Actinocin 0.5 Mg Injection (Dactinomycin)
Price range: $59.11 through $113.53Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 3 Injection | $59.11 | $19.70 / injection | ||
| 6 Injection | $86.70 | $14.45 / injection | ||
| 9 Injection | $113.53 | $12.61 / injection |
About Actinocin 0.5 Mg Injection (Dactinomycin)
Medicine information
- Active ingredient
- Dactinomycin
- Indication
- Antineoplastic treatment for Wilms tumor, rhabdomyosarcoma, Ewing sarcoma, metastatic nonseminomatous testicular cancer, gestational trophoblastic neoplasia, and regional perfusion of certain locally recurrent or locoregional solid malignancies. Dactinomycin is commonly used as part of combination cancer treatment.
- Strength
- 0.5 mg
- Dosage form
- Lyophilized powder for injection
- Route
- Intravenous
Medicine overview
Actinocin 0.5 Mg Injection contains dactinomycin, a cytotoxic antineoplastic medicine used in cancer chemotherapy. It is supplied as a 0.5 mg injectable preparation and is given by trained healthcare professionals. Dactinomycin is used for several cancers, including Wilms tumor, rhabdomyosarcoma, Ewing sarcoma, certain testicular cancers, and gestational trophoblastic neoplasia. Treatment is usually incorporated into a specialist oncology regimen that may also involve other chemotherapy medicines, surgery, or radiation therapy.
What it is used for
Dactinomycin is used in established cancer-treatment regimens for Wilms tumor, rhabdomyosarcoma, Ewing sarcoma, metastatic nonseminomatous testicular cancer, and gestational trophoblastic neoplasia. It may also be administered by regional perfusion for selected locally recurrent or locoregional solid malignancies. The exact role of dactinomycin depends on the cancer type and the specialist treatment protocol.
How it works
Dactinomycin is a cytotoxic actinomycin. It binds to DNA inside cells and inhibits the production of RNA, which cells need to make proteins and carry out normal growth processes. Cancer cells that are actively growing and dividing are therefore unable to reproduce normally. This cytotoxic effect helps suppress the growth of susceptible tumors, but it can also affect healthy rapidly dividing cells, which accounts for several of the medicine's important adverse effects.
How it is taken
Actinocin is an injectable cytotoxic medicine and should be prepared and administered only by appropriately trained healthcare professionals. Dactinomycin is given intravenously after reconstitution; dactinomycin may also be administered by regional perfusion for specific indications. The treatment schedule and amount administered depend on the cancer, treatment protocol, patient factors, and other therapies being used. Careful administration is essential because leakage outside the vein can cause severe tissue injury.
Important warnings
Dactinomycin can cause severe or fatal bone-marrow suppression, including neutropenia, thrombocytopenia, and anemia, so blood counts require monitoring. Severe or fatal hepatic veno-occlusive disease can occur, with particular risk reported in young children and with concomitant radiotherapy. Extravasation can cause severe local tissue damage, including blistering, ulceration, and persistent pain. Other major concerns include hepatotoxicity, renal toxicity, severe mucocutaneous reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis, secondary malignancies including leukemia, and increased radiation toxicity or radiation-recall reactions. Live viral vaccines are not recommended before or during treatment. Dactinomycin can cause fetal harm.
Side effects and monitoring
Common reported adverse reactions include nausea, vomiting, infection, hair loss, rash, difficulty swallowing, fatigue, fever, anemia, neutropenia, thrombocytopenia, mucositis, and liver toxicity. Serious complications include severe myelosuppression, hepatic veno-occlusive disease, kidney or liver injury, severe skin and mucosal reactions, and tissue injury following extravasation. Seek prompt medical attention for fever or signs of infection, unusual bleeding or bruising, jaundice, severe rash or blistering, or pain, redness, swelling, sores, or blistering around the injection site. Monitoring includes complete blood counts, liver tests, creatinine, and electrolytes.
Pregnancy
Dactinomycin can cause fetal harm based on its mechanism of action and animal reproduction data. Patients should tell their oncology team if they are pregnant or could become pregnant. Effective contraception is advised for females of reproductive potential during treatment and for 6 months after the final dose; male patients with female partners of reproductive potential are advised to use effective contraception during treatment and for 3 months after the final dose.
Breastfeeding
Breastfeeding is not recommended during dactinomycin treatment. Current prescribing information advises women not to breastfeed during treatment and for 14 days after the final dose.
Storage
Store at 20°C to 25°C (68°F to 77°F) and protect from light and humidity. Dactinomycin is a cytotoxic medicine and requires appropriate handling and disposal precautions. Product-specific storage requirements for reconstituted Actinocin should follow its supplied labeling.
Frequently asked questions
Why do I need blood tests while receiving dactinomycin?
Dactinomycin can suppress bone marrow and affect the liver and kidneys. Blood counts, liver tests, creatinine, and electrolytes may therefore be monitored during treatment.
Can dactinomycin damage the skin if it leaks from the vein?
Yes. Dactinomycin extravasation can cause severe tissue injury, including pain, blistering and ulceration. Tell the healthcare professional immediately if you notice pain, burning, redness, or swelling around the injection site.
Will dactinomycin make my hair fall out?
Hair loss is a recognized adverse effect of dactinomycin. Your oncology team can explain what to expect with the complete treatment regimen.
Can dactinomycin cause nausea or vomiting?
Yes. Nausea and vomiting are recognized adverse reactions. Your oncology team may use supportive medicines as part of your chemotherapy care.
Can I have vaccines while receiving dactinomycin?
Live viral vaccines are not recommended before or during dactinomycin treatment. Discuss any planned vaccination with your oncology team first.
Why does my doctor need to know about previous radiation treatment?
Dactinomycin can increase radiation-related toxicity and may trigger a radiation-recall reaction in tissue previously exposed to radiation. Your oncology team therefore needs an accurate history of radiation treatment.
Can Cheap Generic Med ship Actinocin to the United States?
Cheap Generic Med serves the United States under its international shipping model. Delivery is typically estimated at 10–14 business days after dispatch, although customs or carrier delays can extend transit. Prescription and import requirements may apply depending on the medicine and individual circumstances.
Will my Cheap Generic Med order have tracking?
Tracked international shipping is used under the standard fulfilment model. A tracking number should be provided after dispatch, although the carrier system may take 24–72 hours to begin showing movement.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Active Ingredients | Dactinomycin |
|---|---|
| Manufacturer | Neon Labs Ltd. |
| Packaging | Qty |
| strength | 0.5mg |
| Delivery Time | 6 To 15 days |
Related products
Erlonat 150 Mg (Erlotinib)
Irinotel 100 Mg/5 ml (Irinotecan)
Lomustine 40 Mg (Lomustine)
Mamofen 10 Mg (Tamoxifen Citrate)
Posid 50 Mg (Etoposid)
Progynova 1 Mg (Estradiol)
Sorafenat 200 Mg (Sorafenib)
Reviews
There are no reviews yet.