Sutent 12.5 Mg Capsule

Dr. Emily Brown

Dr. Ryan Mitchell

SKU

CMS3234

USA Brand Name

Sutent

Strength

12.5mg

Generic Name

Sunitinib

Manufacturer

Pfizer

## Sutent 12.5 Mg Capsule (Sunitinib)

## What Is The Generic Name For Sutent 12.5 Mg Capsule:

Sunitinib is the generic version for Sutent 12.5 mg Capsule

## Which USA Brand is Equivalent To Sutent 12.5 Mg Capsule (Sunitinib):

Sutent

## About Sutent 12.5 Mg Capsule (Sunitinib)

Sutent 12.5 mg Capsule contains an active ingredient, Sunitinib, which is used in the treatment of kidney cancer and gastrointestinal stromal tumour. Kidneys are fist-sized organs on both side of backbone above waist. The tubes inside filter and cleans the blood, taking out waste products and making urine. Kidney cancer forms in the lining of tiny tubes inside kidneys. Gastrointestinal stromal tumor (GISTs) is the tumors of the gut. The tumor cells in the wall of the gut begin to grow out of control. The tumors can be malignant (spread to other areas of the body) or benign (do not spread to other areas of the body). This medicine is available at all the leading pharmacy, drugstores, & medical supply stores & must be taken strictly by doctor’s prescription only.

## Manufacturer :

Pfizer Ltd. is one of the leading pharmaceutical companies which manufacture Sutent 12.5 mg Capsule.

## Strength :

Sutent 12.5 mg Capsule contains an active constituent, Sunitinib. It is obtainable in other substitutes also at all the leading online pharmacy, drugstores, and medical supply stores.

## What Are The Uses Of The Sutent 12.5 Mg Capsule (Sunitinib):

Sutent 12.5 mg Capsule is used in the treatment in following conditions:

Advanced Renal Cell Carcinoma (RCC)

Gastrointestinal stromal tumor

Pancreatic neuroendocrine tumours (pNET)

## How Sutent 12.5 Mg Capsule (Sunitinib) Works:

Sutent 12.5 mg Capsule has an active ingredient; Sunitinib. It is an anti-cancer medication that works by blocking the action of the abnormal protein which signals cancer cells to multiply. This helps in stopping or slowing the spread of cancer cells. Cellular signaling is stopped by Sunitinib by targeting multiple receptor tyrosine kinases (RTKs).These include all receptors for platelet-derived growth factor (PDGF-Rs) & vascular endothelial growth factor receptors (VEGFRs), that play a role in both tumor angiogenesis & tumor cell proliferation. The simultaneous inhibition of these targets therefore reduces tumor vascularization & triggers cancer cell apoptosis & thus results in tumor shrinkage.

## Before You Use Sutent 12.5 Mg Capsule (Sunitinib):

Make sure that:

You are not allergic to Sunitinib

You are not having any serious Disease

Your doctor must be learned about your medicinal history like your pre- existing disease, surgeries & Medications, Supplements, Food Habits, lifestyle, etc.

## What Should You Avoid While Taking Sutent 12.5 Mg Capsule (Sunitinib):

You should avoid taking alcohol

You should avoid driving

You should avoid taking Medicines without prescriptions

## When Not To Use Sutent 12.5 Mg Capsule (Sunitinib):

You should not take Sutent 12.5 mg Capsule if you:

Have ever noticed any Allergy/Hypersensitivity

Have liver problems

Have kidney problems

Have skin and tissue disorder

Have gastrointestinal disorder

Have hypertension

Have haematological disorder

Have cardiac disorder

Have thyroid

Have hypoglycemia

Are pregnant

Have infections

Are breastfeeding

## Tell Your Doctor If You:

Have Allergy to the Capsule

Are taking Alcohol or Other Drugs

Have Liver disease

Have infections

## Dosage :

Sutent 12.5 mg Capsule contains an active ingredient, Sunitinib, which is used in the treatment of kidney cancer and gastrointestinal stromal tumour. This medicine is available in different substitutes & strengths & has got to be purchased or given on doctor’s prescription only. You must consult your physician for adjustment of dosage & time of the medicine because age and severity of the disease differ from person to person and it can only be best judged by your doctor.

Adults are advised to take Sutent 12.5 mg Capsule at a fixed time with or without food as instructed by your Doctor. You must take Sutent 12.5 mg Capsule regularly on time for better results.

