Combimist-L Respules 2.5ml

Dr. Emily Brown

Dr. Ryan Mitchell

SKU

CMS3940

USA Brand Name

Combivent

Strength

1.25Mg + 500Mcg

Generic Name

Salbutamol / Albuterol + Ipratropium

Manufacturer

Zydus Cadila

## Combimist-L Respules 2.5 Ml (Salbutamol/ Albuterol & Ipratropium)

## What Is The Generic Name For Combimist-L Respules:

Salbutamol/ Albuterol & Ipratropium is the generic version for Combimist-L Respules

## Which USA Brand is Equivalent To Combimist-L Respules (Salbutamol/ Albuterol & Ipratropium):

Combivent

## About Combimist-L Respules (Salbutamol/ Albuterol & Ipratropium)

Combimist-L Respules contains two active ingredients, Salbutamol/ Albuterol & Ipratropium, which is used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Asthma is a disease which causes inflammation & narrowing of the air passage of the lungs (bronchi) which obstructs the airflow & makes breathing difficult. Chronic obstructive pulmonary disease is a kind of lung disorder in which there is difficulty in emptying air out of the lungs (airflow obstruction). Due to this obstruction, patients experience difficulty in breathing or get tired easily because of this breathing strain. COPD is a general term used for chronic bronchitis, emphysema, or a combination of both. This medicine is accessible at all the leading pharmacy, drugstores, & medical supply stores and must be taken strictly on doctor’s prescription only.

## Manufacturer:

Zydus Cadila Ltd. is one of the top pharmaceutical companies which manufacture Combimist-L Respules.

## Strength:

Combimist-L Respules contains two active constituents, Salbutamol/ Albuterol (1.25 mg) & Ipratropium (500 mcg). This medicine is obtainable in other substitutes also at all the leading online pharmacy, drugstores, & medical supply stores.

## What Are The Uses Of The Combimist-L Respules (Salbutamol/ Albuterol & Ipratropium):

Combimist-L Respules is used in the treatment in the following conditions:

Asthma

Chronic obstructive pulmonary disease

## How Combimist-L Respules (Salbutamol/ Albuterol & Ipratropium) Works:

Combimist-L Respules has two active ingredients; Salbutamol/ Albuterol and Ipratropium. Salbutamol /Albuterol is a long-acting bronchodilator that works by relaxing the muscles in the airways & expands the airways. Ipratropium is an anticholinergic which blocks the neurotransmitter acetylcholine in the central & the peripheral nervous system. Together, these make breathing easier.

## Before You Use Combimist-L Respules (Salbutamol/ Albuterol & Ipratropium):

Make certain that:

You are not sensitive to Salbutamol/ Albuterol & Ipratropium

You are not having any grave Disease

Your doctor must be educated about your medicinal history like your pre- existing disease, surgeries & Medications, Supplements, Food Habits, lifestyle, etc.

## What Should You Avoid While Taking Combimist-L Respules (Salbutamol/ Albuterol & Ipratropium):

You should avoid taking alcohol

You should avoid driving

You should avoid taking Medicines without prescriptions

## When Not To Use Combimist-L Respules (Salbutamol/ Albuterol & Ipratropium):

You should not take Combimist-L Respules if you:

Have ever noticed any Allergy/Hypersensitivity

Have liver problems

Have kidney problems

Have hypokalemia

Have glaucoma

Have urinary retention

Have Tachycardia

Have Paradoxical bronchospasm

Have decreased bone density

Are pregnant

Have infections

Are breastfeeding

## Tell Your Doctor If You:

Have Allergy to the Respules

Are taking Alcohol or Other Drugs

Have Liver disease

Have infections

## Dosage:

Combimist-L Respules contains two active ingredients, Salbutamol/ Albuterol & Ipratropium, which is used in the treatment of asthma & chronic obstructive pulmonary disease . This medicine is obtainable in different substitutes & strengths & has got to be purchased or given on doctor’s prescription only. You must discuss with your physician for adjustment of dosage & time of the medicine since age and severity of the disease differ from person to person and this can only be best judged by your doctor.

Adults are advised to take Combimist-L Respules at a fixed time with or without food as instructed by your Doctor. You must take Combimist-L Respules regularly on time for better results.

