Crizalk 250 Mg Capsule

Dr. Emily Brown

Dr. Ryan Mitchell

SKU

CMS3023

USA Brand Name

Crizalk

Strength

250mg

Generic Name

Crizotinib

Manufacturer

Pfizer Pharmaceuticals

## Crizalk 250 Mg Capsule (Crizotinib)

## What Is The Generic Name For Crizalk 250 Mg Capsule:

Crizotinib is the generic version for Crizalk 250 mg Capsule

## Which USA Brand is Equivalent To Crizalk 250 Mg Capsule (Crizotinib):

Crizalk

## About Crizalk 250 Mg Capsule (Crizotinib)

Crizalk 250 mg Capsule contains an active ingredient, Crizotinib, which is beneficial in the curing symptoms of non-small cell lung cancer. This medicine is used in patients in which it has spread to other parts of the body, & who have not had previous treatment for cancer. Crizotinib can be used only if your cancer has a specific genetic marker (an abnormal “ALK” gene). Non-small-cell lung cancer (NSCLC) is epithelial lung cancer excluding small cell lung carcinoma (SCLC). NSCLCs are comparatively insensitive to chemotherapy, compared to small cell carcinoma. This medicine is available at all the leading pharmacy, drugstores, and medical supply stores & must be taken by doctor’s prescription only.

## Manufacturer :

Pfizer Pharmaceuticals is one of the leading pharmaceutical companies which manufacture Crizalk 250 mg Capsule. It can be purchased from our online pharmacy.

## Strength :

Crizalk 250 mg Capsule contains an active ingredient, Crizotinib, which is available in other substitutes also at all the leading online pharmacy, drugstores, and medical supply stores.

## What Are The Uses Of The Crizalk 250 Mg Capsule (Crizotinib):

Crizalk 250 mg Capsule is used in the treatment in following conditions:

Non-Small Cell Lung Cancer

## How Crizalk 250 Mg Capsule (Crizotinib) Works:

Crizalk 250 mg Capsule has an active ingredient; Crizotinib which is a tyrosine kinase receptor inhibitor. It inhibits anaplastic lymphoma kinase (ALK), hepatocyte growth factor receptor (HGFR, c-MET), & Recepteur d’Origine Nantais (RON). Abnormality in the ALK gene caused by mutations or translocations may lead to expression of oncogenic fusion proteins. In patients having NSCLC, they have the EML4-ALK gene. Crizotinib inhibits ALK tyrosine kinase which ultimately results in decreased proliferation of cells which carry the genetic mutation & tumor survivability.

## Before You Use Crizalk 250 Mg Capsule (Crizotinib):

Make sure that:

You are not allergic to Crizotinib

You are not having any serious Disease

Your doctor must be learned about your health history like your pre- existing disease, surgeries & Medications, Supplements, Food Habits, lifestyle, etc.

## What Should You Avoid While Taking Crizalk 250 Mg Capsule (Crizotinib):

You should avoid taking alcohol

You should avoid driving

You should avoid taking Medicines without prescriptions

## When Not To Use Crizalk 250 Mg Capsule (Crizotinib):

You should not take Crizalk 250 mg Capsule if you:

Have ever noticed any Allergy/Hypersensitivity

Have you have liver problems

Have heart disorder

Have gastrointestinal disorder

Have eye disorder

Have lung disorder

Have infections

Have Kidney disease

Are Pregnant/Conceiving/Breastfeeding

## Tell Your Doctor If You:

Have Allergy to the Capsule

Are taking Alcohol or Other Drugs

Have Liver/ Kidney disease

Have lung disorder

Have heart disorder

Are Pregnant or Trying to Conceive

Are Breastfeeding

## Dosage :

Crizalk 250 mg Capsule contains an active ingredient, Crizotinib, which is beneficial in the curing symptoms of non-small cell lung cancer. This medicine is accessible in different strengths & substitutes & must be purchased or given on doctor’s prescription only. You should consult your doctor for dosage and time because age and severity of the disease differ from person to person and it can only be judged by your doctor.

