Acrotac 10 Mg (Acitretin)
Price range: $85.35 through $180.68Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 30 Capsule/s | $85.35 | $2.85 / capsule | ||
| 60 Capsule/s | $136.60 | $2.28 / capsule | ||
| 90 Capsule/s | $180.68 | $2.01 / capsule |
About Acrotac 10 Mg (Acitretin)
Medicine information
- Active ingredient
- Acitretin
- Indication
- Severe psoriasis in adults
- Manufacturer
- Sun Pharmaceutical Industries Ltd
- Strength
- 10 mg
- Dosage form
- Capsule
- Route
- Oral
Medicine overview
Acrotac 10 mg is an oral capsule containing acitretin, a systemic retinoid related to vitamin A. Acitretin is used for severe psoriasis in adults, particularly when systemic treatment is appropriate. It affects the abnormal growth and development of skin cells involved in psoriasis. Acitretin has important pregnancy, liver, lipid, and medicine-interaction warnings, so treatment requires medical supervision and regular monitoring.
What it is used for
Acitretin is indicated for severe psoriasis in adults. Because it can cause significant adverse effects, authoritative prescribing information states that it should be prescribed by clinicians experienced in the systemic use of retinoids. In females who can become pregnant, its use is particularly restricted because exposure during pregnancy can cause severe birth defects.
How it works
Acitretin belongs to the retinoid group of medicines, which are related to vitamin A. Retinoids influence the growth, maturation, and differentiation of skin cells. These effects can reduce the excessive skin-cell growth and thickening associated with psoriasis. The precise mechanism by which acitretin produces its therapeutic effects is not fully established.
How it is taken
Acitretin capsules are taken by mouth. They should be taken with food; official prescribing information specifies administration with the main meal because food improves absorption. The prescribed dose must be individualized according to clinical response and adverse effects, so patients should follow their prescriber's instructions rather than changing the dose themselves.
Important warnings
Acitretin can cause severe birth defects and must not be used during pregnancy. Females who can become pregnant must follow strict pregnancy-prevention requirements during treatment and for at least 3 years after stopping it. Acitretin is contraindicated in severe liver or kidney impairment and in patients with chronically abnormally elevated blood lipids. Methotrexate and tetracycline antibiotics are contraindicated with acitretin; vitamin A supplements and other oral retinoids should also be avoided because of additive toxicity. Liver injury, marked triglyceride elevation and pancreatitis, increased intracranial pressure, visual problems, serious skin reactions, and psychiatric symptoms have been reported. Seek prompt medical assessment for severe headache with nausea or visual changes, yellow skin or eyes, severe abdominal symptoms, major mood or behavioral changes, or a serious allergic reaction. Blood donation is prohibited during treatment and for at least 3 years afterward.
Side effects and monitoring
Common effects are largely related to retinoid activity and include dry or cracked lips, dry skin and mucous membranes, peeling or fragile skin, dry eyes, nose symptoms or nosebleeds, nail changes, and hair changes or hair loss. Acitretin can also increase triglycerides and cholesterol and affect liver function. Serious or less common problems include hepatitis, pancreatitis, increased intracranial pressure, severe skin reactions, impaired night vision, hypersensitivity, and reported psychiatric symptoms. Liver function and fasting blood lipids require monitoring; blood glucose may need particularly careful monitoring in people with diabetes. Pregnancy testing is essential for patients who can become pregnant.
Pregnancy
Acitretin is highly teratogenic and must not be used during pregnancy. Females who can become pregnant must avoid pregnancy during treatment and for at least 3 years after the final dose and must follow the required pregnancy-testing and contraception program. If pregnancy occurs during treatment or within this post-treatment period, urgent medical advice is required.
Breastfeeding
Do not breastfeed while taking acitretin. Acitretin has been reported in human milk, and prescribing information advises that nursing mothers should not receive it because of the potential for serious adverse reactions in the nursing infant.
Food, drink and interactions
Females who can become pregnant must not consume alcohol, including alcohol-containing drinks, foods, or medicines, while taking acitretin and for 2 months after stopping it. Ethanol can promote formation of etretinate, a highly teratogenic retinoid that remains in the body much longer than acitretin.
Food and drink
Take acitretin with food; absorption is optimal when it is administered with a meal. Avoid excessive vitamin A supplementation and other oral retinoids because combining them with acitretin can increase vitamin A-like toxicity. Females who can become pregnant must also avoid products containing alcohol during treatment and for 2 months afterward.
Storage
Store at controlled room temperature, generally 20°C to 25°C (68°F to 77°F). Protect the capsules from light and avoid exposure to high temperature and humidity after opening. Keep the medicine tightly closed and out of reach of children.
Frequently asked questions
Will acitretin make my lips and skin very dry?
Dry lips and skin are common with acitretin. Dryness can also affect the eyes and inside the nose; tell your prescriber if symptoms become severe or difficult to manage.
Can acitretin cause hair loss?
Yes. Hair loss or thinning can occur during acitretin treatment. Report troublesome or marked hair changes to your prescriber.
How long can acitretin take to improve psoriasis?
Improvement is not always immediate. Official prescribing information notes that some patients may improve within the first 8 weeks, while the full benefit can take about 2 to 3 months.
Do I need blood tests while taking acitretin?
Yes. Monitoring commonly includes liver-function tests and fasting blood lipids such as triglycerides and cholesterol. Additional monitoring may be required according to individual clinical circumstances.
Can I drink alcohol while taking acitretin?
Females who can become pregnant must avoid alcohol during treatment and for 2 months after stopping acitretin because alcohol can promote formation of long-lasting etretinate. Alcohol-containing foods and medicines also count.
Should Acrotac 10 mg be taken with food?
Yes. Acitretin is best absorbed with food, and prescribing information recommends taking it with the main meal.
Can I take vitamin A supplements with Acrotac?
Avoid additional vitamin A supplements unless specifically directed by your healthcare professional. Combining vitamin A or other oral retinoids with acitretin can increase vitamin A-like toxicity.
Why is pregnancy prevention required for so long after acitretin?
Acitretin can cause severe birth defects, and it can be converted into etretinate, which remains in the body for much longer. Pregnancy must therefore be avoided during treatment and for at least 3 years after treatment ends.
Can Cheap Generic Med ship Acrotac to the United States?
Cheap Generic Med serves the United States under its international shipping model. Delivery is typically estimated at 10–14 business days after dispatch, but customs or carrier delays can extend transit. Prescription and personal-import requirements may apply.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Active Ingredients | Acitretin |
|---|---|
| Manufacturer | Sun Pharmaceutical, India |
| Packaging | Qty |
| strength | 10mg |
| Delivery Time | 6 To 15 days |
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