4232

USA Brand Name

Vesicare

Strength

400mcg + 5mg

Generic Name

Tamsulosin (400mcg) + Solifenacin (5Mg)

Manufacturer

Cipla Ltd

## Duoflo Combipack (Solifenacin & Tamsulosin)

## What Is The Generic Name For Duoflo Combipack:

Solifenacin & Tamsulosin is the generic version for Duoflo Combipack

## Which USA Brand is Equivalent To Duoflo Combipack (Solifenacin & Tamsulosin):

Vesicare

## About Duoflo Combipack (Solifenacin & Tamsulosin)

Duoflo Combipack contains two active ingredients. Solifenacin & Tamsulosin is used for the treatment of an overactive bladder. A condition which is characterized by symptoms such as a frequent feeling of a need to urinate, inability to control urination, sudden urge to urinate, leaking of urine, etc. This medicine is also used for the treatment of benign prostatic hyperplasia. Overactive bladder syndrome is a situation in which the bladder squeezes urine out at the wrong time. Common causes of this disease are Nerve problems, too much fluid, and too much caffeine. Benign prostatic hyperplasia (BPH) is the condition in which there is an overgrowth of the prostate gland, a gland located between the penis & the bladder. The prostate gland surrounds the urethra & produces a fluid that forms a part of the semen. This medicine is readily obtainable at all the primary pharmacy, drugstores, & medical supply stores & it must be taken strictly on doctor’s prescription only.

## Manufacturer :

Cipla Ltd. is one of the first pharmaceutical companies which manufacture Duoflo Combipack.

## Strength :

Duoflo Combipack contains two active constituents, Solifenacin (5 mg) & Tamsulosin (400 mcg). This medicine is readily obtainable in other substitutes and also at all the primary online pharmacy, drugstores, & medical supply stores.

## What Are The Uses Of The Duoflo Combipack (Solifenacin & Tamsulosin):

Duoflo Combipack is used in the treatment in the following conditions:

Overactive bladder (OAB) symptoms

Benign prostatic hyperplasia

## How Duoflo Combipack (Solifenacin & Tamsulosin) Works:

Duoflo Combipack has two active ingredients; Solifenacin & Tamsulosin. Tamsulosin is an alpha-blocker, and Solifenacin is an antimuscarinic. They act by relaxing muscles of the urinary bladder exit & prostate gland to prevent frequent, urgent, or uncontrolled urination. Solifenacin is a cholinergic receptor antagonist which is selective for the M3 receptor subtype. The binding of acetylcholine to these receptors, mainly M3, plays a significant role in the contraction of smooth muscle. Solifenacin by preventing the binding of acetylcholine. These receptors reduce soft muscle tone in the bladder that allows the bladder to retain larger volumes of urine and reduce the number of micturition, urgency & incontinence episodes.

## Before You Use Duoflo Combipack (Solifenacin & Tamsulosin):

Make certain that:

You are not sensitive to Solifenacin & Tamsulosin

You are not having some grave Disease

Your doctor must be well informed concerning your medicinal history like your pre-existing disease, surgeries & Medications, Food Habits, Supplements, lifestyle, etc.

## What Should You Avoid While Taking Duoflo Combipack (Solifenacin & Tamsulosin):

You should avoid taking alcohol

You should avoid driving

You should avoid taking Medicines without prescriptions

## When Not To Use Duoflo Combipack (Solifenacin & Tamsulosin):

You should not take Duoflo Combipack if you:

Have ever noticed any Allergy/Hypersensitivity

Have liver problems

Have kidney problems

Are pregnant

Have urinary retention

Have narrow-angle glaucoma

Have gastric retention

Have infections

Are breastfeeding

## Tell Your Doctor If You:

Have an Allergy to the Tablet

Are taking Alcohol or Other Drugs

Have Liver/ Kidney disease

Have to undergo eye surgery

Have angioedema

Have CNS side effects

Have infections

## Dosage :

Duoflo Combipack contains two active ingredients. Solifenacin & Tamsulosin is used for the treatment of an overactive bladder & benign prostatic hyperplasia. This medicine is readily obtainable in different substitutes & strength. It has got to be purchased or taken on a doctor’s prescription only. You must speak about with your medical doctor for adjustment of dosage & time of the medicine given the fact that age & severity of the disease vary from person to person. It can only be judged most excellent by your doctor.

