Acuitel 5 Mg (Quinapril Hydrochloride)
Price range: $63.06 through $77.04Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 60 Tablet/s | $63.06 | $1.05 / tablet | ||
| 80 Tablet/s | $69.94 | $0.87 / tablet | ||
| 100 Tablet/s | $77.04 | $0.77 / tablet |
About Acuitel 5 Mg (Quinapril Hydrochloride)
Medicine information
- Indication
- Essential hypertension; cardiac failure as adjunctive treatment to diuretics and, particularly in serious cardiac failure, digitalis.
- Manufacturer
- Pfizer Manufacturing Deutschland GmbH, Betriebsstätte Freiburg, Germany.
- Packaging
- Polyamide/aluminium/PVC and aluminium-foil blister packs. Acuitel 5 is listed in packs of 30 and 100 film-coated tablets; not all pack sizes may be marketed.
- Dosage form
- Film-coated tablet; scored and can be divided into equal doses.
Medicine overview
Acuitel 5 is a film-coated tablet containing quinapril hydrochloride equivalent to 5 mg quinapril. Quinapril belongs to the angiotensin-converting enzyme (ACE) inhibitor class. It is used to treat essential hypertension and may also be used as adjunctive treatment in cardiac failure. By reducing the formation of angiotensin II, a substance that narrows blood vessels, quinapril helps blood vessels relax and lowers resistance against which the heart pumps.
What it is used for
Acuitel is indicated for essential hypertension, meaning high blood pressure without a specific secondary cause. It is also indicated as adjunctive medication for cardiac failure alongside diuretics and, particularly in serious cardiac failure, digitalis. Treatment and dose selection require medical supervision, especially in people with impaired kidney function, fluid or salt depletion, or other conditions that increase the risk of excessive blood-pressure reduction.
How it works
Quinapril is converted in the body to quinaprilat, which inhibits angiotensin-converting enzyme (ACE). ACE normally helps produce angiotensin II, a substance that constricts blood vessels and promotes aldosterone secretion. Reducing angiotensin II allows blood vessels to relax and lowers peripheral vascular resistance. In hypertension this reduces blood pressure, while in cardiac failure the reduced resistance and cardiac workload can support the heart's pumping function.
How it is taken
Acuitel is taken by mouth and can be taken independently of meals. The prescribed daily amount may be taken as a single dose or divided into two doses, depending on the treatment plan. The 5 mg tablet can be divided into equal doses. Dose selection and treatment duration should be determined by the treating clinician, with particular care in older adults, people with kidney impairment, and patients at risk of low blood pressure.
Important warnings
Do not use Acuitel in people with hypersensitivity to quinapril or its ingredients, a history of angioedema associated with ACE inhibitors, or during pregnancy. Concomitant sacubitril/valsartan is contraindicated because of the increased risk of angioedema; a 36-hour separation is required when switching between these treatments. Aliskiren must not be combined with quinapril in patients with diabetes or relevant renal impairment. Quinapril can cause symptomatic hypotension, deterioration in kidney function, and increased potassium. NSAIDs, potassium supplements or potassium-sparing medicines, lithium, diuretics, and other medicines affecting the renin-angiotensin system require particular attention. Seek urgent medical care for swelling of the face, lips, tongue or throat, difficulty breathing or swallowing, or other signs of severe angioedema. Kidney function, blood pressure and electrolytes require appropriate monitoring.
Side effects and monitoring
Common effects reported with Acuitel include cough or irritative cough, headache, dizziness, fatigue or weakness, nausea, vomiting, diarrhoea, abdominal discomfort, indigestion, back or muscle pain, skin reactions, and excessive lowering of blood pressure, particularly in susceptible patients. Serious or less common problems include angioedema, severe hypotension or fainting, hyperkalaemia, acute deterioration in kidney function, severe skin reactions, blood-cell abnormalities, pancreatitis and liver injury. Urgent assessment is needed for facial or throat swelling, breathing difficulty, fainting, jaundice, or a severe skin reaction. Monitoring may include blood pressure, kidney function, serum creatinine and electrolytes, particularly potassium; blood counts may also be monitored in higher-risk patients.
Pregnancy
Acuitel is contraindicated during pregnancy. ACE inhibitors can cause fetal toxicity, particularly with exposure during the second and third trimesters, including impaired fetal kidney function, oligohydramnios, delayed skull ossification, neonatal hypotension, hyperkalaemia, renal failure and potentially death. If pregnancy occurs, quinapril treatment should be stopped promptly under medical supervision and an appropriate alternative considered.
Breastfeeding
Acuitel should not be used while breastfeeding premature infants or during the first weeks after delivery because potential cardiovascular and kidney effects in the infant cannot be excluded and clinical experience is limited. The product information reports only very low quinapril concentrations in human milk, but breastfeeding use still requires medical assessment.
Food, drink and interactions
Alcohol can increase the effects of alcohol itself and may enhance orthostatic hypotension, causing a greater fall in blood pressure when standing. Caution with alcohol is therefore advised while taking Acuitel, particularly if dizziness or light-headedness occurs.
Food and drink
Acuitel can be taken independently of meals; food does not materially affect quinapril absorption. High dietary salt intake may reduce its blood-pressure-lowering effect. Potassium-containing supplements or salt substitutes require medical advice because quinapril can increase blood potassium.
Storage
Keep in a dry place and do not store above 25°C. Keep out of the sight and reach of children. Do not use after the expiry date printed on the carton or blister.
Frequently asked questions
Can quinapril cause a dry cough?
Yes. A persistent, non-productive cough is a recognised effect of ACE inhibitors, including quinapril. If a cough develops and remains troublesome, discuss it with the prescribing clinician rather than changing treatment yourself.
Can Acuitel make me feel dizzy when I stand up?
Yes. Quinapril can lower blood pressure enough to cause dizziness, weakness or light-headedness, particularly when treatment begins or in people who are dehydrated, taking diuretics or otherwise salt- or fluid-depleted.
Does quinapril affect potassium levels?
Yes. Quinapril can increase blood potassium. Potassium supplements, potassium-containing salt substitutes and potassium-sparing medicines should not be added without medical advice, and potassium may need monitoring during treatment.
Do I need kidney tests while taking Acuitel?
Kidney function should be assessed before treatment and monitored when clinically appropriate. Closer monitoring is particularly important in people with kidney impairment and those taking medicines that can affect kidney function or potassium.
Can Acuitel 5 be taken with food?
Yes. Acuitel can be taken independently of meals, and food does not significantly affect quinapril absorption.
Can I drink alcohol while taking Acuitel?
Alcohol can increase the risk of a blood-pressure drop when standing and may worsen dizziness or light-headedness. Use caution and follow advice from your healthcare professional.
What should I do if my face or lips swell while taking Acuitel?
Seek urgent medical attention. ACE inhibitors can rarely cause angioedema, which may involve the face, lips, tongue or throat and can interfere with breathing.
Can Cheap Generic Med ship Acuitel to the United States?
Cheap Generic Med serves the United States under its international shipping model. Delivery for international orders to the United States is typically estimated at 10–14 business days after dispatch, but customs or carrier delays can extend transit; shipping availability does not establish that personal import is legally permitted.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Active Ingredients | Quinapril Hydrochloride |
|---|---|
| Manufacturer | Pfizer |
| Packaging | Qty |
| strength | 5mg |
| Delivery Time | 6 To 15 days |
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