Abirapro 500 Mg Tablet (Abiraterone Acetate)
Price range: $518.28 through $1,380.00Required
| Pack Size | Price | Unit Price | Quantity | |
|---|---|---|---|---|
| 1 Bottle/s | $518.28 | $518.28 / bottle | ||
| 2 Bottle/s | $964.06 | $482.03 / bottle | ||
| 3 Bottle/s | $1,380.00 | $460.00 / bottle |
About Abirapro 500 Mg Tablet (Abiraterone Acetate)
Medicine information
- Active ingredient
- Abiraterone acetate
- Indication
- Metastatic castration-resistant prostate cancer (mCRPC) in adult men. Abiraterone acetate is used as part of androgen-deprivation treatment and with a corticosteroid such as prednisone or prednisolone.
- Manufacturer
- Glenmark Pharmaceuticals Limited
- Packaging
- 60 tablets
- Strength
- 500 mg
- Dosage form
- Tablet
- Route
- Oral
Medicine overview
Abirapro 500 mg is an oral anticancer medicine from Glenmark Pharmaceuticals Limited containing abiraterone acetate. It belongs to the androgen-biosynthesis inhibitor class and is used in the treatment of advanced prostate cancer. Abiraterone acetate is converted in the body to abiraterone, which reduces production of androgen hormones that can stimulate prostate-cancer growth. Treatment is normally combined with a corticosteroid and continued androgen-deprivation therapy when medically appropriate.
What it is used for
Abirapro is used for advanced prostate cancer, with Glenmark information specifically supporting use of the Abirapro brand in metastatic castration-resistant prostate cancer. Abiraterone acetate is generally given with prednisone or prednisolone and, in patients who have not undergone surgical removal of the testes, alongside ongoing medical androgen-deprivation therapy. The exact approved indications for the Abirapro 500 mg presentation can depend on its local product authorization.
How it works
Abiraterone acetate is converted to abiraterone after administration. Abiraterone blocks CYP17, an enzyme involved in producing androgen hormones such as testosterone. Androgens can promote the growth of many prostate cancers. By reducing androgen production in the testes, adrenal glands and prostate-tumour tissue, abiraterone lowers hormonal stimulation available to the cancer and can help slow disease progression.
How it is taken
Take Abirapro only according to the prescribing oncology team's instructions. Standard abiraterone acetate tablets are taken by mouth on an empty stomach; food should be avoided for at least 2 hours before and 1 hour after the dose because food can substantially increase drug exposure. Swallow tablets whole with water and do not crush or chew them. Abiraterone is normally used with a prescribed corticosteroid such as prednisone or prednisolone. Do not alter or stop either medicine without medical guidance.
Important warnings
Abiraterone can cause high blood pressure, low potassium levels and fluid retention because of excess mineralocorticoid activity. Blood pressure and potassium should be corrected when necessary and monitored during treatment, particularly in people with cardiovascular disease, heart failure or abnormal heart rhythms. Severe and sometimes fatal liver injury can occur, so liver-function tests are required before and during treatment. Adrenal insufficiency can occur, especially if the accompanying corticosteroid is interrupted or during infection or physiological stress. Strong CYP3A4 inducers can substantially reduce abiraterone exposure. Abiraterone also inhibits CYP2D6 and CYP2C8 and can alter exposure to susceptible medicines. Severe hypoglycaemia has been reported in patients with diabetes taking certain glucose-lowering medicines, including pioglitazone or repaglinide. Combining abiraterone plus prednisone/prednisolone with radium Ra-223 is not recommended because increased fractures and mortality have been observed. Patients should promptly report severe weakness, fainting, irregular heartbeat, marked swelling, shortness of breath, or symptoms suggesting liver injury.
