Permite Cream 5% (30 gm)

Dr. Emily Brown

Dr. Ryan Mitchell

## What is Permite Cream

Permite Cream is an external-use antiparasitic medicine used to treat Scabies, a contagious skin infestation caused by tiny mites that burrow into the skin. It contains FDA-approved Permethrin (5% w/w), a pyrethroid. Torrent Pharmaceuticals Ltd. manufactures Permite Cream 5% (30 g) in its GMP-compliant production plants.

Permite Cream 5% works by targeting the nervous system of Scabies mites. It disrupts sodium flow in mite nerve cells. This ultimately leads to paralysis and death. Uses of Permite Cream include clearing the infestation (the presence and multiplication of mites), reducing the spread of Scabies to others, and alleviating Scabies symptoms.

Permite is a prescription-only anti-scabies cream, so use it exactly as your doctor directs. Generally, it is usually applied as a thin layer over the affected skin, often over the whole body from the neck down, except the face and the eyes. Leave it on for the recommended duration, typically 8 to 14 hours, and then wash it off thoroughly.

If you miss an application, use it as soon as you remember, unless your doctor has given a different schedule. Do not overapply the cream, as excess use can increase skin irritation. Common side effects of Permethrin cream 30 g include mild rash, itching, burning, redness, and dryness. Consult a doctor if the effects persist longer or worsen.

Precautions include avoiding Permethrin if you are allergic to it or similar medicines. Do not apply it to open wounds or broken skin, or to the eyes or mouth. Do not immediately apply other topical treatments, lotions or ointments over this cream unless medically recommended.

Store anti-scabies cream with Permethrin below 30°C, away from direct heat, moisture, and children. Keep it out of reach of pets and children. Discard the tube as per its expiration date.

## What are the benefits of taking Permite Cream

Permethrin treats Scabies by directly targeting the mites on the skin. It also reduces the chances of passing the infection to others. Benefits of Permite Cream include:

Effectively kills mites: Permethrin 5% targets and destroys scabies mites and their eggs, clearing the infestation.

Relieves symptoms: As the mites are eliminated, itching and skin irritation gradually subsides.

Prevents spread to others: Effective treatment reduces the risk of transmitting scabies to close contacts and household members.

Easy, non-invasive treatment: It offers a convenient alternative to oral medicines, as it can be applied directly to the skin. Also, less than 2% of the medication is absorbed with minimal to no systemic effects.

## How quickly does Permite Cream work

Permite Cream typically starts working within 8-14 hours of application. It reaches its peak effectiveness when the cream remains on the skin for the full overnight period before washing. One application can clear mites, but a second application can be medically recommended after 7 days if needed.

Itching may continue for 2-4 weeks after treatment. Moreover, dose, condition severity, and coverage can affect the timing. Therefore, consult a doctor for personalized guidance on timing.

## Permite Cream: Generic Permethrin vs Elimite Cream

Permite Cream contains Permethrin 5%, the same FDA-approved active ingredient as the brand version, Elimite Cream, for Scabies treatment. Both topical medications work by paralyzing and killing Scabies mites and their eggs.

The key difference is cost. Brand Elimite costs around $97.42/tube at US pharmacies, while Permite Cream is available at Cheap Medicine Shop for $5.10/tube, making it a cost-effective alternative. Torrent Pharmaceuticals Ltd. manufactures the generic medication in GMP-compliant facilities.

The main differences between generic and brand products are the manufacturer, packaging, and inactive ingredients. These do not change the active ingredient, effectiveness, and mode of action.

## How to use Permite Cream

Use Permite exactly as prescribed by your doctor. Make sure not to apply it near your mouth, eyes, or to broken or wounded skin. General instructions for safe and proper application are:

Apply a thin layer of cream to clean, dry skin from the neck to the soles of your feet.

Cover all areas, including the buttocks, under the fingernails, and between fingers.

Leave the cream for 8 to 14 hours, usually overnight.

Wash it off thoroughly with clean water, and wear clean, washed clothes.

The second application is typically recommended 1 week after the first to kill mites that may have hatched from eggs after the first application.

## Strengths and Substitutes

Currently, only substitutes for Permite Cream are available at Cheap Medicine Shop. Use the following after consulting your doctor:

View all substitutes

## What are the side effects of Permite Cream

Like any other topical treatment, Permite Cream can trigger some mild adverse effects. These usually subside as the body develops tolerance. Seek medical consultation if one or more of the following side effects persist for a long time:

Itching

A burning sensation

Stinging

Redness

Dry skin

## Safety Advice

Liver Disease

Permite Cream is applied topically and is unlikely to have a major effect on the liver when used as directed. However, as a safety measure, consult a doctor if you have severe liver disease, especially if repeated applications are needed.

Kidney Impairment

Permethrin has limited to no systemic effects, so kidney-related concerns are uncommon. However, people with severe kidney impairment should talk to a doctor before using it, particularly if the skin is broken, inflamed, or widely affected.

Pregnant and Breastfeeding women

Use Permite only when advised in case of pregnancy and breastfeeding. Avoid applying it near the breast area while breastfeeding, and wash your hands properly after use to prevent accidental transfer to the newborn.

Avoid

Avoid Permite Cream if you are allergic to Permethrin, pyrethroids, pyrethrins, or any ingredient in the cream. Do not apply it near the eyes, mouth, open wounds, or broken skin. Also, do not use topical steroids like Hydrocortisone immediately before or during treatment unless advised by a doctor, as they can mask the Scabies symptoms.

## FAQs

## Is Permite effective for Scabies treatment?

Yes, Permite is effective for Scabies and is usually considered the first-line treatment. It kills the mites that cause infestations and eliminates symptoms such as itching and burning. When used as prescribed, typically on the whole body and left for the suggested time, it is highly effective.

## Does Permite Cream kill Scabies eggs?

Yes, Permite kills Scabies eggs by destroying the nervous system of the mites developing inside them. Even after mites and eggs are killed, itching can persist for a short time as the skin heals and reacts to dead mites.

## How quickly does Permite Cream relieve Scabies symptoms?

Permite Cream can relieve mild itching within 24 hours. However, intense rash and itching can take longer, typically 2 to 4 weeks, and in some individuals, even 6 weeks, to subside. Persistent itching for a while is normal as it’s your skin’s reaction to the dead mites.

## Can Permite Cream prevent Scabies from spreading?

Yes, if used properly and exactly as prescribed, Permite Cream can prevent Scabies from spreading. You will also need to clean your bedding, clothes, and towels, and treat anyone who was in contact with you. You will be considered non-infectious after 24 hours of starting the treatment.

## Can Permite Cream be used for head lice?

No, Permite Cream should not be used for head lice. It is a brand name for 5% Permethrin, specifically formulated for treating skin mites (Scabies). You can use Permethrin in the 1% formulation for head lice. Apply to the hair for 10 minutes and then rinse and dry.

## How long should Permite Cream stay on the skin?

Permite Cream is commonly left on the skin for 8 to 14 hours before washing it off, but follow your doctor’s exact instructions. Do not leave it on longer than advised, as this can increase skin irritation without making the treatment more effective.

## What is the active ingredient in Permite?

Permite Cream composition includes Permethrin 5% w/w as the active ingredient. Permethrin is an antiparasitic medicine used externally to kill Scabies mites and their eggs. Check the product label for inactive ingredients, especially if you have sensitive skin or allergies.