## How Much Of The Combimist-L Respules (Salbutamol/ Albuterol & Ipratropium) to Be Used:

As Combimist-L Respules is available in various strengths and substitutes, Patients are always advised to follow their doctor’s prescriptions and instructions to take Combimist-L Respules. You should not take the Respules on your own & for a longer period than recommended by the doctor.

## How To Take The Combimist-L Respules (Salbutamol/ Albuterol & Ipratropium):

Take Combimist-L Respules in the dose and duration as instructed by your doctor. You must read the label thoroughly for directions before use. Now twist off the top of the respule /transpule & squeeze all the liquid into the nebulizer. This should be used right away after opening. You must carry your rescue Respules wherever you go.

## For How Long Should You Continue Using Combimist-L Respules (Salbutamol/ Albuterol & Ipratropium):

You are always advised to take Combimist-L Respules as prescribed. Do not start/stop using this medicine on your own. You must strictly follow all the instructions given by your doctor. You should not take the Respules in larger or smaller quantity or for a longer period than suggested by your doctor.

## Overdose:

You have to seek medical emergency treatment and/ or contact your medical doctor instantly in case of any overdose symptoms. Emergency treatment will be initiated without delay by your medical doctor if they observe overdose symptoms.

## Missed Dose:

The missed dosage of the Respules should be administered as soon as possible. You should strictly skip the missed dosage if it is by now the time for your next planned dosage. It is advised not to double the dosage of the treatment to make up for the missed dosage.

## What Are The Side Effects Of The Combimist-L Respules (Salbutamol/ Albuterol & Ipratropium):

Nausea

Vomiting

Respiratory tract infection

Hoarseness of voice

Fungal infections in the mouth

Cough

Headache

Sore throat

Musculoskeletal (bone, muscle or joint) pain

Increased heart rate

Dizziness

Bladder pain

Wheezing

Nasal congestion

Blurred vision

Back pain

Shaking and trembling of arms and feet

Irregular heartbeat

Difficulty in breathing

Skin rash and spotting

Muscle pain and cramps

Sleep disturbances

Difficulty in passing urine

## What Are The Common Drug Interactions:

Some medicines have been reported to interact with Combimist-L Respules. These interactions might generate some needless or unfavorable effects and/or cause your drug not to act properly. You must always have a discussion with your doctor if you are taking other prescription/ Supplements so that well premeditated medication can be given. It interacts with the following medicines:

Amitriptyline

Atenolol

Ketoconazole

Mifepristone

Propranolol

Xylometazoline

Furosemide

Hydrochlorothiazide

Atropine

Insulin

Formoterol

Azithromycin

Aripiprazole

Clozapine

Chlorpheniramine

Tiotropium

It can also interact with the following disease condition:

Kidney Disease

Liver Disease

Heart disease

Diabetes

Hypokalemia

Seizures

## Warning And Precaution:

Combimist-L Respules can worsen the conditions like:

Allergy

Kidney/ Liver disease

Combimist-L Respules is not suggested for use in children less than 12 years of age

You have to use a reliable contraceptive method to avoid pregnancy while you are on this medication

You have to regularly get your blood tests done to examine your blood cells, liver and kidney function, and electrolyte levels during treatment with this medicine

Dry mouth may occur as a side effect of this medicine, so frequent mouth rinses, good oral hygiene, increased water intake & sugarless candy may help in this condition

You should not receive this medicine if you are pregnant, planning to conceive or breastfeeding

You must not drive or operate heavy machinery at the same time as taking this medicine as it may cause dizziness

Always discuss with your medical doctor straight away to get the most excellent possible treatment if you are observing any of the above mentioned conditions.

## Things To Remember:

Keep the Combimist-L Respules out of reach & sight of the children

This medicine is strictly used with vigilance for treatment of children

Combimist-L Respules is not recommended for use in pregnant women owing to the increased risk of harmful effects on the unborn baby

You must always check up the information in particular printed on the leaflet/ insert of the medicine

Always discuss with your medical doctor if you have any doubt in case of the dosage, time & strength of the medicine.

## Indications:

Combimist-L Respules should be taken as suggested by your doctor. Do not take this prescription for a longer period than recommended by the medical doctor.

## Storage:

Store the Combimist-L Respules at room temperature in dark & dry place. Make sure the Respules is intact & not broken while purchasing or storing.