## How Much Of The Sutent 12.5 Mg Capsule (Sunitinib) to Be Used:

As Sutent 12.5 mg Capsule is available in various strengths and substitutes, Patients are always advised to follow their doctor’s prescriptions and instructions to take Sutent 12.5 mg Capsule. You must not take the Capsule on your own & for longer period than recommended by doctor.

## How To Take The Sutent 12.5 Mg Capsule (Sunitinib):

Take Sutent 12.5 mg Capsule in the dose and duration as advised by your doctor. Swallow the Capsule as a whole. You are suggested not to chew, crush or break the Capsule. Sutent 12.5 mg Capsule is to be taken with or without food, but it is better to take it at a fixed time.

## For How Long Should You Continue Using Sutent 12.5 Mg Capsule (Sunitinib):

You are always advised to take Sutent 12.5 mg Capsule as prescribed. Do not start/stop using this medicine yourself. You must strictly follow all the directions given by your doctor. You must not take the Capsule in larger or smaller quantity or for longer period than suggested by your doctor.

## Overdose :

You must seek medical emergency treatment and/ or contact your medical doctor instantly in case of any overdose symptoms. Emergency treatment will be initiated immediately by your medical doctor if they observe overdose symptoms.

## Missed Dose:

The missed dosage of the Capsule should be administered as soon as possible. You must strictly skip the missed dosage if it is already time for your next planned dosage. It is advised not to double the dosage of the treatment to make up for the missed dosage.

## What Are The Side Effects Of The Sutent 12.5 Mg Capsule (Sunitinib):

Bleeding gums

Blurred vision

Thyroid imbalances

Loss of appetite

Dizziness

Dry mouth

Headache

Nosebleed

Difficulty in breathing

Cough

Nausea and Vomiting

Constipation or diarrhea

Unusual tiredness and weakness

Weakness

Edema (swelling)

Rash

Abdominal pain

Dyspepsia

Discoloration of skin

Fever

Dry skin

Bleeding

High blood pressure

Painful blisters on hands and feet

Stomatitis (Inflammation of the mouth)

Hair discolouration

## What Are The Common Drug Interactions:

Few medicines have been reported to interact with Sutent 12.5 mg Capsule. These interactions may generate some needless or adverse effects and/or cause your drug not to work properly. You must always have a conversation with your doctor if you are taking other prescription/ Supplements so that well planned medication can be given. It interacts with the following medicines:

Efavirenz

Mifepristone

Clozapine

Amiodarone

Ceritinib

It can also interact with following disease condition:

Infections

Lung Toxicity

Adrenal Toxicity

Liver Disease

Cardiovascular disorders

Dermtologic Toxicity

Bleeding

Hypertension

Hypoglycemia

Osteonecrosis of the jaw (ONJ)

Thyroid disorders

Kidney Disease

You must avoid consumption of grapefruit or grapefruit juice during treatment with this medicine as it may increase the risk of side effects which affect bone marrow function, resulting in lowering the blood cell count.

## Warning And Precaution:

Sutent 12.5 mg Capsule can worsen the conditions like:

Allergy

Kidney/ Liver disease

Sutent 12.5 mg Capsule is not recommended for use in children under 18 years of age

You must use a reliable contraceptive method to prevent pregnancy while you are on this medication

You must regularly get your blood tests done to monitor your blood cells, liver and kidney function, and lipid levels during treatment with this medicine

You must drink plenty of fluids and inform your doctor if diarrhea doesn’t stop or if you find blood in your stools

You must monitor your blood pressure regularly while taking this medication

You must not take this medicine if you are pregnant, planning to conceive or breastfeeding

You must not drive or operate heavy machinery at the same time as taking this medicine as it may cause dizziness

Always consult with your medical doctor straight away to get best possible treatment if you are observing any of the above mentioned conditions.

## Things To Remember:

Keep the Sutent 12.5 mg Capsule out of reach and sight of the children

This medicine is strictly used with caution for treatment of children

Sutent 12.5 mg Capsule is not recommended for use in pregnant women due to the increased risk of harmful effects on the unborn baby

You must always check up the information in particular written on the leaflet/ insert of the medicine

Always consult your medical doctor if you have any uncertainty in case of the dosage, time & strength of the medicine.

## Indications:

Sutent 12.5 mg Capsule should be taken for cancer treatment. Do not take this prescription for longer period than suggested by the medical doctor.

## Storage :

Store the Sutent 12.5 mg Capsule at room temperature in dark and dry place. Make sure the Capsule is intact & not damaged while purchasing or storing.