Acivir 500 Mg Injection (Acyclovir)
Price range: $117.40 through $284.30Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 3 Injection | $117.40 | $39.13 / injection | ||
| 6 Injection | $201.30 | $33.55 / injection | ||
| 9 Injection | $284.30 | $31.59 / injection |
About Acivir 500 Mg Injection (Acyclovir)
Medicine information
- Active ingredient
- Acyclovir
- Delivery time
- 10-14 business days after dispatch for the United States, United Kingdom, Canada, and Australia; other destinations vary under the approved shipping framework. Delivery estimates are not guaranteed and customs or carrier delays may extend transit.
- Indication
- Treatment of serious herpesvirus infections, including mucosal and cutaneous herpes simplex infections in immunocompromised patients, severe initial genital herpes, herpes simplex encephalitis, neonatal herpes simplex infection, and varicella-zoster infection in immunocompromised patients.
- Manufacturer
- Cipla Ltd.
- Strength
- 500 mg
- Dosage form
- Injection
- Route
- Intravenous infusion
Medicine overview
Acivir 500 Mg Injection is an intravenous antiviral medicine containing 500 mg of acyclovir. It is manufactured by Cipla Ltd. and is used for serious infections caused by herpes viruses when intravenous treatment is appropriate. Acyclovir belongs to the synthetic nucleoside analogue class of antivirals. It limits viral replication rather than eliminating latent herpes virus from the body. The injection is administered into a vein under medical supervision.
What it is used for
Intravenous acyclovir is used for serious herpes simplex and varicella-zoster infections. Established indications include mucosal or skin herpes simplex infections in immunocompromised patients, severe initial genital herpes, herpes simplex encephalitis, neonatal herpes infection, and shingles caused by varicella-zoster virus in immunocompromised patients. The specific indication and treatment regimen depend on the infection and patient factors.
How it works
Acyclovir is activated preferentially inside herpesvirus-infected cells. Its active form interferes with viral DNA polymerase, an enzyme the virus needs to copy its genetic material. This interrupts viral DNA synthesis and limits further viral replication. The medicine is active against herpes viruses, including herpes simplex and varicella-zoster viruses, but it does not eradicate dormant virus from the body.
How it is taken
Acivir 500 Mg Injection is for intravenous use and should be prepared and administered by a healthcare professional. Intravenous acyclovir must be infused slowly; authoritative injection labeling specifies infusion over at least 1 hour and warns against rapid or bolus intravenous injection because this increases the risk of kidney injury. The required amount and treatment duration depend on the infection, body size, age, and kidney function.
Important warnings
Do not use acyclovir in patients with hypersensitivity to acyclovir or valacyclovir. Kidney injury, including renal failure, can occur, particularly with rapid infusion, inadequate hydration, impaired kidney function, or other nephrotoxic medicines. Renal function should be considered before and during treatment, and dosage adjustment may be necessary in renal impairment. Neurological reactions such as confusion, hallucinations, tremor, seizures, or encephalopathy have been reported, particularly in older adults or people with impaired renal function. Serious hypersensitivity reactions and severe skin reactions can also occur. Intravenous acyclovir must not be given by rapid bolus, intramuscular, or subcutaneous injection.
Side effects and monitoring
Commonly reported effects of intravenous acyclovir include inflammation or phlebitis at the infusion site, nausea, vomiting, and temporary increases in serum creatinine or blood urea nitrogen. Rash, itching, hives, and elevated liver enzymes can also occur. Serious or less common reactions include acute renal failure, anaphylaxis, severe local tissue injury after extravasation, seizures, confusion or encephalopathy, blood-cell abnormalities, hepatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis. Kidney function and clinical response may require monitoring. Seek urgent medical attention for markedly reduced urination, severe swelling, breathing difficulty, facial or throat swelling, severe rash, seizures, or significant changes in mental state.
Pregnancy
Systemic acyclovir has not shown a clear increase in birth defects in available pregnancy-registry data, but controlled pregnancy studies are limited. Intravenous acyclovir should be used during pregnancy when the expected clinical benefit justifies the potential fetal risk, as determined by the treating clinician.
Breastfeeding
Acyclovir passes into breast milk. Intravenous acyclovir can be used during breastfeeding when clinically appropriate, but professional assessment and infant monitoring are advised; suggested monitoring includes drowsiness, irritability, rash, vomiting, and diarrhoea.
Food and drink
There is no food-related administration requirement for an intravenous infusion. Maintaining adequate hydration is clinically important during intravenous acyclovir treatment because renal toxicity is a recognized risk, particularly when other risk factors are present.
Frequently asked questions
Can IV acyclovir affect my kidneys?
Yes. Intravenous acyclovir can cause kidney injury, particularly with rapid infusion, dehydration, impaired kidney function, or other nephrotoxic medicines. Kidney function and hydration therefore require attention during treatment.
Why does acyclovir injection have to be given slowly?
Slow intravenous infusion reduces the risk of acyclovir crystallizing in the kidney tubules and causing renal injury. Rapid or bolus intravenous administration should be avoided.
Is Acivir 500 Mg Injection the same as acyclovir tablets?
No. They contain the same antiviral active ingredient, but Acivir 500 Mg Injection is an intravenous dosage form used under medical supervision. Oral and intravenous products should not be treated as interchangeable.
Is IV acyclovir used for shingles?
Yes, in specific circumstances. Intravenous acyclovir is indicated for varicella-zoster infections such as shingles in immunocompromised patients.
What symptoms during IV acyclovir treatment need urgent medical attention?
Seek urgent medical care for reduced urination, severe swelling, difficulty breathing, facial or throat swelling, a severe or blistering rash, seizures, or significant confusion or other changes in mental state.
Does acyclovir completely cure herpes?
No. Acyclovir suppresses replication of herpes viruses and helps control an active infection, but it does not remove latent herpes virus from the body.
Will I get tracking if Cheap Generic Med ships my order?
Under the standard fulfilment model, tracked international shipping is used and a tracking number should be provided after dispatch. New tracking information may take 24-72 hours to show movement.
How is a Cheap Generic Med international order packaged?
The standard policy uses plain, discreet outer packaging without medicine details or pharmacy branding visible on the outside. Product-specific handling requirements still apply.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Active Ingredients | Acyclovir |
|---|---|
| Manufacturer | Cipla, India |
| Packaging | Qty |
| strength | 500mg |
| Delivery Time | 6 To 15 days |
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