Cobix 200 Mg

Dr. Emily Brown

Dr. Ryan Mitchell

SKU

CMS515

USA Brand Name

Celebrex

Strength

200mg

Generic Name

Celecoxib

Manufacturer

Cipla, India

## Cobix 200 Mg

## About the brand

Celecoxib 200 is marketed by Cipla Laboratories. The active ingredient of cobix 200 is celecoxib . Cobix 200 is primarily used for relieving the signs and symptoms of Acute pain or primary dysmenorrheal, Ankylosing spondylitis, Osteoarthritis and Rheumatoid arthritis.

## USA Brands Equivalent to Celecoxib the salt in Coxib 200

Celebrex is USA brand equivalent to cobix 200

## The drug is primarily used for

Ankylosing spondylitis: It is a type of arthritis affecting spine. This may result in pain and inflammation of joints. Celecoxib reduces pain and inflammation by inhibiting the production of prostaglandin precursors.

Osteoarthritis : It is a joint disease resulting from breakdown of joint cartilage and underlying bone tissue. Celecoxib produces a significant improvement in pain and inflammation.

Rheumatoid arthritis: It is a common type of autoimmune disorder. Pain and swollen joints are the most common signs of this disease. Celecoxib is frequently used to help with symptoms.

## How cobix 200 works?

The drug mainly acts by inhibiting prostaglandin synthesis by decreasing the activity of the enzyme, cyclooxygenase -2 (COX-2), which results in decreased formation of prostaglandin precursors; and this further results in antipyretic, analgesic, and anti-inflammatory properties. Celecoxib does not inhibit cyclooxygenase-1 (COX-1) at therapeutic concentrations.

## Manufacturer of cobix 200

Cobix 200 having 200 mg of Celecoxib is manufactured primarily by Cipla Laboratories. It is mainly marketed and supplied by the company and its associates in India.

Strength and Dosage of Cobix 200

Strength Cobix 200 having 200 mg of Celecoxib .

Dosage Celecoxib the active salt in Cobix 200 is to be taken in dosage which ranges from 100 mg to 400 mg. More specific dose will be directed by your doctor. Hence, cobix 200 should not be taken without doctor’s consultation.

## How to take cobix 200 ?

Cobix 200 having salt Celecoxib can be administered with/ without regards to meals, if you have any ingestion problems then take the medicine with food. Capsules may be swallowed whole or the entire contents emptied onto a teaspoon of cool or room temperature applesauce and administered immediately with water. The contents of the capsules sprinkled onto applesauce may be stored under refrigeration for up to 6 hours.

## Adverse Effects/ Side Effects

Allergic side effects may result in some patients. It depends upon person to person. Inform your doctor if you have any specific effects after using the drug (Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.)

## Common Gastrointestinal Side Effects Of Cobix 200 are:

Loose stools, the fullness of stomach, abdominal pain, vomiting, and heartburn feeling.

Respiratory side effects are Upper respiratory tract infection, sinusitis, sore throat, stiffness of nose, shortness of breath and cough. Other side effects include:

Depression

Weakness

Hearing loss

Headache

Dizziness

Increased liver enzymes(serum alkaline phosphatase, serum transaminases)

Ringing in ears

Chances for bleeding is increased

Weight gain

Call your doctor right away if you have any deadly side effects

## How long should cobix 200 be continued?

Cobix having Celecoxib is need to basis medicine. Consult your doctor regarding the intake and stoppage of the drug. Do not take a decision on your own. Consult a doctor for each possible step.

## Overdose Effects of CELECOXIB the salt in Cobix 200

Possible side effects of over dosage vary from person to person. However, the long term use of this drug may increase the risk of heart problems and chances for stroke and gastrointestinal bleeding. If overdose of the drug occurred contact with your doctor immediately.

## Dose of Cobix 200 missed

The possible chances of missing the dose of the drug is minimal, however, consult your doctor regarding the same. Take the missed dose as soon as you remember it.

## Drug Interactions with Cobix 200 Drug

Tell your doctor if you are using any of these drugs

If you are taking any other NSAID.

If you are taking a salicylate drug like aspirin.

If you are taking methotrexate

If you are taking Nitric oxide

If you are taking tacrolimus, ciclosporin

If you are taking fluconazole, rifampicin

If you are taking ACE inhibitors, beta-blockers and diuretics

If you are taking barbiturates, carbamazepine

Also, pre inform your doctor

If you have an allergy to celecoxib or any other ingredient of this drug.

If you have an allergy to aspirin or NSAIDs

If you have any heart, kidney problems

If you have gastrointestinal bleeding

Hypersensitivity to sulphonamides

Do not take Cobix 200 if you have allergic reactions with the salt or excipients’ such as lactose present in the drug.

If you have gastrointestinal bleeding.