Colstim 300 Mcg Prefilled Syringe

Dr. Emily Brown

Dr. Ryan Mitchell

SKU

CMS3844

USA Brand Name

Neupogen

Strength

300 Mcg

Generic Name

Filgrastim

Manufacturer

Zydus Cadila

## Colstim 300 Mcg Prefilled Syringe (Filgrastim)

## What Is The Generic Name For Colstim 300 Mcg Prefilled Syringe:

Filgrastim is the generic version for Colstim 300 mcg Prefilled Syringe

## Which USA Brand is Equivalent To Colstim 300 Mcg Prefilled Syringe (Filgrastim):

Neupogen

## About Colstim 300 Mcg Prefilled Syringe (Filgrastim)

Colstim 300 mcg Prefilled Syringe contains an active ingredient, Filgrastim , which is a human granulocyte colony-stimulating factor (G-CSF) analog. Filgrastim helps to stimulate the growth of white blood cells & helps in decreasing the likelihood of infection in patients which are undergoing chemotherapy treatment for cancer. Patients having blood disorders are advised not to use this medicine. This medicine is available at all the leading pharmacy, drugstores, & medical supply stores & must be taken strictly by doctor’s prescription only

## Manufacturer :

Zydus Cadila Ltd . is one of the leading pharmaceutical companies which manufacture Colstim 300 mcg Prefilled Syringe.

## Strength :

Colstim 300 mcg Prefilled Syringe contains an active constituent, Filgrastim (300 mg). It is obtainable in other substitutes also at all the leading online pharmacy, drugstores, and medical supply stores.

## What Are The Uses Of The Colstim 300 Mcg Prefilled Syringe (Filgrastim):

Colstim 300 mcg Prefilled Syringe is used in the treatment in following conditions:

Neutropenia caused by chemotherapy

Bone Marrow Transplantation

Peripheral Progenitor Cell Transplantation

Chronic Neutropenia

Neutropenia caused by radiation

## How Colstim 300 Mcg Prefilled Syringe (Filgrastim) Works:

Colstim 300 mcg Prefilled Syringe has an active ingredient; Filgrastim is a growth factor which stimulates the bone marrow to produce white blood cells. These cells protect the body from infections. Filgrastim drug is a human granulocyte colony stimulating factor (G-CSF) which is produced by recombinant DNA technology. As a G-CSF analog, Filgrastim controls the proliferation of committed progenitor cells & influences their maturation into full-grown neutrophils. Filgrastim as well stimulates the release of neutrophils from bone marrow storage pools & decreases their time to maturation. Filgrastim acts to boost the phagocytic activity of mature neutrophils, consequently allowing them to prevent infection. In patients receiving cytotoxic chemotherapy, filgrastim may speed up neutrophil recovery, leading to a decrease in the duration of the neutropenic phase post chemotherapy.

## Before You Use Colstim 300 Mcg Prefilled Syringe (Filgrastim):

Make sure that:

You are not allergic to Filgrastim

You are not having any serious Disease

Your doctor must be learned about your medicinal history like your pre- existing disease, surgeries & Medications, Supplements, Food Habits, lifestyle, etc.

## What Should You Avoid While Taking Colstim 300 Mcg Prefilled Syringe (Filgrastim):

You should avoid taking alcohol

You should avoid driving

You should avoid taking Medicines without prescriptions

## When Not To Use Colstim 300 Mcg Prefilled Syringe (Filgrastim):

You should not take Colstim 300 mcg Prefilled Syringe if you:

Have ever noticed any Allergy/Hypersensitivity

Have liver problems

Have kidney problems

Have Splenic Rupture

Have Acute Respiratory Distress Syndrome (ARDS)

Have Sickle cell crisis

Have blood disorder

Have decreased bone density

Are pregnant

Have infections

Are breastfeeding

## Tell Your Doctor If You:

Have Allergy to the Syringe

Are taking Alcohol or Other Drugs

Have Liver disease

Have infections

## Dosage :

Colstim 300 mcg Prefilled Syringe contains an active ingredient, Filgrastim, which is used in the treatment of infections after chemotherapy . This medicine is available in different substitutes & strengths & has got to be purchased or given on doctor’s prescription only. You must consult your physician for adjustment of dosage & time of the medicine because age and severity of the disease differ from person to person and it can only be best judged by your doctor.

