Accufine 20 Mg Capsule (Isotretinoin)

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Pack SizePriceUnit PriceQuantity 
100 Capsule/s$95.00$0.95 / capsule
200 Capsule/s$150.00$0.75 / capsule
300 Capsule/s$195.00$0.65 / capsule
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Estimated delivery: October 5, 2026 – October 10, 2026
Written by Dr Ambrose Chan, MD, MD Medically reviewed by Dr. Sabrina Castillon, MD, MD
Last updated on September 11, 2026
Additional information
PackagingQty
Delivery Time6 To 15 days
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Description

About Accufine 20 Mg Capsule (Isotretinoin)

Medicine information

Active ingredient
Isotretinoin
Delivery time
Typically 10–14 business days after dispatch for the United States, United Kingdom, Canada, and Australia; other destinations vary. These are estimates and customs or local carrier delays may extend delivery.
Indication
Severe acne that has not responded adequately to standard treatments, including severe nodular, conglobate, or scarring-risk acne.
Manufacturer
Healing Pharma India Pvt Ltd
Strength
20 mg
Dosage form
Soft gelatin capsule
Route
Oral

Medicine overview

Accufine 20 Mg is an oral soft gelatin capsule containing 20 mg of isotretinoin, a retinoid related to vitamin A. It is manufactured by Healing Pharma India Pvt Ltd and is used for severe or treatment-resistant acne. Isotretinoin reduces several processes involved in acne, particularly excessive production of sebum, the oily substance made by sebaceous glands. Because isotretinoin can cause serious adverse effects, especially severe harm to an unborn baby, treatment requires medical supervision and appropriate monitoring.

What it is used for

Accufine 20 Mg is used to treat severe forms of acne when adequate standard treatment, such as systemic antibiotics and topical acne therapy, has not worked. Appropriate cases can include severe nodular or conglobate acne and acne associated with a substantial risk of permanent scarring. Isotretinoin is generally reserved for severe disease because its safety risks and monitoring requirements are greater than those of many routine acne treatments.

How it works

Isotretinoin is a systemic retinoid that acts on several processes involved in acne. Its most important effect is a marked reduction in the activity and size of sebaceous glands, which lowers production of sebum. It also helps normalize the way skin cells develop around hair follicles and has anti-inflammatory effects. Together, these actions reduce blocked pores and make the skin environment less favorable for acne-associated bacterial growth, helping severe inflammatory acne improve.

How it is taken

Take Accufine 20 Mg only according to the prescription and instructions provided by the treating clinician. Swallow the capsule whole with liquid; do not chew, crush, or suck it. Conventional isotretinoin capsules are taken with food, and the exact daily amount and treatment duration are determined individually. If a dose is missed, skip it rather than taking two doses together. Do not change the prescribed dose or treatment schedule without medical guidance.

Important warnings

Isotretinoin is contraindicated during pregnancy because exposure can cause severe, potentially life-threatening birth defects and pregnancy loss. Patients who can become pregnant require appropriate pregnancy prevention and testing before, during, and after treatment according to applicable local requirements. Do not use isotretinoin with vitamin A supplements, and avoid concurrent tetracycline antibiotics because of the risk of intracranial hypertension. Tell the prescriber about liver disease, abnormal blood lipids, diabetes, mental health problems, and all medicines or supplements being used. Liver function and fasting lipid levels require monitoring. Seek prompt medical attention for severe headache with nausea or visual changes, significant mood or behavioral changes, severe abdominal pain, rectal bleeding or severe diarrhea, sudden hearing or vision problems, or a severe skin reaction. Blood donation should be avoided during treatment and for the required period afterward.

Side effects and monitoring

Common effects include very dry or cracked lips, dry skin, dry eyes, nosebleeds, headache, back or joint pain, dermatitis, and other musculoskeletal discomfort. Serious or less common problems include liver injury, marked triglyceride elevation and pancreatitis, intracranial hypertension, severe skin reactions, hearing or visual disturbances, and psychiatric symptoms. Contact a clinician promptly if serious symptoms develop. Liver function tests and fasting lipid levels should be checked before treatment and monitored as clinically appropriate; patients who can become pregnant also require pregnancy testing.

Pregnancy

Do not use isotretinoin during pregnancy. It is a powerful teratogen, meaning it can cause severe birth defects, and exposure is also associated with miscarriage and premature birth. Patients who can become pregnant need pregnancy testing and effective pregnancy prevention before, during, and after treatment according to the applicable pregnancy-prevention program. If pregnancy occurs or is suspected during treatment, stop taking isotretinoin and contact the prescribing clinician immediately.

Breastfeeding

Breastfeeding is not recommended while taking isotretinoin because of the potential for serious adverse reactions in a nursing infant. The required period for avoiding breastfeeding after the final dose can differ between approved product labels, so follow the instructions supplied with the prescribed product and the treating clinician's advice.

Food, drink and interactions

It is best to avoid alcohol or keep consumption to a minimum during isotretinoin treatment. Isotretinoin can increase triglycerides and affect liver function, and alcohol can add to these concerns. Patients who drink alcohol regularly should tell their prescriber because closer laboratory monitoring may be appropriate.

Food and drink

Conventional isotretinoin capsules should be taken with food to support absorption. Swallow the capsule whole with water or another suitable liquid. Follow the instructions for the specific prescribed product rather than adding unusually large quantities of dietary fat.

Frequently asked questions

Do I need to take Accufine 20 Mg with food?

Yes. Conventional isotretinoin capsules should be taken with food because food improves absorption. Follow the specific instructions provided with your prescribed product.

Are very dry lips and skin normal with isotretinoin?

Yes. Dry or cracked lips and dry skin are among the most common isotretinoin side effects. Tell your clinician if dryness becomes severe or is accompanied by a significant rash or other concerning symptoms.

Can my acne get worse after starting isotretinoin?

Acne can occasionally worsen during the early part of treatment. Do not change the dose yourself; contact the prescribing clinician if the flare is severe or you are concerned about your response.

Can I drink alcohol while taking Accufine 20 Mg?

It is best to avoid alcohol or reduce it substantially. Both alcohol use and isotretinoin can be relevant to liver function and blood triglyceride levels, which are monitored during treatment.

Why do I need blood tests while taking isotretinoin?

Isotretinoin can increase blood lipids, particularly triglycerides, and can affect liver enzymes. Fasting lipid and liver-function testing helps the prescriber identify clinically important changes.

Can I take vitamin A supplements with Accufine 20 Mg?

No. Vitamin A supplements should be avoided with isotretinoin because combining them can increase vitamin A-type toxicity. Tell your clinician about vitamins and supplements before treatment.

Can Accufine 20 Mg be used during pregnancy?

No. Isotretinoin is contraindicated during pregnancy because it can cause severe birth defects and pregnancy loss. Strict pregnancy-prevention requirements apply to patients who can become pregnant.

Does Cheap Generic Med ship Accufine 20 Mg to the United States?

Cheap Generic Med serves the United States under its international shipping model. Delivery is typically estimated at 10–14 business days after dispatch, although customs or carrier delays can extend transit; shipping availability does not establish that personal import is legally permitted in every circumstance.

Will my Accufine order have tracking?

Under the standard international fulfilment model, tracked shipping is used and a tracking number should be provided after dispatch. New tracking information can take 24–72 hours to begin showing movement in the carrier system.

Sources

  1. www.healingpharma.in
  2. dailymed.nlm.nih.gov
  3. medlineplus.gov
  4. www.medicines.org.uk
  5. www.medicines.org.uk

Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.