Adalat Crono 30 Mg (Nifedipine)
Price range: $56.71 through $104.88Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 40 Tablet/s | $56.71 | $1.42 / tablet | ||
| 80 Tablet/s | $82.22 | $1.03 / tablet | ||
| 120 Tablet/s | $104.88 | $0.87 / tablet |
About Adalat Crono 30 Mg (Nifedipine)
Medicine information
- Active ingredient
- Nifedipine
- Delivery time
- United States, United Kingdom, Canada and Australia: typically 10–14 business days after dispatch. Europe: typically 12–18 business days. Other served destinations generally 14–21 business days. These are estimates and customs or local carrier delays may extend delivery.
- Indication
- Treatment of arterial hypertension and chronic stable angina pectoris (effort angina).
- Manufacturer
- Bayer AG
- Packaging
- 14 or 28 modified-release tablets in blister packs
- Strength
- 30 mg
- Dosage form
- Modified-release tablet
- Route
- Oral
Medicine overview
Adalat Crono 30 mg is a modified-release nifedipine tablet used to treat high blood pressure and chronic stable angina. Nifedipine belongs to the dihydropyridine calcium-channel blocker class. It relaxes arterial blood vessels, reducing resistance against which the heart pumps and improving blood flow. The modified-release formulation is designed to release nifedipine gradually, allowing prolonged action rather than the rapid release produced by immediate-release nifedipine formulations.
What it is used for
Adalat Crono 30 mg is used for the treatment of arterial hypertension, where lowering elevated blood pressure helps control the condition. It is also indicated for chronic stable angina pectoris, sometimes called effort angina. In this condition, nifedipine reduces the workload on the heart and improves coronary blood flow. The modified-release formulation is intended for ongoing treatment and is not suitable for treating a sudden acute angina attack.
How it works
Nifedipine blocks L-type calcium channels in vascular smooth muscle. Calcium entering these cells normally contributes to contraction of the arteries. By reducing calcium entry, nifedipine relaxes and widens arterial blood vessels. This lowers peripheral vascular resistance and therefore blood pressure. Dilatation of coronary arteries and reduced cardiac workload also help prevent symptoms of chronic stable angina. Adalat Crono uses a controlled-release system to deliver nifedipine gradually over an extended period.
How it is taken
Take Adalat Crono by mouth exactly as prescribed. Modified-release nifedipine tablets are generally swallowed whole with water and should not be bitten, chewed, crushed or broken because this can interfere with controlled release. They may be taken with or without food. Take the medicine consistently at approximately the same time each day. Avoid grapefruit and grapefruit juice during treatment. Do not use the tablet to treat a sudden angina attack.
Important warnings
Do not use Adalat Crono if you are allergic to nifedipine or other dihydropyridines. Modified-release nifedipine is contraindicated in conditions including cardiogenic shock and clinically significant aortic stenosis, and certain product information also contraindicates use with unstable angina or during or shortly after myocardial infarction. It must not be taken with rifampicin because rifampicin can substantially reduce nifedipine exposure. Nifedipine is affected by CYP3A4 inhibitors and inducers, including some macrolide antibiotics, azole antifungals, HIV protease inhibitors, phenytoin, carbamazepine and phenobarbital. Other blood-pressure medicines can increase its hypotensive effect. Extra caution is required with very low blood pressure, heart failure, impaired liver function and certain gastrointestinal narrowing or obstruction disorders. Seek urgent medical care for severe fainting, difficulty breathing, swelling of the face or throat, or new or worsening chest pain.
Side effects and monitoring
Common effects include headache, peripheral oedema or ankle swelling, flushing or other vasodilatation, constipation and feeling unwell. Dizziness, low blood pressure, fainting, palpitations, rapid heartbeat, nausea, indigestion, abdominal discomfort and visual disturbances occur less commonly. Serious reactions can include severe allergic reactions or angioedema, marked hypotension, worsening chest pain and severe skin reactions. Blood pressure should be monitored during treatment, particularly when interacting medicines are started or stopped. Liver function and clinical response may require closer observation in patients with hepatic impairment.
Pregnancy
Nifedipine should not be used during pregnancy unless the woman's clinical condition requires it. Available product information recommends a careful individual assessment of benefits and potential risks, particularly because available evidence cannot completely exclude effects on the fetus or newborn. Blood pressure requires careful monitoring when nifedipine is used with intravenous magnesium sulfate because an excessive fall in blood pressure may occur.
Breastfeeding
Nifedipine passes into breast milk, although available clinical evidence indicates that the breastfed infant receives only a small fraction of the maternal dose. The decision whether to breastfeed during treatment or use an alternative therapy should consider the benefit of breastfeeding to the child and the importance of nifedipine treatment to the mother. Medical advice is recommended, particularly if the infant shows possible signs of low blood pressure.
Food, drink and interactions
Alcohol may increase dizziness or other effects that impair driving or operating machinery, particularly when nifedipine treatment is started or changed. Use caution with alcohol and discuss alcohol intake with the prescribing healthcare professional if dizziness or low blood pressure occurs.
Food and drink
Adalat modified-release tablets can generally be taken with or without food. Avoid grapefruit and grapefruit juice because they inhibit CYP3A4 and can increase nifedipine concentrations, potentially strengthening and prolonging its blood-pressure-lowering effect. After regular grapefruit consumption, this interaction can persist for several days.
Storage
Keep the tablets in their original packaging to protect them from light and moisture. Nifedipine is light-sensitive, so remove a tablet from its blister only immediately before use and do not break the tablet. Do not store above 30°C where specified by the product information. Keep medicines out of the sight and reach of children.
Frequently asked questions
Can ankle swelling happen with nifedipine?
Yes. Peripheral oedema, often noticed as swelling around the ankles or lower legs, is a recognised common adverse effect of modified-release nifedipine. Contact your healthcare professional if swelling is troublesome, severe or accompanied by breathing difficulty.
Can Adalat Crono make me feel dizzy?
Yes. Nifedipine can lower blood pressure and may cause dizziness, particularly when treatment begins or when other blood-pressure-lowering medicines are used. Avoid driving or operating machinery if you feel affected.
Why can I sometimes see what looks like the tablet in my stool?
Some controlled-release nifedipine formulations leave an insoluble tablet shell after the medicine has been released. The empty shell can pass in the stool and does not by itself mean that the dose was not absorbed.
Can I crush or split Adalat Crono 30 mg?
No. The modified-release tablet should be swallowed whole and should not be bitten, chewed, crushed or broken because doing so can interfere with its controlled-release system.
Can I drink grapefruit juice while taking nifedipine?
No. Grapefruit and grapefruit juice can increase nifedipine levels by interfering with CYP3A4 metabolism, which may increase its blood-pressure-lowering effect. The interaction can persist for several days after regular grapefruit consumption stops.
What should I do if I develop chest pain while taking Adalat Crono?
New, worsening or severe chest pain requires prompt medical assessment. Adalat Crono is used to prevent chronic stable angina and should not be used as a treatment for an acute angina attack.
Can Cheap Generic Med ship Adalat Crono to the United States?
Cheap Generic Med serves the United States under its international shipping model, with delivery typically estimated at 10–14 business days after dispatch. Customs or carrier delays can extend transit, and prescription and personal-import requirements may apply.
Will my Adalat Crono order have tracking?
Under Cheap Generic Med's standard international fulfilment model, tracked shipping is used and a tracking number should be provided after dispatch. New tracking numbers may take 24–72 hours to begin showing movement.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Packaging | Qty |
|---|---|
| Delivery Time | 6 To 15 days |
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