Adults are advised to take Colstim 300 mcg Prefilled Syringe at a fixed time with or without food as instructed by your Doctor. You must take Colstim 300 mcg Prefilled Syringe regularly on time for better results.

## How Much Of The Colstim 300 Mcg Prefilled Syringe (Filgrastim) to Be Used:

As Colstim 300 mcg Prefilled Syringe is available in various strengths and substitutes, Patients are always advised to follow their doctor’s prescriptions and instructions to take Colstim 300 mcg Prefilled Syringe. You must not take the Syringe on your own & for longer period than recommended by doctor.

## How To Take The Colstim 300 Mcg Prefilled Syringe (Filgrastim):

Colstim 300 mcg Prefilled Syringe should be taken at a fixed time as directed by your doctor. Your doctor or nurse will give you Colstim 300 mcg Prefilled Syringe. Kindly do not self administer this medicine.

## For How Long Should You Continue Using Colstim 300 Mcg Prefilled Syringe (Filgrastim):

You are always advised to take Colstim 300 mcg Prefilled Syringe as prescribed. Do not start/stop using this medicine yourself. You must strictly follow all the directions given by your doctor. You must not take the Syringe in larger or smaller quantity or for longer period than suggested by your doctor.

## Overdose :

Seek medical emergency treatment and/ or contact your surgeon immediately in case of any overdose symptoms. Since Colstim 300 mcg Prefilled Syringe is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency measure will be initiated immediately by your physician if they observe overdose symptoms.

## Missed Dose:

The missed dosage of the Syringe should be administered by the doctor as soon as possible. It is strictly suggested to skip the missed dosage if it is already time for your next scheduled dosage. You must not double the dosage of the prescription to make up for the missed dosage. Since Colstim 300 mcg Prefilled Syringe is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dosage is very low.

## What Are The Side Effects Of The Colstim 300 Mcg Prefilled Syringe (Filgrastim):

Bone pain

Weakness

Headache

Rash

Nausea

Increased lactate dehydrogenase level in blood

Vomiting

Increased uric acid level in blood

Oropharyngeal pain

Hair loss

Fatigue

Diarrhea

Constipation

Decreased appetite

Cough

Breathing difficulty

Stomach pain

Fever and chills

Weight loss

Swelling or inflammation of mouth

## What Are The Common Drug Interactions:

Few medicines have been reported to interact with Colstim 300 mcg Prefilled Syringe. These interactions may generate some needless or adverse effects and/or cause your drug not to work properly. You must always have a conversation with your doctor if you are taking other prescription/ Supplements so that well planned medication can be given. It interacts with the following medicines:

Cisplatin

Fluorouracil

Doxorubicin

It can also interact with following disease condition:

Glomerulonephritis

Myeloid Tumors

Leukocytosis

## Warning And Precaution:

Colstim 300 mcg Prefilled Syringe can worsen the conditions like:

Allergy

Kidney/ Liver disease

You must not take this medicine if you are pregnant, planning to conceive or breastfeeding

You must not drive or operate heavy machinery at the same time as taking this medicine as it may cause dizziness

You must drink sufficient amount of water with this medicine

You must get regular tests done to monitor your bone density level while you are receiving treatment with this medicine

You must regularly get your blood tests done to monitor your blood cells, liver and kidney function, and electrolyte levels during treatment with this medicine

Always consult with your medical doctor straight away to get best possible treatment if you are observing any of the above mentioned conditions.

## Things To Remember:

Keep the Colstim 300 mcg Prefilled Syringe out of reach and sight of the children

This medicine is strictly used with carefulness for treatment of children

Colstim 300 mcg Prefilled Syringe is not recommended for use in pregnant women due to the increased risk of harmful effects on the unborn baby

You must always check up the information in particular printed on the leaflet/ insert of the medicine

Always consult your medical doctor if you have any uncertainty in case of the dosage, time & strength of the medicine.

## Indications :

Colstim 300 mcg Prefilled Syringe should be taken as recommended by your doctor. Do not take this prescription for longer period than suggested by the medical doctor.

## Storage:

Store the Colstim 300 mcg Prefilled Syringe at room temperature in a dark and dry place. Make sure the Syringe is intact & not damaged while purchasing or storing.