Adults are advised to take Duoflo Combipack at a fixed time with food as instructed by your Doctor. You must take Duoflo Combipack regularly on time for better results.

## How Much Of The Duoflo Combipack (Solifenacin & Tamsulosin) to Be Used:

As Duoflo Combipack is available in various strengths & substitutes, Patients are always advised to follow their doctor’s prescriptions & instructions to take Duoflo Combipack. You should not take the Tablet on your own & for a longer time than recommended by the doctor.

## How To Take The Duoflo Combipack (Solifenacin & Tamsulosin):

Take Duoflo Combipack in the dose and duration as suggested by your doctor. Swallow the medicine as a whole & not chew, crush, or break the Tablet. Duoflo Combipack can be taken with food, but it is better to take it at a fixed time.

## For How Long Should You Continue Using Duoflo Combipack (Solifenacin & Tamsulosin):

You are always advised to take Duoflo Combipack as prescribed. You should not start/stop using this medication abruptly on your own. You must follow all the guidelines given by your doctor, rigorously. You should not take the Tablet in a larger or smaller degree or for an extended period than recommended by your doctor.

## Overdose :

You should seek medical emergency treatment and get in touch with your medical doctor instantaneously in case of some overdose symptoms. The emergency action will be initiated without delay by your medical doctor if they detect overdose symptoms.

## Missed Dose:

The missed dosage of the Tablet has to be administered as fast as possible. You must strictly skip the missed dosage if it is by now the time for your next planned dosage. It is strictly recommended not to double the dosage of the treatment to make up for the missed dosage.

## What Are The Side Effects Of The Duoflo Combipack (Solifenacin & Tamsulosin):

Dry mouth

Constipation

Nausea and vomiting

Abdominal pain

Cough

Nasal dryness

Blurred vision

Dry skin

Headache

Dizziness

Extreme tiredness

Ejaculation disorder

Back pain

Stomach upset

Dyspepsia

## What Are The Common Drug Interactions:

Several medicines have been reported to interact with Duoflo Combipack. These interactions might produce some unwanted or unfavorable effects or may cause your drug not to function correctly. You must continuously discuss with your doctor if you are taking other prescription/ Supplements so that well-intended medication can be given. It interacts with the following medicines:

Rifampicin

Carbamazepine

Phenobarbitone

Cilnidipine

Benidipine

Amlodipine

Phenytoin

S-Amlodipine

Clotrimazole

Itraconazole

Clozapine

Amiodarone

Fluoroquinolones

It can also interact with the following disease condition:

Liver disease

Infections

Kidney disease

Central nervous system disorder

QT Prolongation

## Warning And Precaution:

Duoflo Combipack can worsen the terms like:

Infections

Kidney/ Liver disease

Allergy

Children do not recommend the use of this medicine under 18 years of age

You have to get your blood tests done regularly. to check your blood cells, electrolyte levels & hemoglobin levels, liver & kidney function, during treatment with this medicine

You should also get your blood pressure & levels of proteins in urine frequently checked while taking this medicine

Use of this medicine may cause dry mouth, so must try chewing on sugar-free gum or taking small sips of water

You must avoid caffeine, alcohol, or carbonated drinks as they can worsen the symptoms.

You should not drive or operate heavy machines concurrently as taking this medicine as it may cause dizziness

You are supposed not to take this medicine if you are pregnant, planning to conceive or breastfeeding

You must always talk about with your medical doctor to get the most excellent possible treatment if you are observing several of the conditions as mentioned above.

## Things To Remember:

Keep the Duoflo Combipack out of reach & sight of the children

This medicine is strictly used with vigilance for treatment of children

Duoflo Combipack is not suggested for use in pregnant women due to the increased risk of harmful effects on the unborn baby

You should always check up the information in particular printed on the leaflet/ insert of the medicine

You must always talk about with your medical doctor if you have any doubt in case of the dosage, time & strength of the drug.

## Indications :

Duoflo Combipack should be taken as recommended by your doctor. Do not take this prescription for a more extended period than prescribed by the medical doctor.

## Storage :

Store the Duoflo Combipack at room temperature in dark & dry place. Make sure the Tablet is intact & not broken while purchasing or storing.