Selgin Tablet 5 Mg

Dr. Emily Brown

Dr. Ryan Mitchell

## What is Selgin 5 mg

Selgin tablet 5 mg is a prescription medication used in the management of Parkinson’s Disease. It is either used as initial monotherapy in early-stage disease or as an add-on treatment to Levodopa therapy when motor fluctuations become difficult to control. Intas Pharmaceuticals Ltd manufactures the tablets in GMP-compliant facilities.

It contains FDA-approved Selegiline 5 mg, a Monoamine Oxidase Type B (MAO-B) Inhibitor. Selegiline works by selectively and irreversibly inhibiting MAO-B, slowing the breakdown of dopamine and allowing higher dopamine levels to be maintained in the brain for longer.

When used alongside Levodopa, Selegiline also reduces the breakdown of dopamine produced from Levodopa. This extends its duration of action and smooths out the fluctuations in motor control that develop with long-term Levodopa use.

The standard dose is one 5 mg tablet taken twice daily, in the morning and at midday, or as directed by the doctor. Avoid taking it in the late afternoon or evening, as Selegiline can cause Insomnia when taken too late in the day.

Common Selgin side effects include nausea, dizziness, Insomnia, and dry mouth. Inform the doctor about all medications being taken, particularly antidepressants, as dangerous interactions can occur.

Store Selgin 5 mg tablets at room temperature below 25°C in a cool, dry place. Avoid exposure to direct sunlight and moisture. Keep out of reach of children and do not use after the expiry date.

## What are the benefits of taking Selgin 5 mg

Selegiline selectively blocks MAO-B, the enzyme that breaks down dopamine in the brain, preserving dopamine availability in the areas responsible for movement control. In early Parkinson’s Disease, this slows symptomatic progression by maintaining natural dopamine levels. In advanced disease, it extends and smooths the effect of Levodopa, reducing the off periods where motor symptoms return between doses.

## How to take Selgin 5 mg

Selgin 5 mg is a prescription medication that should be used only as directed by a healthcare professional. General usage guidelines are as follows:

Take 1 tablet in the morning and 1 at midday, or as directed by the doctor.

Swallow the tablet whole with a full glass of water.

Take it with or without food, though taking it with food may reduce nausea.

Do not exceed the prescribed dosage or take a dose in the late afternoon or evening, as this increases the chances of trouble sleeping.

## Strengths and Substitutes

Selgin is currently available in a 5 mg tablet strength. However, you can check these trusted alternatives for Parkinson’s Disease treatment available at Cheap Medicine Shop:

View all substitutes

## What are the side effects of Selgin 5 mg

Like any medication, Selgin 5 mg can cause side effects that are usually mild and temporary. However, consult a medical professional if they persist or worsen:

Nausea or stomach discomfort

Dizziness or lightheadedness

Insomnia or disturbed sleep

Dry mouth

Headache

## Safety Advice

Liver Disease

Selegiline is metabolized in the liver, and patients with significant liver disease can experience higher than normal levels of the medication in the bloodstream. Use Selgin with caution in patients with liver impairment and inform the doctor about any liver condition before starting treatment.

Kidney Impairment

People with mild to moderate kidney impairment can generally use Selgin 5 mg with caution. Severe kidney impairment can affect the elimination of Selegiline metabolites from the body. Inform the doctor of any kidney condition before starting treatment so that appropriate monitoring and any necessary dose adjustments can be implemented.

Pregnant and Breastfeeding women

Selgin 5 mg tablets are not recommended during pregnancy or breastfeeding unless necessary, as safety data in these groups is limited. Parkinson’s Disease primarily affects older adults, and the clinical need for this medication during pregnancy is rare. Consult a doctor to discuss safety or alternatives if treatment is necessary during pregnancy or while nursing.

Avoid

Do not use Selgin 5 mg alongside other MAO inhibitors, as combining them can cause a dangerous hypertensive crisis. Avoid using it with serotonergic antidepressants, including Selective Serotonin Reuptake Inhibitors (SSRIs) and tricyclic antidepressants, as the combination can cause Serotonin Syndrome, a potentially life-threatening reaction. Do not take with pethidine or other opioid analgesics, as serious adverse reactions have been reported. Avoid tyramine-rich foods such as aged cheese, cured meats, and fermented products at high Selegiline doses. Do not stop treatment without consulting the doctor, as abrupt discontinuation can worsen Parkinson’s symptoms. Avoid alcohol during treatment.

## FAQs

## Can Selgin tablet 5 mg be taken with Levodopa?

Yes, Selgin 5 mg is commonly prescribed alongside Levodopa to enhance and prolong its effects. Selegiline slows the breakdown of dopamine produced from Levodopa, reducing off periods and smoothing motor fluctuations. When both are used together, the doctor often reduces the Levodopa dose to prevent excessive dopamine activity.

## Can Selgin tablet 5 mg cause sleep problems?

Yes, Insomnia is a known side effect of Selegiline. It occurs because Selegiline is partially metabolized into amphetamine-related compounds that have a mild stimulant effect. Taking the second daily dose no later than midday significantly reduces the risk of sleep disturbance. Report persistent Insomnia to the doctor.

## Should alcohol be avoided with Selgin tablet 5 mg?

Yes, alcohol should be avoided during Selgin treatment. Alcohol can worsen dizziness and central nervous system side effects associated with Selegiline. It can also interfere with the medication’s effectiveness and increase the risk of falls in patients already affected by the balance difficulties of Parkinson’s Disease.

## Can Selgin tablet 5 mg be stopped suddenly?

No, Selgin should not be stopped suddenly without medical guidance. Abrupt discontinuation can cause a rapid worsening of Parkinson’s symptoms, including increased tremors, rigidity, and slowness of movement. The doctor will guide a gradual tapering schedule if discontinuation is necessary to allow the treatment plan to be adjusted safely.

## Does Selgin tablet 5 mg slow the progression of Parkinson’s Disease?

Selgin can help slow the progression of Parkinson’s Disease symptoms by increasing and preserving dopamine levels in the brain. In patients with early Parkinson’s Disease, it can delay symptom worsening and postpone the need for Levodopa treatment. However, it has not been conclusively proven to stop or reverse the disease.

## Can Selgin tablet 5 mg be used in elderly patients?

Yes, Selgin is mainly used in elderly patients with Parkinson’s Disease. However, elderly patients are more sensitive to side effects such as dizziness, confusion, and blood pressure changes. Starting on a lower dose with careful monitoring is standard practice, and any unusual symptoms should be reported to the doctor promptly.

## What foods should be avoided while taking Selgin 5 mg?

Tyramine-rich foods such as aged cheese, cured meats, and fermented soy products should be limited when taking Selgin. Consuming them can lead to elevated blood pressure, especially at higher doses of the medicine. Always confirm all specific dietary guidance with the treating doctor.