Adalat Crono 60 Mg (Nifedipine)
Price range: $76.74 through $161.04Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 40 Tablet/s | $76.74 | $1.92 / tablet | ||
| 80 Tablet/s | $121.39 | $1.52 / tablet | ||
| 120 Tablet/s | $161.04 | $1.34 / tablet |
About Adalat Crono 60 Mg (Nifedipine)
Medicine information
- Active ingredient
- Nifedipine
- Delivery time
- 10–14 business days after dispatch for the United States, United Kingdom, Canada, and Australia; estimates may be extended by customs or local carrier delays.
- Indication
- Treatment of hypertension and prophylaxis of chronic stable angina pectoris. Nifedipine prolonged-release formulations lower blood pressure by reducing peripheral vascular resistance and can improve coronary blood flow in patients with angina.
- Manufacturer
- Bayer S.p.A.
- Packaging
- 14 modified-release tablets in a daily calendar blister pack. The tablets are round, pink, coated tablets marked “ADALAT 60”.
- Strength
- 60 mg
- Dosage form
- Modified-release tablet
- Route
- Oral
Medicine overview
Adalat Crono 60 mg is an oral modified-release tablet containing 60 mg of nifedipine. It belongs to the dihydropyridine calcium-channel blocker class and is used to manage high blood pressure and prevent chronic stable angina. The modified-release formulation delivers nifedipine gradually rather than as an immediate-release dose. By relaxing arterial blood vessels, nifedipine reduces resistance against which the heart pumps and improves blood flow through the coronary circulation.
What it is used for
Adalat Crono 60 mg is used for the treatment of hypertension (high blood pressure) and for preventing chronic stable angina, a type of chest pain caused when the heart muscle does not receive enough oxygen-rich blood. It is intended for ongoing control rather than treatment of a sudden acute angina attack.
How it works
Nifedipine blocks calcium entry through slow calcium channels in vascular smooth-muscle cells. This relaxes and widens arteries. In hypertension, the resulting vasodilation reduces peripheral vascular resistance and lowers blood pressure. In stable angina, nifedipine reduces vascular resistance and dilates coronary arteries, helping improve coronary blood flow while reducing the workload against which the heart pumps. The prolonged-release formulation is designed to provide sustained nifedipine delivery.
How it is taken
Adalat Crono is taken by mouth. Swallow the modified-release tablet whole with water; do not bite, chew, crush, or break it because this can interfere with controlled release. Nifedipine prolonged-release tablets may be taken with or without food. Follow the prescribed schedule and do not change the dose without medical advice.
Important warnings
Do not use nifedipine if you are allergic to nifedipine or the product ingredients. Prolonged-release Adalat formulations are contraindicated in cardiogenic shock, clinically significant aortic stenosis, unstable angina, and during or within one month after myocardial infarction; they are not intended to treat an acute angina attack. Caution is required with very low blood pressure, poor cardiac reserve, and medicines that affect CYP3A4 metabolism. Rifampicin can markedly reduce nifedipine exposure and should not be used concurrently with this formulation. CYP3A4 inhibitors, including some macrolide antibiotics, azole antifungals, and HIV protease inhibitors, can increase nifedipine concentrations. Other blood-pressure-lowering medicines can produce an additive fall in blood pressure. The modified-release tablet must remain intact. Seek urgent medical attention for severe fainting or hypotension, breathing difficulty or swelling suggesting a serious allergic reaction, or new/worsening chest pain.
Side effects and monitoring
Common effects include headache, peripheral oedema such as ankle or leg swelling, vasodilation, constipation, and feeling unwell. Less common effects include dizziness, flushing-related symptoms, palpitations, fast heartbeat, low blood pressure, fainting, nausea, abdominal discomfort, indigestion, and allergic reactions. Rare or serious reactions can include angioedema involving the throat, severe allergic reactions, significant hypotension, intestinal obstruction, jaundice, and severe skin reactions. Blood pressure should be monitored during treatment, particularly when nifedipine is used with other medicines that lower blood pressure or alter its metabolism.
Pregnancy
Nifedipine should not be used during pregnancy unless the woman's clinical condition requires treatment with it. Use requires an individual assessment of benefits and risks. Careful blood-pressure monitoring is particularly important when nifedipine is given with intravenous magnesium sulfate because an excessive fall in blood pressure can occur.
Breastfeeding
Nifedipine passes into breast milk, although available clinical evidence indicates that the breastfed infant receives only a small fraction of the maternal dose. The decision to breastfeed while receiving nifedipine should consider both the benefit of breastfeeding and the benefit of treatment to the mother; medical advice is appropriate, particularly if signs of low blood pressure are suspected in the infant.
Food, drink and interactions
Alcohol may increase impairment such as dizziness or reduced reaction ability during nifedipine treatment, particularly when treatment is started or changed. Use caution and discuss alcohol intake with a healthcare professional if it causes dizziness or other blood-pressure-related symptoms.
Food and drink
The prolonged-release tablet can be taken with or without food. Avoid grapefruit and grapefruit juice while taking nifedipine. Grapefruit inhibits CYP3A4 metabolism and can increase nifedipine concentrations and its blood-pressure-lowering effect; after regular grapefruit consumption, this interaction can persist for at least three days after the last intake.
Storage
Store in the original packaging to protect the medicine from moisture. Keep out of the sight and reach of children, and do not use after the expiry date shown on the packaging.
Frequently asked questions
Can nifedipine 60 mg cause swollen ankles or feet?
Yes. Peripheral oedema, including ankle or leg swelling, is a common adverse effect of prolonged-release nifedipine. Contact your healthcare professional if swelling is troublesome, severe, sudden, or accompanied by other concerning symptoms.
Can Adalat Crono cause headaches when I first take it?
Yes. Headache is a common nifedipine side effect. Seek medical advice if a headache is severe, persistent, unusual, or accompanied by concerning symptoms.
Should I crush or split an Adalat Crono 60 mg tablet?
No. The modified-release tablet should be swallowed whole and must not be bitten, chewed, crushed, or broken because doing so can interfere with its controlled-release system.
Can I take Adalat Crono with grapefruit juice?
No. Grapefruit and grapefruit juice can increase nifedipine levels and strengthen its blood-pressure-lowering effect, so they should be avoided.
Why might something that looks like the tablet appear in my stool?
The insoluble outer components of this type of prolonged-release tablet can pass through the digestive tract and may appear in the stool after the nifedipine has been released. This can be expected with the delivery system.
Can I take Adalat Crono with food?
Yes. Prolonged-release nifedipine can be swallowed with water either with or without food.
Is Adalat Crono used to stop a sudden angina attack?
No. Prolonged-release Adalat is used to prevent chronic stable angina and should not be used to treat an acute angina attack.
Can Cheap Generic Med ship Adalat Crono to the United States?
Cheap Generic Med serves the United States under its international shipping model. Delivery is typically estimated at 10–14 business days after dispatch, but customs or carrier delays may extend transit. Prescription and personal-import requirements may apply.
Will a Cheap Generic Med order have tracking?
Under the standard fulfilment model, tracked international shipping is used and a tracking number should be provided after dispatch. Carrier systems may take 24–72 hours to begin showing movement.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Active Ingredients | Nifedipine |
|---|---|
| Manufacturer | Bayer Healthcare, Germany |
| Packaging | Qty |
| strength | 60mg |
| Delivery Time | 6 To 15 days |
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