Side effects and monitoring
Common effects reported with abiraterone treatment include fatigue, joint pain, high blood pressure, nausea, swelling from fluid retention, low potassium, hot flushes, diarrhoea, vomiting, cough and headache. Serious or less common problems include severe hypokalaemia, abnormal heart rhythms, heart failure, adrenal insufficiency, serious liver injury, severe hypoglycaemia in susceptible patients and hypersensitivity reactions. Seek urgent medical attention for trouble breathing, facial or throat swelling, fainting, severe or irregular heartbeat, or other signs of a serious allergic or cardiovascular reaction. Monitoring normally includes blood pressure, serum potassium, fluid retention and liver-function tests; glucose monitoring is particularly important in patients with diabetes.
Pregnancy
Abiraterone is not indicated for women and can cause fetal harm and pregnancy loss. Women who are pregnant or may become pregnant should not handle broken, crushed or damaged tablets without protective gloves. Men with female partners of reproductive potential should use effective contraception during treatment and for 3 weeks after the final dose.
Breastfeeding
Abiraterone is not approved for use in women. There are no adequate data on whether abiraterone is present in human milk or on its effects on a breastfed child or milk production.
Food and drink
Standard abiraterone acetate tablets should be taken on an empty stomach. Do not eat for at least 2 hours before and 1 hour after taking the medicine. Food can markedly increase abiraterone absorption and may increase the risk of adverse effects. Swallow the tablets whole with water.
Frequently asked questions
Why does abiraterone have to be taken on an empty stomach?
Food can substantially increase the amount of abiraterone absorbed into the bloodstream, which may increase adverse effects. Standard tablets should therefore be taken at least 2 hours after food and no food should be eaten for at least 1 hour afterward.
Why is prednisone or prednisolone used with abiraterone?
Abiraterone changes steroid-hormone production and can cause excess mineralocorticoid effects such as high blood pressure, low potassium and fluid retention. The prescribed corticosteroid helps reduce these effects and is an established part of abiraterone treatment.
Can abiraterone increase blood pressure or cause swelling?
Yes. High blood pressure and fluid retention are recognized effects of abiraterone, and low potassium can occur at the same time. Blood pressure, potassium and signs of fluid retention should be monitored during treatment.
Does abiraterone affect the liver?
Yes. Abiraterone can raise liver enzymes and, in some cases, cause severe liver injury. Liver-function blood tests are required before treatment and regularly during therapy.
What happens if I miss a dose of abiraterone?
For standard abiraterone tablets, if one daily dose is missed, take the usual prescribed dose the following day rather than taking an extra dose. If more than one dose is missed, contact the prescribing healthcare professional.
Can abiraterone interact with other medicines?
Yes. Strong CYP3A4-inducing medicines can reduce abiraterone levels, while abiraterone can increase exposure to some medicines metabolized by CYP2D6 or CYP2C8. The oncology team or pharmacist should review prescription medicines, over-the-counter products and herbal supplements before and during treatment.
Why are potassium and liver blood tests checked during treatment?
Abiraterone can lower potassium and cause liver toxicity. Regular laboratory monitoring helps identify these problems early so the treating team can manage treatment safely.
Can pregnant women handle Abirapro tablets?
Pregnant women or women who may become pregnant should not handle broken, crushed or damaged abiraterone tablets without protective gloves because the medicine can harm a developing fetus.
Can Cheap Generic Med ship Abirapro to the United States?
Cheap Generic Med serves the United States under its international shipping model, but medicine-specific prescription and personal-import requirements may apply. Delivery timing for this product is NOT VERIFIED without confirming the applicable order and destination details.
Will an Abirapro order have tracking?
Under the standard Cheap Generic Med fulfilment model, tracked international shipping is used and a tracking number should be provided after dispatch. Carrier systems may take 24–72 hours to begin showing movement.
Sources
Medical information notice: This information does not replace advice from a qualified healthcare professional. Use prescription medicine only as directed by the prescriber and the approved product information.
| Active Ingredients | Abiraterone Acetate (500Mg) |
|---|---|
| Manufacturer | Glenmark Pharmaceuticals Ltd |
| Packaging | Qty |
| strength | 500mg |
| Delivery Time | 6 To 15 days |
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