Adults are advised to take Crizalk 250 mg Capsule at a fixed time with or without food as instructed by your Doctor. You must take Crizalk 250 mg Capsule regularly on time for better results.

## How Much Of The Crizalk 250 Mg Capsule (Crizotinib) to Be Used:

As Crizalk 250 mg Capsule is available in various strengths and substitutes, Patients are always advised to follow their doctor’s prescriptions and instructions to take Crizalk 250 mg Capsule. Do not take the Capsule on your own & for longer time than recommended by doctor.

## How To Take The Crizalk 250 Mg Capsule (Crizotinib):

Take Crizalk 250 mg Capsule in the dose and duration as advised by your doctor. Swallow the whole capsule. Don’t try to chew, crush or break the Capsule. Crizalk 250 mg Capsule is to be taken with food, but it is better to take it at a fixed time.

## For How Long Should You Continue Using Crizalk 250 Mg Capsule (Crizotinib):

You are always advised to take Crizalk 250 mg Capsule as prescribed. Do not start/stop using this medicine yourself. Strictly abide by the instructions given by your doctor Do not take the Capsule in larger or smaller amount or for longer period than suggested by your doctor.

## Overdose:

Patient must seek for emergency medical attention and/or contact doctor immediately in case of any overdose symptoms. Symptoms like dizziness, tremor, confusion & sweating after taking the dose should be reported immediately. Emergency remedial treatment will be initiated by your doctor if they are suspecting overdose symptoms.

## Missed Dose:

The missed dosage of the drug must be taken by you as soon as possible. It is suitable to skip the missed dosage of the drug if it is already time for your next scheduled dosage. You must not take double dosage of this medicine to make up for the missed dosage.

## What Are The Side Effects Of The Crizalk 250 Mg Capsule (Crizotinib):

Black or tarry stools

Body aches or Pain

Cough

Chest pain or discomfort

Fever or chills

Headache

Rapid weight gain

Difficulty or painful urination

Blood in urine and stools

Pale skin

Change in taste

Decreased appetite

Nausea

Vomiting

Edema (swelling)

Diarrhea

Constipation

Abdominal pain

Vision disorder

Dizziness

Fatigue

Rash

Decreased white blood cell count (neutrophils)

## What Are The Common Drug Interactions:

Few medicines have been reported to interact with Crizalk 250 mg Capsule. This interaction may produce some unnecessary or adverse effects and/or cause your drug not to work properly. You must always discuss with your doctor if you are taking other prescription/ Supplements so that well administrated medication can be provided. It interacts with the following medicines:

Escitalopram

Atazanavir

Amoxapine

Ofloxacin

Fluconazole

Cisapride

It can also interact with following disease condition:

Heart rhythm disorders

Gastro-intestinal disease

Liver Disease

Kidney Disease

Lung Toxicity

## Warning And Precaution:

Crizalk 250 mg Capsule can worsen the conditions like:

Allergy

Liver/kidney disease

You must use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it

You must drink plenty of fluids and inform your doctor if diarrhea doesn’t stop or if you find blood in your stools

You must have regular blood tests done to monitor your liver function while you are having treatment with this medicine

You must monitor your blood pressure regularly while taking this medication

You should not drive or operate heavy machinery while taking this medicine as it may cause nausea and vomiting

Always consult with your doctor immediately to get best possible treatment if you are suffering from any of the above mentioned conditions.

## Things To Remember:

Keep the Crizalk 250 mg Capsule out of reach and sight of the children

This medicine is strictly not given for use in children and adolescents

You must always examine the information precisely written on the leaflet/ insert of the medicine

Always consult your medical doctor if you have any doubt in case of the dosage, time & strength of the medicine.

## Indications :

Crizalk 250 mg Capsule should be taken for cancer treatment. Do not take this medication for longer period than suggested by the Doctor.

## Storage :

Store the Crizalk 250 mg Capsule at room temperature in dark and dry place. Make sure the Capsules are intact and not damaged or broken while purchasing or storing.